Cummings, Jeffrey

evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer’s disease

Cummings, J. L., Atri, A., Feldman, H. H., Hansson, O., Sano, M., Knop, F. K., Johannsen, P., León, T., & Scheltens, P. (2025) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 168

ADCOMS: a composite clinical outcome for prodromal Alzheimer's disease trials

Wang, J., Logovinsky, V., Hendrix, S. B., Stanworth, S. H., Perdomo, C., Xu, L., Dhadda, S., Do, I., Rabe, M., Luthman, J., et al. (2016) · Journal of Neurology, Neurosurgery & Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 160

Comparison of neuropsychological functioning in Alzheimer’s disease and frontotemporal dementia

Pachana, N. A., Boone, K. B., Miller, B. L., Cummings, J. L., & Berman, N. (1996) · Journal of the International Neuropsychological Society

Dementia and Cognitive Impairment ResearchHistorical and Modern Theater Studies

Cited by 154

Left frontotemporal hypoperfusion is associated with aggression in patients with dementia

Hirono, N., Mega, M. S., Dinov, I. D., Mishkin, F., & Cummings, J. L. (2000) · Archives of Neurology

Dementia and Cognitive Impairment ResearchNeural and Behavioral Psychology Studies

Cited by 153

Trial of pimavanserin in dementia-related psychosis

Tariot, P. N., Cummings, J. L., Soto-Martin, M. E., Ballard, C., Erten-Lyons, D., Sultzer, D. L., Devanand, D. P., Weintraub, D., McEvoy, B., Youakim, J. M., et al. (2021) · New England Journal of Medicine

Schizophrenia research and treatmentDementia and Cognitive Impairment Research

Cited by 145

Early-onset Alzheimer’s disease is associated with greater pathologic burden.

Marshall, G. A., Fairbanks, L. A., Tekin, S., Vinters, H. V., & Cummings, J. L. (2007) · Journal of Geriatric Psychiatry and Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 143

Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease

Fang, J., Zhang, P., Wang, Q., Chiang, C.-W., Zhou, Y., Hou, Y., Xu, J., Chen, R., Zhang, B., Lewis, S. J., et al. (2022) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsComputational Drug Discovery Methods

Cited by 140

The National Institute on Aging—Alzheimer's Association Framework on Alzheimer's disease: Application to clinical trials

Cummings, J. (2019) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 140

DEFINING DISEASE MODIFYING THERAPY FOR ALZHEIMER’S DISEASE

Cummings, J., & Fox, N. (2017) · The Journal of Prevention of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 139

Brexpiprazole for the Treatment of Agitation in Alzheimer Dementia: A Randomized Clinical Trial

Lee, D., Slomkowski, M., Hefting, N., Chen, D., Larsen, K. G., Kohegyi, E., Hobart, M., Cummings, J. L., & Grossberg, G. T. (2023) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 135

Angular Gyrus Syndrome Simulating Alzheimer's Disease

Benson, D. F., Cummings, J. L., & Tsai, S. Y. (1982) · Archives of Neurology

Dementia and Cognitive Impairment ResearchNeurobiology of Language and Bilingualism

Cited by 129

The Alzheimer’s disease drug development landscape

van Bokhoven, P., de Wilde, A., Vermunt, L., Leferink, P. S., Heetveld, S., Cummings, J., Scheltens, P., & Vijverberg, E. G. B. (2021) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 123

Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer’s disease

Xu, J., Mao, C., Hou, Y., Luo, Y., Binder, J. L., Zhou, Y., Bekris, L. M., Shin, J., Hu, M., Wang, F., et al. (2022) · Cell Reports

Alzheimer's disease research and treatmentsBioinformatics and Genomic Networks

Cited by 115

Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials

Cummings, J. L., Atri, A., Sano, M., Zetterberg, H., Scheltens, P., Knop, F. K., Johannsen, P., Wichmann, C. A., Abschneider, R. M., Leon, T., et al. (2026) · The Lancet

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 110

Gantenerumab: An anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer’s disease

Bateman, R. J., Cummings, J., Schobel, S., Salloway, S., Vellas, B., Boada, M., Black, S. E., Blennow, K., Fontoura, P., Klein, G., et al. (2022) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 109

Alzheimer's drug‐development pipeline: 2016

Cummings, J., Morstorf, T., & Lee, G. (2016) · Alzheimer's & Dementia: Translational Research & Clinical Interventions

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 108

Association of GSK3B with Alzheimer disease and frontotemporal dementia

Schaffer, B. A. J., Bertram, L., Miller, B. L., Mullin, K., Weintraub, S., Johnson, N., Bigio, E. H., Mesulam, M., Wiedau-Pazos, M., Jackson, G. R., et al. (2008) · Archives of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 100

The Role of Neuropsychiatric Symptoms in Research Diagnostic Criteria for Neurodegenerative Diseases

Cummings, J. (2021) · The American Journal of Geriatric Psychiatry

Dementia and Cognitive Impairment ResearchParkinson's Disease Mechanisms and Treatments

Cited by 96

Agitation in cognitive disorders: progress in the International Psychogeriatric Association consensus clinical and research definition.

Sano, M., Cummings, J., Auer, S., Bergh, S., Fischer, C. E., Gerritsen, D., Grossberg, G., Ismail, Z., Lanctôt, K., Lapid, M. I., et al. (2024) · International Psychogeriatrics

Dementia and Cognitive Impairment ResearchIntensive Care Unit Cognitive Disorders

Cited by 91

Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease

Wessels, A. M., Lines, C., Stern, R. A., Kost, J., Voss, T., Mozley, L. H., Furtek, C., Mukai, Y., Aisen, P. S., Cummings, J. L., et al. (2020) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 86

A COMBINED MEASURE OF COGNITION AND FUNCTION FOR CLINICAL TRIALS: THE INTEGRATED ALZHEIMER’S DISEASE RATING SCALE (IADRS)

Wessels, A. M., Siemers, E. R., Yu, P., Andersen, S. W., Holdridge, K. C., Sims, J. R., Sundell, K., Stern, Y., Rentz, D. M., Dubois, B., et al. (2015) · The Journal of Prevention of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 86

Age and Rate of Cognitive Decline in Alzheimer Disease: Implications for Clinical Trials

Bernick, C., Cummings, J., Raman, R., Sun, X., & Aisen, P. (2012) · Archives of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 85

Further analyses of the safety of verubecestat in the phase 3 EPOCH trial of mild-to-moderate Alzheimer’s disease

Egan, M. F., Mukai, Y., Voss, T., Kost, J., Stone, J., Furtek, C., Mahoney, E., Cummings, J. L., Tariot, P. N., Aisen, P. S., et al. (2019) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 81

Repurposed agents in the Alzheimer’s disease drug development pipeline

Bauzon, J., Lee, G., & Cummings, J. (2020) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 77