Layé, Sophie

Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice

Layé, S., Parnet, P., Goujon, E., & Dantzer, R. (1994) · Molecular Brain Research

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 500

Microbiota-derived metabolites as drivers of gut–brain communication

Ahmed, H., Leyrolle, Q., Koistinen, V., Kärkkäinen, O., Layé, S., Delzenne, N., & Hanhineva, K. (2022) · Gut Microbes

Gut microbiota and healthTryptophan and brain disorders

Cited by 462

Anti-inflammatory effects of omega-3 fatty acids in the brain: physiological mechanisms and relevance to pharmacology

Layé, S., Nadjar, A., Joffre, C., & Bazinet, R. P. (2018) · Pharmacological Reviews

Fatty Acid Research and HealthNeuroinflammation and Neurodegeneration Mechanisms

Cited by 420

Chronic low-grade inflammation in elderly persons is associated with altered tryptophan and tyrosine metabolism: role in neuropsychiatric symptoms

Capuron, L., Schroecksnadel, S., Féart, C., Aubert, A., Higueret, D., Barberger-Gateau, P., Layé, S., & Fuchs, D. (2011) · Biological Psychiatry

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 368

Molecular Basis of Sickness Behaviora

DANTZER, R., BLUTHÉ, R., GHEUSI, G., CREMONA, S., LAYÉ, S., PARNET, P., & KELLEY, K. W. (1998) · Annals of the New York Academy of Sciences

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 249

Diet-induced obesity progressively alters cognition, anxiety-like behavior and lipopolysaccharide-induced depressive-like behavior: focus on brain indoleamine 2,3-dioxygenase activation

André, C., Dinel, A.-L., Ferreira, G., Layé, S., & Castanon, N. (2014) · Brain Behavior and Immunity

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 241

Polyunsaturated fatty acids, neuroinflammation and well being

Layé, S. (2010) · Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)

Fatty Acid Research and HealthTryptophan and brain disorders

Cited by 167

Metformin promotes anxiolytic and antidepressant-like responses in insulin-resistant mice by decreasing circulating branched-chain amino acids

Zemdegs, J., Martin, H., Pintana, H., Bullich, S., Manta, S., Marqués, M. A., Moro, C., Layé, S., Ducrocq, F., Chattipakorn, N., et al. (2019) · The Journal of Neuroscience

Treatment of Major DepressionTryptophan and brain disorders

Cited by 151

Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota

Madore, C., Leyrolle, Q., Lacabanne, C., Benmamar-Badel, A., Joffre, C., Nadjar, A., & Layé, S. (2016) · Neural Plasticity

Autism Spectrum Disorder ResearchFatty Acid Research and Health

Cited by 141

Adrenalectomy enhances pro-inflammatory cytokines gene expression, in the spleen, pituitary and brain of mice in response to lipopolysaccharide

Goujon, E., Parnet, P., Layé, S., Combe, C., & Dantzer, R. (1996) · Molecular Brain Research

Stress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms

Cited by 128

Endocannabinoid-Mediated plasticity in nucleus accumbens controls vulnerability to anxiety after social defeat stress

Bosch-Bouju, C., Larrieu, T., Linders, L., Manzoni, O. J., & Layé, S. (2016) · Cell Reports

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 100

Adipose Inflammation in Obesity: Relationship With Circulating Levels of Inflammatory Markers and Association With Surgery-Induced Weight Loss

Lasselin, J., Magne, E., Beau, C., Ledaguenel, P., Dexpert, S., Aubert, A., Layé, S., & Capuron, L. (2014) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesBariatric Surgery and Outcomes

Cited by 96

Fatigue symptoms relate to systemic inflammation in patients with type 2 diabetes

Lasselin, J., Layé, S., Dexpert, S., Aubert, A., Gonzalez, C., Gin, H., & Capuron, L. (2012) · Brain, Behavior, and Immunity

Adipokines, Inflammation, and Metabolic DiseasesTryptophan and brain disorders

Cited by 77

Maternal high-fat diet prevents developmental programming by early-life stress

Rincel, M., Lépinay, A. L., Delage, P., Fioramonti, J., Théodorou, V. S., Layé, S., & Darnaudéry, M. (2016) · Translational Psychiatry

Birth, Development, and HealthMaternal Mental Health During Pregnancy and Postpartum

Cited by 69

Dietary supplementation of omega-3 fatty acids rescues fragile X phenotypes in Fmr1-Ko mice

Pietropaolo, S., Goubran, M., Joffre, C., Aubert, A., Lemaire-Mayo, V., Crusio, W. E., & Layé, S. (2014) · Psychoneuroendocrinology

Genetics and Neurodevelopmental DisordersFatty Acid Research and Health

Cited by 63

Low-grade inflammation is a major contributor of impaired attentional set shifting in obese subjects

Lasselin, J., Magne, E., Beau, C., Aubert, A., Dexpert, S., Carrez, J., Layé, S., Forestier, D., Ledaguenel, P., & Capuron, L. (2016) · Brain Behavior and Immunity

Adipokines, Inflammation, and Metabolic DiseasesNeural and Behavioral Psychology Studies

Cited by 53

Insulin modulates emotional behavior through a serotonin-dependent mechanism

Martin, H., Bullich, S., Martinat, M., Chataigner, M., Di Miceli, M., Simon, V., Clark, S., Butler, J., Schell, M., Chopra, S., et al. (2024) · Molecular Psychiatry

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 50

Direct and indirect effects of lipids on microglia function

Leyrolle, Q., Layé, S., & Nadjar, A. (2019) · Neuroscience Letters

Neuroinflammation and Neurodegeneration MechanismsFatty Acid Research and Health

Cited by 50