Brown, Patrick O.

Cluster analysis and display of genome-wide expression patterns

Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences

Gene expression and cancer classificationBioinformatics and Genomic Networks

Cited by 16,184

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

Alizadeh, A. A., Eisen, M. B., Davis, R. E., Ma, C., Lossos, I. S., Rosenwald, A., Boldrick, J. C., Sabet, H., Tran, T., Yu, X., et al. (2000) · Nature

Lymphoma Diagnosis and TreatmentBreast Cancer Treatment Studies

Cited by 9,925

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

Schena, M., Shalon, D., Davis, R. W., & Brown, P. O. (1995) · Science

Gene expression and cancer classificationAdvanced Biosensing Techniques and Applications

Cited by 9,609

Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes

Gasch, A. P., Spellman, P. T., Kao, C. M., Carmel-Harel, O., Eisen, M. B., Storz, G., Botstein, D., & Brown, P. O. (2000) · Molecular Biology of the Cell

Fungal and yeast genetics researchBacterial Genetics and Biotechnology

Cited by 4,815

Development of the Human Infant Intestinal Microbiota

Palmer, C., Bik, E. M., DiGiulio, D. B., Relman, D. A., & Brown, P. O. (2007) · PLoS Biology

Gut microbiota and healthInfant Nutrition and Health

Cited by 2,877

Systematic variation in gene expression patterns in human cancer cell lines

Ross, D. T., Scherf, U., Eisen, M. B., Perou, C. M., Rees, C., Spellman, P., Iyer, V., Jeffrey, S. S., Van de Rijn, M., Waltham, M., et al. (2000) · Nature Genetics

Gene expression and cancer classificationBreast Cancer Treatment Studies

Cited by 2,088

Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors

Whitfield, M. L., Sherlock, G., Saldanha, A. J., Murray, J. I., Ball, C. A., Alexander, K. E., Matese, J. C., Perou, C. M., Hurt, M. M., Brown, P. O., et al. (2002) · Molecular Biology of the Cell

Gene expression and cancer classificationCancer-related Molecular Pathways

Cited by 1,527

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

Chang, H. Y., Nuyten, D. S. A., Sneddon, J. B., Hastie, T., Tibshirani, R., Sørlie, T., Dai, H., He, Y. D., van't Veer, L. J., Bartelink, H., et al. (2005) · Proceedings of the National Academy of Sciences

Breast Cancer Treatment StudiesGene expression and cancer classification

Cited by 981

Integration of murine leukemia virus DNA depends on mitosis.

Roe, T., Reynolds, T. C., Yu, G., & Brown, P. O. (1993) · The EMBO Journal

T-cell and Retrovirus StudiesHIV Research and Treatment

Cited by 921

Comparative Gene Expression Profiles Following UV Exposure in Wild-Type and SOS-Deficient Escherichia coli

Courcelle, J., Khodursky, A., Peter, B., Brown, P. O., & Hanawalt, P. C. (2001) · Genetics

Bacterial Genetics and BiotechnologyDNA Repair Mechanisms

Cited by 853

Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae

Arava, Y., Wang, Y., Storey, J. D., Liu, C. L., Brown, P. O., & Herschlag, D. (2003) · Proceedings of the National Academy of Sciences

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 663

Diverse RNA-Binding Proteins Interact with Functionally Related Sets of RNAs, Suggesting an Extensive Regulatory System

Hogan, D. J., Riordan, D. P., Gerber, A. P., Herschlag, D., & Brown, P. O. (2008) · PLoS Biology

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 609

Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae

Dunham, M. J., Badrane, H., Ferea, T., Adams, J., Brown, P. O., Rosenzweig, F., & Botstein, D. (2002) · Proceedings of the National Academy of Sciences

Evolution and Genetic DynamicsFungal and yeast genetics research

Cited by 564

'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns

Hastie, T., Tibshirani, R., Eisen, M. B., Alizadeh, A., Levy, R., Staudt, L., Chan, W. C., Botstein, D., & Brown, P. (2000) · Genome Biology

Gene expression and cancer classificationBioinformatics and Genomic Networks

Cited by 547

Genomic Expression Responses to DNA-damaging Agents and the Regulatory Role of the Yeast ATR Homolog Mec1p

Gasch, A. P., Huang, M., Metzner, S., Botstein, D., Elledge, S. J., & Brown, P. O. (2001) · Molecular Biology of the Cell

DNA Repair MechanismsFungal and yeast genetics research

Cited by 542

Gene expression patterns in human placenta

Sood, R., Zehnder, J. L., Druzin, M. L., & Brown, P. O. (2006) · Proceedings of the National Academy of Sciences

Pregnancy and preeclampsia studiesReproductive System and Pregnancy

Cited by 454

Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA

Hendrickson, D. G., Hogan, D. J., McCullough, H. L., Myers, J. W., Herschlag, D., Ferrell, J. E., & Brown, P. O. (2009) · PLoS Biology

MicroRNA in disease regulationRNA and protein synthesis mechanisms

Cited by 418

Genome-wide Analysis of Gene Expression Regulated by the Calcineurin/Crz1p Signaling Pathway in Saccharomyces cerevisiae

Yoshimoto, H., Saltsman, K., Gasch, A. P., Li, H. X., Ogawa, N., Botstein, D., Brown, P. O., & Cyert, M. S. (2002) · Journal of Biological Chemistry

Fungal and yeast genetics researchSignaling Pathways in Disease

Cited by 404

Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein

Brown, P. O., Bowerman, B., Varmus, H. E., & Bishop, J. M. (1989) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 399

Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray

Johannes, G., Carter, M. S., Eisen, M. B., Brown, P. O., & Sarnow, P. (1999) · Proceedings of the National Academy of Sciences

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 394

Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae

Sudarsanam, P., Iyer, V. R., Brown, P. O., & Winston, F. (2000) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 389

Cell-type specific gene expression profiles of leukocytes in human peripheral blood

Palmer, C., Diehn, M., Alizadeh, A. A., & Brown, P. O. (2006) · BMC Genomics

Gene expression and cancer classificationBioinformatics and Genomic Networks

Cited by 331

Generalized singular value decomposition for comparative analysis of genome-scale expression data sets of two different organisms

Alter, O., Brown, P. O., & Botstein, D. (2003) · Proceedings of the National Academy of Sciences

Gene expression and cancer classificationBioinformatics and Genomic Networks

Cited by 304

Diverse and Specific Gene Expression Responses to Stresses in Cultured Human Cells

Murray, J. I., Whitfield, M. L., Trinklein, N. D., Myers, R. M., Brown, P. O., & Botstein, D. (2004) · Molecular Biology of the Cell

Heat shock proteins researchFungal and yeast genetics research

Cited by 300