Cummings, Jeffrey

Practical recommendations for timely, accurate diagnosis of symptomatic Alzheimer’s disease (MCI and dementia) in primary care: a review and synthesis

Liss, J. L., Seleri Assunção, S., Cummings, J., Atri, A., Geldmacher, D. S., Candela, S. F., Devanand, D. P., Fillit, H. M., Susman, J., Mintzer, J., et al. (2021) · Journal of Internal Medicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 312

Lessons Learned from Alzheimer Disease: Clinical Trials with Negative Outcomes

Cummings, J. (2018) · Clinical and Translational Science

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 298

Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer’s disease mutations

Ringman, J. M., O'Neill, J., Geschwind, D., Medina, L., Apostolova, L. G., Rodriguez, Y., Schaffer, B., Varpetian, A., Tseng, B., Ortiz, F., et al. (2007) · Brain

Dementia and Cognitive Impairment ResearchAdvanced Neuroimaging Techniques and Applications

Cited by 290

Biomarkers in Alzheimer’s disease: role in early and differential diagnosis and recognition of atypical variants

Dubois, B., von Arnim, C. A. F., Burnie, N., Bozeat, S., & Cummings, J. (2023) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 288

Blood-based biomarkers for Alzheimer’s disease: Current state and future use in a transformed global healthcare landscape

Hampel, H., Hu, Y., Cummings, J., Mattke, S., Iwatsubo, T., Nakamura, A., Vellas, B., O’Bryant, S., Shaw, L. M., Cho, M., et al. (2023) · Neuron

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 283

Donanemab: Appropriate use recommendations

Rabinovici, G. D., Selkoe, D. J., Schindler, S. E., Aisen, P., Apostolova, L. G., Atri, A., Greenberg, S. M., Hendrix, S. B., Petersen, R. C., Weiner, M., et al. (2025) · The Journal of Prevention of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 278

Association between healthy lifestyle and memory decline in older adults: 10 year, population based, prospective cohort study

Jia, J., Zhao, T., Liu, Z., Liang, Y., Li, F., Li, Y., Liu, W., Li, F., Shi, S., Zhou, C., et al. (2023) · BMJ

Dementia and Cognitive Impairment ResearchCardiovascular Health and Risk Factors

Cited by 252

New approaches to symptomatic treatments for Alzheimer’s disease

Cummings, J. (2021) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 226

Aducanumab produced a clinically meaningful benefit in association with amyloid lowering

Cummings, J., Aisen, P., Lemere, C., Atri, A., Sabbagh, M., & Salloway, S. (2021) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 224

A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia

Xiao, S., Chan, P., Wang, T., Hong, Z., Wang, S., Kuang, W., He, J., Pan, X., Zhou, Y., Ji, Y., et al. (2021) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 224

Improvement in behavioural symptoms in patients with moderate to severe Alzheimer's disease by memantine: a pooled data analysis

Gauthier, S., Loft, H., & Cummings, J. (2008) · International Journal of Geriatric Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 220

Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial

Cummings, J. L., Lyketsos, C. G., Peskind, E. R., Porsteinsson, A. P., Mintzer, J. E., Scharre, D. W., De La Gandara, J. E., Agronin, M., Davis, C. S., Nguyen, U., et al. (2015) · JAMA

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 209

Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer’s disease

Fang, J., Zhang, P., Zhou, Y., Chiang, C.-W., Tan, J., Hou, Y., Stauffer, S., Li, L., Pieper, A. A., Cummings, J., et al. (2021) · Nature Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 206

Drug repositioning and repurposing for Alzheimer disease

Ballard, C., Aarsland, D., Cummings, J., O’Brien, J., Mills, R., Molinuevo, J. L., Fladby, T., Williams, G., Doherty, P., Corbett, A., et al. (2020) · Nature Reviews Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 201

Biochemical markers in persons with preclinical familial Alzheimer disease

Ringman, J. M., Younkin, S. G., Pratico, D., Seltzer, W., Cole, G. M., Geschwind, D. H., Rodriguez-Agudelo, Y., Schaffer, B., Fein, J., Sokolow, S., et al. (2008) · Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 198

Designing the next-generation clinical care pathway for Alzheimer’s disease

Hampel, H., Au, R., Mattke, S., van der Flier, W. M., Aisen, P., Apostolova, L., Chen, C., Cho, M., De Santi, S., Gao, P., et al. (2022) · Nature Aging

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 191

Double-blind, placebo-controlled, proof-of-concept trial of bexarotene in moderate Alzheimer’s disease

Cummings, J. L., Zhong, K., Kinney, J. W., Heaney, C., Moll-Tudla, J., Joshi, A., Pontecorvo, M., Devous, M., Tang, A., & Bena, J. (2016) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 190

Alzheimer's disease drug development pipeline: 2025

Cummings, J. L., Zhou, Y., Lee, G., Zhong, K., Fonseca, J., Leisgang‐Osse, A. M., & Cheng, F. (2025) · Alzheimer's & Dementia: Translational Research & Clinical Interventions

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 190

Structural correlates of apathy in Alzheimer's disease

Apostolova, L. G., Akopyan, G. G., Partiali, N., Steiner, C. A., Dutton, R. A., Hayashi, K. M., Dinov, I. D., Toga, A. W., Cummings, J. L., & Thompson, P. M. (2007) · Dementia and Geriatric Cognitive Disorders

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 190

Increased basal ganglia iron levels in Huntington disease

Bartzokis, G., Cummings, J., Perlman, S., Hance, D. B., & Mintz, J. (1999) · Archives of Neurology

Genetic Neurodegenerative DiseasesNeurological diseases and metabolism

Cited by 183

Frequency and Characteristics of Anxiety Among Patients With Alzheimer's Disease and Related Dementias

Porter, V. R., Buxton, W. G., Fairbanks, L. A., Strickland, T., O'Connor, S. M., Rosenberg-Thompson, S., & Cummings, J. L. (2003) · The Journal of Neuropsychiatry and Clinical Neurosciences

Dementia and Cognitive Impairment ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 182

Clinical Trials for Disease-Modifying Therapies in Alzheimer’s Disease: A Primer, Lessons Learned, and a Blueprint for the Future

Cummings, J., Ritter, A., & Zhong, K. (2018) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 176

NEUROBEHAVIORAL AND NEUROPSYCHIATRIC SYMPTOMS IN ALZHEIMER'S DISEASE

Chung, J. A., & Cummings, J. L. (2000) · Neurologic Clinics

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 174

Efficacy and safety of brexpiprazole for the treatment of agitation in Alzheimer's dementia: two 12-week, randomized, double-blind, placebo-controlled trials

Grossberg, G. T., Kohegyi, E., Mergel, V., Josiassen, M. K., Meulien, D., Hobart, M., Slomkowski, M., Baker, R. A., McQuade, R. D., & Cummings, J. L. (2020) · The American Journal of Geriatric Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 169