Lesch, Klaus-Peter

When the Serotonin Transporter Gene Meets Adversity: The Contribution of Animal Models to Understanding Epigenetic Mechanisms in Affective Disorders and Resilience

Lesch, K.-P. (2011) · Current Topics in Behavioral Neurosciences

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 86

ADHD related behaviors are associated with brain activation in the reward system

Stark, R., Bauer, E., Merz, C. J., Zimmermann, M., Reuter, M., Plichta, M. M., Kirsch, P., Lesch, K. P., Fallgatter, A. J., Vaitl, D., et al. (2011) · Neuropsychologia

Attention Deficit Hyperactivity DisorderNeural and Behavioral Psychology Studies

Cited by 82

Association between reward‐related activation in the ventral striatum and trait reward sensitivity is moderated by dopamine transporter genotype

Hahn, T., Heinzel, S., Dresler, T., Plichta, M. M., Renner, T. J., Markulin, F., Jakob, P. M., Lesch, K., & Fallgatter, A. J. (2011) · Human Brain Mapping

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 78

Functional Amygdala-Hippocampus Connectivity During Anticipation of Aversive Events is Associated with Gray's Trait “Sensitivity to Punishment”

Hahn, T., Dresler, T., Plichta, M. M., Ehlis, A.-C., Ernst, L. H., Markulin, F., Polak, T., Blaimer, M., Deckert, J., Lesch, K.-P., et al. (2010) · Biological Psychiatry

Neural and Behavioral Psychology StudiesMemory and Neural Mechanisms

Cited by 63

Annual Research Review: The (epi)genetics of neurodevelopmental disorders in the era of whole‐genome sequencing – unveiling the dark matter

Kiser, D. P., Rivero, O., & Lesch, K. (2015) · Journal of Child Psychology and Psychiatry

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 58

Genome‐wide analyses of aggressiveness in attention‐deficit hyperactivity disorder

Brevik, E. J., van Donkelaar, M. M. J., Weber, H., Sánchez‐Mora, C., Jacob, C., Rivero, O., Kittel‐Schneider, S., Garcia‐Martínez, I., Aebi, M., van Hulzen, K., et al. (2016) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 57

A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD

Jain, M., Vélez, J. I., Acosta, M. T., Palacio, L. G., Balog, J., Roessler, E., Pineda, D., Londoño, A. C., Palacio, J. D., Arbelaez, A., et al. (2012) · Molecular Psychiatry

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 57

5-HTT deficiency affects neuroplasticity and increases stress sensitivity resulting in altered spatial learning performance in the Morris water maze but not in the Barnes maze

Karabeg, M. M., Grauthoff, S., Kollert, S. Y., Weidner, M., Heiming, R. S., Jansen, F., Popp, S., Kaiser, S., Lesch, K.-P., Sachser, N., et al. (2013) · PLoS ONE

Memory and Neural MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 56

An international multicenter association study of the serotonin transporter gene in persistent ADHD

Landaas, E. T., Johansson, S., Jacobsen, K. K., Ribasés, M., Bosch, R., Sánchez‐Mora, C., Jacob, C. P., Boreatti‐Hümmer, A., Kreiker, S., Lesch, K. ‐., et al. (2010) · Genes, Brain and Behavior

Attention Deficit Hyperactivity DisorderNeurotransmitter Receptor Influence on Behavior

Cited by 55

Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder

Demontis, D., Walters, R. K., Rajagopal, V. M., Waldman, I. D., Grove, J., Als, T. D., Dalsgaard, S., Ribasés, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., et al. (2021) · Nature Communications

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 50

The DNA methylome in panic disorder: A case-control and longitudinal psychotherapy-epigenetic study

Ziegler, C., Grundner-Culemann, F., Schiele, M. A., Schlosser, P., Kollert, L., Mahr, M., Gajewska, A., Lesch, K.-P., Deckert, J., Köttgen, A., et al. (2019) · Translational Psychiatry

Epigenetics and DNA MethylationAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 47

Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life

Kriegebaum, C., Song, N.-N., Gutknecht, L., Huang, Y., Schmitt, A., Reif, A., Ding, Y.-Q., & Lesch, K.-P. (2010) · Neurochemistry International

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 45

Sex- and Subtype-Related Differences in the Comorbidity of Adult ADHDs

Groß-Lesch, S., Dempfle, A., Reichert, S., Jans, T., Geissler, J., Kittel-Schneider, S., Nguyen, T. T., Reif, A., Lesch, K.-P., & Jacob, C. P. (2016) · Journal of Attention Disorders

Attention Deficit Hyperactivity DisorderSubstance Abuse Treatment and Outcomes

Cited by 40

The involvement of the canonical Wnt‐signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta‐analysis

Grünblatt, E., Nemoda, Z., Werling, A. M., Roth, A., Angyal, N., Tarnok, Z., Thomsen, H., Peters, T., Hinney, A., Hebebrand, J., et al. (2019) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 32

Autonomic hypoactivity in boys with attention-deficit/hyperactivity disorder and the influence of methylphenidate

Conzelmann, A., Gerdes, A. B. M., Mucha, R. F., Weyers, P., Lesch, K.-P., Bähne, C. G., Fallgatter, A. J., Renner, T. J., Warnke, A., Romanos, M., et al. (2014) · The World Journal of Biological Psychiatry

Attention Deficit Hyperactivity DisorderAutism Spectrum Disorder Research

Cited by 29

Methylphenidate normalizes emotional processing in adult patients with attention-deficit/hyperactivity disorder: Preliminary findings

Conzelmann, A., Woidich, E., Mucha, R. F., Weyers, P., Jacob, C. P., Lesch, K.-P., & Pauli, P. (2011) · Brain Research

Attention Deficit Hyperactivity DisorderNeurotransmitter Receptor Influence on Behavior

Cited by 27

Hypermethylation of the serotonin transporter gene promoter in panic disorder-Epigenetic imprint of comorbid depression?

Schiele, M. A., Kollert, L., Lesch, K.-P., Arolt, V., Zwanzger, P., Deckert, J., Ziegler, C., & Domschke, K. (2019) · European Neuropsychopharmacology

Epigenetics and DNA MethylationAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 26

Rare genetic variants confer a high risk of ADHD and implicate neuronal biology

Demontis, D., Duan, J., Hsu, Y.-H. H., Pintacuda, G., Grove, J., Nielsen, T. T., Thirstrup, J., Martorana, M., Botts, T., Satterstrom, F. K., et al. (2026) · Nature

Attention Deficit Hyperactivity DisorderGenetics and Neurodevelopmental Disorders

Cited by 17

Maturing insights into the genetic architecture of neurodevelopmental disorders─from common and rare variant interplay to precision psychiatry

Lesch, K. (2016) · Journal of Child Psychology and Psychiatry

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 12