Lees, Andrew J.

Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease

Robak, L. A., Jansen, I. E., van Rooij, J., Uitterlinden, A. G., Kraaij, R., Jankovic, J., Heutink, P., Shulman, J. M., International Parkinson’s Disease Genomics Consortium (IPDGC), Nalls, M. A., et al. (2017) · Brain

Lysosomal Storage Disorders ResearchParkinson's Disease Mechanisms and Treatments

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Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype

Houlden, H., Baker, M., Morris, H. R., MacDonald, N., Pickering–Brown, S., Adamson, J., Lees, A. J., Rossor, M. N., Quinn, N. P., Kertesz, A., et al. (2001) · Neurology

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 409

Does corticobasal degeneration exist? A clinicopathological re-evaluation

Ling, H., O'Sullivan, S. S., Holton, J. L., Revesz, T., Massey, L. A., Williams, D. R., Paviour, D. C., & Lees, A. J. (2010) · Brain

Dementia and Cognitive Impairment ResearchParkinson's Disease Mechanisms and Treatments

Cited by 394

Conjugates of Catecholamines with Cysteine and GSH in Parkinson's Disease: Possible Mechanisms of Formation Involving Reactive Oxygen Species

Spencer, J. P. E., Jenner, P., Daniel, S. E., Lees, A. J., Marsden, D. C., & Halliwell, B. (1998) · Journal of Neurochemistry

Parkinson's Disease Mechanisms and TreatmentsRedox biology and oxidative stress

Cited by 373

Prognosis and neuropathologic correlation of clinical subtypes of Parkinson disease

De Pablo-Fernández, E., Lees, A. J., Holton, J. L., & Warner, T. T. (2019) · JAMA Neurology

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 332

A phase 2 trial of the GSK‐3 inhibitor tideglusib in progressive supranuclear palsy

Tolosa, E., Litvan, I., Höglinger, G. U., Burn, D., Lees, A., Andrés, M. V., Gómez‐Carrillo, B., León, T., del Ser, T., & for the TAUROS Investigators (2014) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 320

Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial

Boxer, A. L., Lang, A. E., Grossman, M., Knopman, D. S., Miller, B. L., Schneider, L. S., Doody, R. S., Lees, A., Golbe, L. I., Williams, D. R., et al. (2014) · The Lancet Neurology

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 294

Nonmotor symptoms as presenting complaints in Parkinson’s disease: a clinicopathological study

O'Sullivan, S. S., Williams, D. R., Gallagher, D. A., Massey, L. A., Silveira‐Moriyama, L., & Lees, A. J. (2008) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 290

Argyrophilic Grain Disease Is a Sporadic 4-Repeat Tauopathy

Togo, T., Sahara, N., Yen, S.-H., Cookson, N., Ishizawa, T., Hutton, M., de Silva, R., Lees, A., & Dickson, D. W. (2002) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 273

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

Guerreiro, R., Ross, O. A., Kun-Rodrigues, C., Hernandez, D. G., Orme, T., Eicher, J. D., Shepherd, C. E., Parkkinen, L., Darwent, L., Heckman, M. G., et al. (2018) · The Lancet Neurology

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 270

Dopamine Dysregulation Syndrome: An Overview of its Epidemiology, Mechanisms and Management

OʼSullivan, S. S., Evans, A. H., & Lees, A. J. (2009) · CNS Drugs

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 265

Decreased ferritin levels in brain in Parkinson's disease

Dexter, D. T., Carayon, A., Vidailhet, M., Ruberg, M., Agid, F., Agid, Y., Lees, A. J., Wells, F. R., Jenner, P., & Marsden, C. D. (1990) · Journal of Neurochemistry

Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolism

Cited by 258

Dopamine dysregulation syndrome in Parkinson's disease

Evans, A. H., & Lees, A. J. (2004) · Current Opinion in Neurology

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 257

Mixed pathologies including chronic traumatic encephalopathy account for dementia in retired association football (soccer) players

Ling, H., Morris, H. R., Neal, J. W., Lees, A. J., Hardy, J., Holton, J. L., Revesz, T., & Williams, D. D. R. (2017) · Acta Neuropathologica

Traumatic Brain Injury ResearchDementia and Cognitive Impairment Research

Cited by 252

Increased Alzheimer pathology in Parkinson's disease related to antimuscarinic drugs

Perry, E. K., Kilford, L., Lees, A. J., Burn, D. J., & Perry, R. H. (2003) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 231

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies

Bras, J., Guerreiro, R., Darwent, L., Parkkinen, L., Ansorge, O., Escott-Price, V., Hernandez, D. G., Nalls, M. A., Clark, L. N., Honig, L. S., et al. (2014) · Human Molecular Genetics

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 230

Constipation preceding Parkinson's disease: a systematic review and meta-analysis

Adams-Carr, K. L., Bestwick, J. P., Shribman, S., Lees, A., Schrag, A., & Noyce, A. J. (2016) · Journal of Neurology, Neurosurgery & Psychiatry

Parkinson's Disease Mechanisms and TreatmentsGastrointestinal motility and disorders

Cited by 228

BRADYPHRENIA IN PARKINSON'S DISEASE AND PSYCHOMOTOR RETARDATION IN DEPRESSIVE ILLNESS: AN EXPERIMENTAL STUDY

ROGERS, D., LEES, A. J., SMITH, E., TRIMBLE, M., & STERN, G. M. (1987) · Brain

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 218

Donepezil in Parkinson's disease dementia: A randomized, double‐blind efficacy and safety study

Dubois, B., Tolosa, E., Katzenschlager, R., Emre, M., Lees, A. J., Schumann, G., Pourcher, E., Gray, J., Thomas, G., Swartz, J., et al. (2012) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 202

Neural response to visual sexual cues in dopamine treatment-linked hypersexuality in Parkinson's disease

Politis, M., Loane, C., Wu, K., O’Sullivan, S. S., Woodhead, Z., Kiferle, L., Lawrence, A. D., Lees, A. J., & Piccini, P. (2013) · Brain

Sexuality, Behavior, and TechnologyParkinson's Disease Mechanisms and Treatments

Cited by 191

Dystonia in parkinson's disease: Clinical and pharmacological features

Poewe, W. H., Lees, A. J., & Stern, G. M. (1988) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 162

Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration

Tsika, E., Glauser, L., Moser, R., Fiser, A., Daniel, G., Sheerin, U.-M., Lees, A., Troncoso, J. C., Lewis, P. A., Bandopadhyay, R., et al. (2014) · Human Molecular Genetics

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 159

Anal Sphincter Dysfunction in Parkinson's Disease

Mathers, S. E., Kempster, P. A., Law, P. J., Frankel, J. P., Bartram, C. I., Lees, A. J., Stern, G. M., & Swash, M. (1989) · Archives of Neurology

Parkinson's Disease Mechanisms and TreatmentsGastrointestinal motility and disorders

Cited by 158

THE NEUROLOGY OF OBSESSIONAL SLOWNESS

HYMAS, N., LEES, A., BOLTON, D., EPPS, K., & HEAD, D. (1991) · Brain

Obsessive-Compulsive Spectrum DisordersDeep Brain Stimulation and Movement Disorders

Cited by 152