Kepp, Oliver

Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

Menger, L., Vacchelli, E., Adjemian, S., Martins, I., Ma, Y., Shen, S., Yamazaki, T., Sukkurwala, A. Q., Michaud, M., Mignot, G., et al. (2012) · Science Translational Medicine

Immunotherapy and Immune ResponsesCell death mechanisms and regulation

Cited by 423

Mitophagy: An Emerging Role in Aging and Age-Associated Diseases

Chen, G., Kroemer, G., & Kepp, O. (2020) · Frontiers in Cell and Developmental Biology

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 359

Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response

Churin, Y., Al-Ghoul, L., Kepp, O., Meyer, T. F., Birchmeier, W., & Naumann, M. (2003) · The Journal of Cell Biology

Helicobacter pylori-related gastroenterology studiesGastric Cancer Management and Outcomes

Cited by 354

The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death

Panaretakis, T., Joza, N., Modjtahedi, N., Tesniere, A., Vitale, I., Durchschlag, M., Fimia, G. M., Kepp, O., Piacentini, M., Froehlich, K.-U., et al. (2008) · Cell Death & Differentiation

Endoplasmic Reticulum Stress and DiseaseCell death mechanisms and regulation

Cited by 344

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

Bonora, M., Wieckowski, M. R., Chinopoulos, C., Kepp, O., Kroemer, G., Galluzzi, L., & Pinton, P. (2015) · Oncogene

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 330

Crizotinib-induced immunogenic cell death in non-small cell lung cancer

Liu, P., Zhao, L., Pol, J., Levesque, S., Petrazzuolo, A., Pfirschke, C., Engblom, C., Rickelt, S., Yamazaki, T., Iribarren, K., et al. (2019) · Nature Communications

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 302

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1

Vicencio, J. M., Ortiz, C., Criollo, A., Jones, A. W. E., Kepp, O., Galluzzi, L., Joza, N., Vitale, I., Morselli, E., Tailler, M., et al. (2009) · Cell Death & Differentiation

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 289

Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity

Shen, S., Niso-Santano, M., Adjemian, S., Takehara, T., Malik, S. A., Minoux, H., Souquere, S., Mariño, G., Lachkar, S., Senovilla, L., et al. (2012) · Molecular Cell

Autophagy in Disease and TherapyCytokine Signaling Pathways and Interactions

Cited by 285

Molecular mechanisms of regulated necrosis

Galluzzi, L., Kepp, O., Krautwald, S., Kroemer, G., & Linkermann, A. (2014) · Seminars in Cell & Developmental Biology

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 258

A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers

Fidelle, M., Rauber, C., Alves Costa Silva, C., Tian, A.-L., Lahmar, I., de La Varende, A.-L. M., Zhao, L., Thelemaque, C., Lebhar, I., Messaoudene, M., et al. (2023) · Science

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 243

Autophagy mediates pharmacological lifespan extension by spermidineand resveratrol

Morselli, E., Galluzzi, L., Kepp, O., Criollo, A., Maiuri, M. C., Tavernarakis, N., Madeo, F., & Kroemer, G. (2009) · Aging

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 213

Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

Uhl, M., Kepp, O., Jusforgues-Saklani, H., Vicencio, J.-M., Kroemer, G., & Albert, M. L. (2009) · Cell Death & Differentiation

Immunotherapy and Immune ResponsesAutophagy in Disease and Therapy

Cited by 196

Regulated cell death and adaptive stress responses

Galluzzi, L., Bravo-San Pedro, J. M., Kepp, O., & Kroemer, G. (2016) · Cellular and Molecular Life Sciences

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 177

Cisplatin Resistance Associated with PARP Hyperactivation

Michels, J., Vitale, I., Galluzzi, L., Adam, J., Olaussen, K. A., Kepp, O., Senovilla, L., Talhaoui, I., Guegan, J., Enot, D. P., et al. (2013) · Cancer Research

PARP inhibition in cancer therapyCell death mechanisms and regulation

Cited by 176

Mitochondrial control of the NLRP3 inflammasome

Kepp, O., Galluzzi, L., & Kroemer, G. (2011) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 168

Prognostic and predictive value of DAMPs and DAMP-associated processes in cancer

Fucikova, J., Moserova, I., Urbanova, L., Bezu, L., Kepp, O., Cremer, I., Salek, C., Strnad, P., Kroemer, G., Galluzzi, L., et al. (2015) · Frontiers in Immunology

Immunotherapy and Immune ResponsesImmune Response and Inflammation

Cited by 159

Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos

Vitale, I., Senovilla, L., Jemaà, M., Michaud, M., Galluzzi, L., Kepp, O., Nanty, L., Criollo, A., Rello‐Varona, S., Manic, G., et al. (2010) · The EMBO Journal

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

Cited by 146

Autophagy-dependent ATP release from dying cells via lysosomal exocytosis

Wang, Y., Martins, I., Ma, Y., Kepp, O., Galluzzi, L., & Kroemer, G. (2013) · Autophagy

Autophagy in Disease and TherapyAdenosine and Purinergic Signaling

Cited by 137

Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

Fucikova, J., Truxova, I., Hensler, M., Becht, E., Kasikova, L., Moserova, I., Vosahlikova, S., Klouckova, J., Church, S. E., Cremer, I., et al. (2016) · Blood

Acute Myeloid Leukemia ResearchImmunotherapy and Immune Responses

Cited by 135

A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis

Büttner, S., Ruli, D., Vögtle, F., Galluzzi, L., Moitzi, B., Eisenberg, T., Kepp, O., Habernig, L., Carmona‐Gutierrez, D., Rockenfeller, P., et al. (2011) · The EMBO Journal

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 133

Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis

Yonekura, S., Terrisse, S., Alves Costa Silva, C., Lafarge, A., Iebba, V., Ferrere, G., Goubet, A.-G., Fahrner, J.-E., Lahmar, I., Ueda, K., et al. (2022) · Cancer Discovery

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 112

Non‐apoptotic functions of apoptosis‐regulatory proteins

Galluzzi, L., Kepp, O., Trojel‐Hansen, C., & Kroemer, G. (2012) · The EMBO Reports

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 109

Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity

Abdellatif, M., Trummer-Herbst, V., Heberle, A. M., Humnig, A., Pendl, T., Durand, S., Cerrato, G., Hofer, S. J., Islam, M., Voglhuber, J., et al. (2022) · Circulation

Genetics, Aging, and Longevity in Model OrganismsGrowth Hormone and Insulin-like Growth Factors

Cited by 108

Trial Watch: experimental TLR7/TLR8 agonists for oncological indications

Frega, G., Wu, Q., Le Naour, J., Vacchelli, E., Galluzzi, L., Kroemer, G., & Kepp, O. (2020) · OncoImmunology

Immunotherapy and Immune ResponsesImmune Response and Inflammation

Cited by 108