Ruvkun, Gary

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Wightman, B., Ha, I., & Ruvkun, G. (1993) · Cell

Developmental Biology and Gene RegulationRNA Research and Splicing

Cited by 4,292

Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing

Grishok, A., Pasquinelli, A. E., Conte, D., Li, N., Parrish, S., Ha, I., Baillie, D. L., Fire, A., Ruvkun, G., & Mello, C. C. (2001) · Cell

RNA Interference and Gene DeliveryPlant Molecular Biology Research

Cited by 1,908

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

Lee, S. S., Lee, R. Y. N., Fraser, A. G., Kamath, R. S., Ahringer, J., & Ruvkun, G. (2003) · Nature Genetics

Genetics, Aging, and Longevity in Model OrganismsMitochondrial Function and Pathology

Cited by 969

The lin-41 RBCC Gene Acts in the C. elegans Heterochronic Pathway between the let-7 Regulatory RNA and the LIN-29 Transcription Factor

Slack, F. J., Basson, M., Liu, Z., Ambros, V., Horvitz, H. R., & Ruvkun, G. (2000) · Molecular Cell

Developmental Biology and Gene RegulationMicroRNA in disease regulation

Cited by 751

DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism

Lee, S. S., Kennedy, S., Tolonen, A. C., & Ruvkun, G. (2003) · Science

Genetics, Aging, and Longevity in Model OrganismsFOXO transcription factor regulation

Cited by 669

C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

O'Rourke, E. J., Soukas, A. A., Carr, C. E., & Ruvkun, G. (2009) · Cell Metabolism

Lipid metabolism and biosynthesisGenetics, Aging, and Longevity in Model Organisms

Cited by 452

The Genetics of Aging

Finch, C. E., & Ruvkun, G. (2001) · Annual Review of Genomics and Human Genetics

Genetics, Aging, and Longevity in Model OrganismsNeurobiology and Insect Physiology Research

Cited by 446

Control of Developmental Timing by MicroRNAs and Their Targets

Pasquinelli, A. E., & Ruvkun, G. (2002) · Annual Review of Cell and Developmental Biology

Developmental Biology and Gene RegulationMicroRNA in disease regulation

Cited by 341

The Taxonomy of Developmental Control in Caenorhabditis elegans

Ruvkun, G., & Hobert, O. (1998) · Science

Developmental Biology and Gene RegulationGenomics and Phylogenetic Studies

Cited by 305

Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death

Kirienko, N. V., Kirienko, D. R., Larkins-Ford, J., Wählby, C., Ruvkun, G., & Ausubel, F. M. (2013) · Cell Host & Microbe

Bacterial biofilms and quorum sensingBacterial Genetics and Biotechnology

Cited by 221

DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity

Riedel, C. G., Dowen, R. H., Lourenco, G. F., Kirienko, N. V., Heimbucher, T., West, J. A., Bowman, S. K., Kingston, R. E., Dillin, A., Asara, J. M., et al. (2013) · Nature Cell Biology

FOXO transcription factor regulationGenetics, Aging, and Longevity in Model Organisms

Cited by 207

A novel repeat domain that is often associated with RING finger and B-box motifs

Slack, F. J., & Ruvkun, G. (1998) · Trends in Biochemical Sciences

Ubiquitin and proteasome pathwaysGenomics and Chromatin Dynamics

Cited by 151

Dominant gain-of-function mutations that lead to misregulation of the C. elegans heterochronic gene lin-14, and the evolutionary implications of dominant mutations in pattern-formation genes

Ruvkun, G., Wightman, B., Bürglin, T., & Arasu, P. (1991) · Development

Developmental Biology and Gene RegulationRNA Research and Splicing

Cited by 25