Colonna, Marco

Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination

Hou, J., Zhou, Y., Cai, Z., Terekhova, M., Swain, A., Andhey, P. S., Guimaraes, R. M., Ulezko Antonova, A., Qiu, T., Sviben, S., et al. (2023) · Cell Reports

Multiple Sclerosis Research StudiesSingle-cell and spatial transcriptomics

Cited by 85

TREM2 promotes lung fibrosis via controlling alveolar macrophage survival and pro-fibrotic activity

Cui, H., Banerjee, S., Xie, N., Hussain, M., Jaiswal, A., Liu, H., Kulkarni, T., Antony, V. B., Liu, R.-M., Colonna, M., et al. (2025) · Nature Communications

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisInflammation biomarkers and pathways

Cited by 74

An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination

Barclay, K. M., Abduljawad, N., Cheng, Z., Kim, M. W., Zhou, L., Yang, J., Rustenhoven, J., Mazzitelli, J. A., Smyth, L. C. D., Kapadia, D., et al. (2024) · Immunity

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 65

Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal

Kang, S. S., Kurti, A., Baker, K. E., Liu, C.-C., Colonna, M., Ulrich, J. D., Holtzman, D. M., Bu, G., & Fryer, J. D. (2018) · Human Molecular Genetics

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 62

TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti–PD-1 tumor immunotherapy

Di Luccia, B., Molgora, M., Khantakova, D., Jaeger, N., Chang, H.-W., Czepielewski, R. S., Helmink, B. A., Onufer, E. J., Fachi, J. L., Bhattarai, B., et al. (2024) · Science Immunology

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 59

Human inhibitory and activating Ig-like receptors which modulate the function of myeloid cells

Dietrich, J., Nakajima, H., & Colonna, M. (2000) · Microbes and Infection

Phagocytosis and Immune RegulationImmune Cell Function and Interaction

Cited by 53

TAK1 targeting by glucocorticoids determines JNK and IκB regulation in Toll-like receptor–stimulated macrophages

Bhattacharyya, S., Ratajczak, C. K., Vogt, S. K., Kelley, C., Colonna, M., Schreiber, R. D., & Muglia, L. J. (2010) · Blood

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 53

DAP12 signaling: from immune cells to bone modeling and brain myelination

Colonna, M. (2003) · Journal of Clinical Investigation

Bone Metabolism and DiseasesNeurogenesis and neuroplasticity mechanisms

Cited by 50

Interferon responses in viral pneumonias

Grajales-Reyes, G. E., & Colonna, M. (2020) · Science

interferon and immune responsesSARS-CoV-2 and COVID-19 Research

Cited by 46

Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains

Zhu, C., Herrmann, U. S., Li, B., Abakumova, I., Moos, R., Schwarz, P., Rushing, E. J., Colonna, M., & Aguzzi, A. (2015) · Neurobiology of Aging

Prion Diseases and Protein MisfoldingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 44

Regulation of microglial survival and proliferation in health and diseases

Ulland, T. K., Wang, Y., & Colonna, M. (2015) · Seminars in Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 43

Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications

Czajkowsky, D. M., Andersen, J. T., Fuchs, A., Wilson, T. J., Mekhaiel, D., Colonna, M., He, J., Shao, Z., Mitchell, D. A., Wu, G., et al. (2015) · Scientific Reports

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stability

Cited by 38

Amplification of autoimmune organ damage by NKp46-activated ILC1s

Biniaris-Georgallis, S.-I., Aschman, T., Stergioula, K., Schreiber, F., Jafari, V., Taranko, A., Karmalkar, T., Kasapi, A., Lenac Rovis, T., Jelencic, V., et al. (2024) · Nature

Systemic Lupus Erythematosus ResearchIL-33, ST2, and ILC Pathways

Cited by 34

Two Distinct Myeloid Subsets at the Term Human Fetal-Maternal Interface

Costa, M. L., Robinette, M. L., Bugatti, M., Longtine, M. S., Colvin, B. N., Lantelme, E., Vermi, W., Colonna, M., Nelson, D. M., & Cella, M. (2017) · Frontiers in Immunology

Reproductive System and PregnancyPregnancy and preeclampsia studies

Cited by 22

Acute TREM2 inhibition depletes MAFB-high microglia and hinders remyelination

Hou, J., Magliozzi, R., Chen, Y., Wu, J., Wulf, J., Strout, G., Fang, X., & Colonna, M. (2025) · Proceedings of the National Academy of Sciences

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 20

Somatic mutations reveal the ontogeny of human microglia

Belk, J. A., Zhang, Y., Shi, Q., Ma, L., Kalluru, R., Enciso, A. M., Reilly, E. E., Weiss, J., Li, R., Eastman, A. E., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 3

Cell signaling pathways discovery from multi-modal data

He, C., Simpson, C., Cossentino, I., Zhang, B., Tkachev, S., Eddins, D. J., Kosters, A., Yang, J., Sheth, S., Levy, T., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory)

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 3