Paré, Guillaume

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

MAGIC, Speliotes, E. K., on behalf of Procardis Consortium, Willer, C. J., Berndt, S. I., Monda, K. L., Thorleifsson, G., Jackson, A. U., Allen, H. L., Lindgren, C. M., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,912

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Lango Allen, H., Estrada, K., Lettre, G., Berndt, S. I., Weedon, M. N., Rivadeneira, F., Willer, C. J., Jackson, A. U., Vedantam, S., Raychaudhuri, S., et al. (2010) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 1,945

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Program, T. M. V., Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 1,381

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

MAGIC, Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 931

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 704

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., et al. (2024) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 606

Enabling the genomic revolution in Africa

The H3Africa Consortium, Matovu, E., Bucheton, B., Chisi, J., Enyaru, J., Hertz-Fowler, C., Koffi, M., Macleod, A., Mumba, D., Sidibe, I., et al. (2014) · Science

Genetics, Bioinformatics, and Biomedical ResearchBiotechnology and Related Fields

Cited by 519

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

The GIANT Consortium, Elks, C. E., Perry, J. R. B., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Byrne, E. M., et al. (2010) · Nature Genetics

Hypothalamic control of reproductive hormonesGenetic Associations and Epidemiology

Cited by 504

Genome-wide association studies identify loci associated with age at menarche and age at natural menopause

He, C., Kraft, P., Chen, C., Buring, J. E., Paré, G., Hankinson, S. E., Chanock, S. J., Ridker, P. M., Hunter, D. J., & Chasman, D. I. (2009) · Nature Genetics

Genetic Associations and EpidemiologyHypothalamic control of reproductive hormones

Cited by 379

Association Between Shortened Leukocyte Telomere Length and Cardiometabolic Outcomes: Systematic Review and Meta-Analysis

D’Mello, M. J. J., Ross, S. A., Briel, M., Anand, S. S., Gerstein, H., & Paré, G. (2015) · Circulation: Cardiovascular Genetics

Telomeres, Telomerase, and SenescenceGenetic Associations and Epidemiology

Cited by 350

Novel Association of ABO Histo-Blood Group Antigen with Soluble ICAM-1: Results of a Genome-Wide Association Study of 6,578 Women

Paré, G., Chasman, D. I., Kellogg, M., Zee, R. Y. L., Rifai, N., Badola, S., Miletich, J. P., & Ridker, P. M. (2008) · PLoS Genetics

Genetic Associations and EpidemiologyBlood groups and transfusion

Cited by 341

Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis

Chasman, D. I., Paré, G., Mora, S., Hopewell, J. C., Peloso, G., Clarke, R., Cupples, L. A., Hamsten, A., Kathiresan, S., Mälarstig, A., et al. (2009) · PLoS Genetics

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 337

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss

Day, E. A., Ford, R. J., Smith, B. K., Mohammadi-Shemirani, P., Morrow, M. R., Gutgesell, R. M., Lu, R., Raphenya, A. R., Kabiri, M., McArthur, A. G., et al. (2019) · Nature Metabolism

GDF15 and Related BiomarkersRegulation of Appetite and Obesity

Cited by 307

Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia

Morrow, M. R., Batchuluun, B., Wu, J., Ahmadi, E., Leroux, J. M., Mohammadi-Shemirani, P., Desjardins, E. M., Wang, Z., Tsakiridis, E. E., Lavoie, D. C. T., et al. (2022) · Cell Metabolism

Liver Disease Diagnosis and TreatmentCancer, Lipids, and Metabolism

Cited by 199

Polygenic risk score predicts prevalence of cardiovascular disease in patients with familial hypercholesterolemia

Paquette, M., Chong, M., Thériault, S., Dufour, R., Paré, G., & Baass, A. (2017) · Journal of Clinical Lipidology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 115

Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease

Sjaarda, J., Gerstein, H., Chong, M., Yusuf, S., Meyre, D., Anand, S. S., Hess, S., & Paré, G. (2018) · Journal of the American College of Cardiology

Genetic Associations and EpidemiologyAtherosclerosis and Cardiovascular Diseases

Cited by 94

Effect of Bile Acid Sequestrants on the Risk of Cardiovascular Events: A Mendelian Randomization Analysis

Ross, S., D’Mello, M., Anand, S. S., Eikelboom, J., CARDIoGRAMplusC4D Consortium*, Stewart, A. F. R., Samani, N. J., Roberts, R., & Paré, G. (2015) · Circulation: Cardiovascular Genetics

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 90

A machine-learning heuristic to improve gene score prediction of polygenic traits

Paré, G., Mao, S., & Deng, W. Q. (2017) · Scientific Reports

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 85

Validation of the classification for type 2 diabetes into five subgroups: a report from the ORIGIN trial

Pigeyre, M., Hess, S., Gomez, M. F., Asplund, O., Groop, L., Paré, G., & Gerstein, H. (2022) · Diabetologia

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 79

Identifying Novel Biomarkers for Cardiovascular Events or Death in People With Dysglycemia

Gerstein, H. C., Paré, G., McQueen, M. J., Haenel, H., Lee, S. F., Pogue, J., Maggioni, A. P., Yusuf, S., & Hess, S. (2015) · Circulation

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and Research

Cited by 69

Global Assessment of Mendelian Stroke Genetic Prevalence in 101 635 Individuals From 7 Ethnic Groups

Grami, N., Chong, M., Lali, R., Mohammadi-Shemirani, P., Henshall, D. E., Rannikmäe, K., & Paré, G. (2020) · Stroke

Cerebrovascular and genetic disordersGenomics and Rare Diseases

Cited by 38

Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice

Desjardins, E. M., Wu, J., Lavoie, D. C. T., Ahmadi, E., Townsend, L. K., Morrow, M. R., Wang, D., Tsakiridis, E. E., Batchuluun, B., Fayyazi, R., et al. (2023) · Cell Reports Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 33