Cited by 109Personality Traits and PsychologyLipoproteins and Cardiovascular HealthCardiac Health and Mental Health

Cholesterol, triglycerides, and the Five-Factor Model of personality

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Sutin, Angelina R., Terracciano, Antonio, Deiana, Barbara, Uda, Manuela, Schlessinger, David, Lakatta, Edward G., Costa Jr., Paul T.·2010·Biological Psychology

Abstract

Unhealthy lipid levels are among the leading controllable risk factors for coronary heart disease. To identify the psychological factors associated with dyslipidemia, this study investigates the personality correlates of cholesterol (total, LDL, and HDL) and triglycerides. A community-based sample (N=5532) from Sardinia, Italy, had their cholesterol and triglyceride levels assessed and completed a comprehensive personality questionnaire, the NEO-PI-R. All analyses controlled for age, sex, BMI, smoking, drinking, hypertension, and diabetes. Low Conscientiousness and traits related to impulsivity were associated with lower HDL cholesterol and higher triglycerides. Compared to the lowest 10%, those who scored in top 10% on Impulsivity had a 2.5 times greater risk of exceeding the clinical threshold for elevated triglycerides (OR=2.51, CI=1.56-4.07). In addition, sex moderated the association between trait depression (a component of Neuroticism) and HDL cholesterol, such that trait depression was associated with lower levels of HDL cholesterol in women but not men. When considering the connection between personality and health, unhealthy lipid profiles may be one intermediate biomarker between personality and morbidity and mortality.

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Crossref · 10.1016/j.biopsycho.2010.01.012

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  • The increasing inclusion of biomarkers in personality-longevity studies is beginning to illuminate biological pathways such as systemic inflammation and artery calcification.

    “Second, the increasing inclusion of biomarkers in personality-longevity studies is beginning to illuminate biological pathways such as systemic inflammation [65, 66, 218, 219] and artery calcification [220, 221]”

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Authors
Sutin, A. R., Terracciano, A., Deiana, B., Uda, M., Schlessinger, D., Lakatta, E. G., & Costa Jr., P. T.
Affiliations
  • National Institutes of Health (US)
  • Institute of Genetic and Biomedical Research (IT)
Corresponding author
Sutin, Angelina R.
Venue
Biological Psychology
Publisher
Elsevier BV
Published
2010-05
Volume
84
Issue
2
Pages
186-191
ISSN
0301-0511 (ISSN-L)
OpenAlex
W2070292687
Cited by
109
References
61
Citations by year
2026: 1 · 2025: 4 · 2024: 7 · 2023: 5 · 2022: 6 · 2021: 4 · 2020: 7 · 2019: 7 · 2018: 8 · 2017: 7 · 2016: 4 · 2015: 7 · 2014: 9 · 2013: 8 · 2012: 10
FWCI
11.63
Type
journal article
Language
en
Open access
Locations
  • Biological Psychology (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (Z99 AG999999)
  • National Institute on Aging (ZIAAG000180, ZIAAG000197, ZIAAG000183)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
  • Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords
dyslipidemia, cholesterol, triglycerides, Big Five personality traits, personality traits, impulsivity, conscientiousness, trait depression, neuroticism, HDL cholesterol, LDL cholesterol, coronary heart disease risk, sex differences, Sardinia
MeSH terms
Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Blood Chemical Analysis, Cholesterol, Female, Humans, Italy, Male, Middle Aged, Personality, Personality Inventory, Residence Characteristics, Sex Factors, Triglycerides, Logistic Models, Young Adult

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