Weissman, Drew

PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake

Parhiz, H., Shuvaev, V. V., Pardi, N., Khoshnejad, M., Kiseleva, R. Y., Brenner, J. S., Uhler, T., Tuyishime, S., Mui, B. L., Tam, Y. K., et al. (2018) · Journal of Controlled Release

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 233

mRNA transcript therapy

Weissman, D. (2015) · Expert Review of Vaccines

RNA Interference and Gene DeliveryImmunotherapy and Immune Responses

Cited by 228

Ionizable lipid nanoparticles for in utero mRNA delivery

Riley, R. S., Kashyap, M. V., Billingsley, M. M., White, B., Alameh, M.-G., Bose, S. K., Zoltick, P. W., Li, H., Zhang, R., Cheng, A. Y., et al. (2021) · Science Advances

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 222

HPLC purification of in vitro transcribed long RNA

Weissman, D., Pardi, N., Muramatsu, H., & Karikó, K. (2013) · Methods in molecular biology

RNA and protein synthesis mechanismsRNA Interference and Gene Delivery

Cited by 180

Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy

Swingle, K. L., Safford, H. C., Geisler, H. C., Hamilton, A. G., Thatte, A. S., Billingsley, M. M., Joseph, R. A., Mrksich, K., Padilla, M. S., Ghalsasi, A. A., et al. (2023) · Journal of the American Chemical Society

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 145

Nucleoside modified mRNA vaccines for infectious diseases

Pardi, N., & Weissman, D. (2017) · Methods in molecular biology

RNA Interference and Gene DeliveryImmunotherapy and Immune Responses

Cited by 129

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia

Swingle, K. L., Hamilton, A. G., Safford, H. C., Geisler, H. C., Thatte, A. S., Palanki, R., Murray, A. M., Han, E. L., Mukalel, A. J., Han, X., et al. (2025) · Nature

RNA Interference and Gene DeliveryPregnancy and preeclampsia studies

Cited by 129

Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models

Hajnik, R. L., Plante, J. A., Liang, Y., Alameh, M.-G., Tang, J., Bonam, S. R., Zhong, C., Adam, A., Scharton, D., Rafael, G. H., et al. (2022) · Science Translational Medicine

SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing

Cited by 122

Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques

Pardi, N., LaBranche, C. C., Ferrari, G., Cain, D. W., Tombácz, I., Parks, R. J., Muramatsu, H., Mui, B. L., Tam, Y. K., Karikó, K., et al. (2019) · Molecular Therapy - Nucleic Acids

HIV Research and TreatmentSARS-CoV-2 and COVID-19 Research

Cited by 103

Messenger RNA-Based Vaccines Against Infectious Diseases

Alameh, M.-G., Weissman, D., & Pardi, N. (2020) · Current Topics in Microbiology and Immunology

Immunotherapy and Immune ResponsesRNA Interference and Gene Delivery

Cited by 96

Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria

Raj, D. K., Das Mohapatra, A., Jnawali, A., Zuromski, J., Jha, A., Cham-Kpu, G., Sherman, B., Rudlaff, R. M., Nixon, C. E., Hilton, N., et al. (2020) · Nature

Malaria Research and ControlBlood groups and transfusion

Cited by 93

Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus

Furey, C., Scher, G., Ye, N., Kercher, L., DeBeauchamp, J., Crumpton, J. C., Jeevan, T., Patton, C., Franks, J., Rubrum, A., et al. (2024) · Nature Communications

Influenza Virus Research StudiesVirology and Viral Diseases

Cited by 79

mRNA vaccine with unmodified uridine induces robust type I interferon-dependent anti-tumor immunity in a melanoma model

Sittplangkoon, C., Alameh, M.-G., Weissman, D., Lin, P. J. C., Tam, Y. K., Prompetchara, E., & Palaga, T. (2022) · Frontiers in Immunology

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 79

Ionizable Lipid Nanoparticles for Therapeutic Base Editing of Congenital Brain Disease

Palanki, R., Bose, S. K., Dave, A., White, B. M., Berkowitz, C., Luks, V., Yaqoob, F., Han, E., Swingle, K. L., Menon, P., et al. (2023) · ACS Nano

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 77

Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery

Swingle, K. L., Billingsley, M. M., Bose, S. K., White, B., Palanki, R., Dave, A., Patel, S. K., Gong, N., Hamilton, A. G., Alameh, M.-G., et al. (2022) · Journal of Controlled Release

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 64

Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice

Willis, E., Pardi, N., Parkhouse, K., Mui, B. L., Tam, Y. K., Weissman, D., & Hensley, S. E. (2020) · Science Translational Medicine

Influenza Virus Research StudiesImmunotherapy and Immune Responses

Cited by 54

Hindlimb suspension and spe-like radiation impairs clearance of bacterial infections

Li, M., Holmes, V., Zhou, Y., Ni, H., Sanzari, J. K., Kennedy, A. R., & Weissman, D. (2014) · PLoS ONE

Spaceflight effects on biologyEffects of Radiation Exposure

Cited by 43

Protection against herpes simplex virus type 2 infection in a neonatal murine model using a trivalent nucleoside-modified mRNA in lipid nanoparticle vaccine

LaTourette, P. C., Awasthi, S., Desmond, A., Pardi, N., Cohen, G. H., Weissman, D., & Friedman, H. M. (2020) · Vaccine

Herpesvirus Infections and TreatmentsVirology and Viral Diseases

Cited by 39

Acute biological effects of simulating the whole-body radiation dose distribution from a solar particle event using a porcine model

Wilson, J. M., Sanzari, J. K., Diffenderfer, E. S., Yee, S. S., Seykora, J. T., Maks, C., Ware, J. H., Litt, H. I., Reetz, J. A., McDonough, J., et al. (2011) · Radiation Research

Effects of Radiation ExposureRadiation Therapy and Dosimetry

Cited by 24

Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy in mice

Smith, A. R., Rizvi, F., Everton, E., Adeagbo, A., Wu, S., Tam, Y., Muramatsu, H., Pardi, N., Weissman, D., & Gouon-Evans, V. (2024) · Nature Communications

Liver physiology and pathologyRNA Interference and Gene Delivery

Cited by 18

Safety and immunogenicity of a prefusion non-stabilized spike protein mRNA COVID-19 vaccine: a phase I trial

Gatechompol, S., Kittanamongkolchai, W., Ketloy, C., Prompetchara, E., Thitithanyanont, A., Jongkaewwattana, A., Buranapraditkun, S., Alameh, M.-G., Ubolyam, S., Sophonphan, J., et al. (2022) · Nature Microbiology

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 15

Immunogenicity and Protective Efficacy of a SARS-CoV-2 mRNA Vaccine Encoding Secreted Non-Stabilized Spike Protein in Mice

Prompetchara, E., Ketloy, C., Alameh, M.-G., Tarakhet, K., Kaewpang, P., Yostrerat, N., Pitakpolrat, P., Buranapraditkun, S., Manopwisedcharoen, S., Thitithanyanont, A., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 1