Lesch, Klaus-Peter

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

Lesch, K.-P., Bengel, D., Heils, A., Sabol, S. Z., Greenberg, B. D., Petri, S., Benjamin, J., Müller, C. R., Hamer, D. H., & Murphy, D. L. (1996) · Science

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 5,162

Allelic Variation of Human Serotonin Transporter Gene Expression

Heils, A., Teufel, A., Petri, S., Stöber, G., Riederer, P., Bengel, D., & Lesch, K. P. (1996) · Journal of Neurochemistry

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 2,221

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Demontis, D., Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., Baldursson, G., et al. (2019) · Nature Genetics

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 2,203

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., et al. (2018) · Science

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,924

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

Long story short: the serotonin transporter in emotion regulation and social cognition

Canli, T., & Lesch, K.-P. (2007) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 1,034

Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis

Hoogman, M., Bralten, J., Hibar, D. P., Mennes, M., Zwiers, M. P., Schweren, L. S. J., van Hulzen, K. J. E., Medland, S. E., Shumskaya, E., Jahanshad, N., et al. (2017) · The Lancet Psychiatry

Attention Deficit Hyperactivity DisorderNeural and Behavioral Psychology Studies

Cited by 879

Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan

Franke, B., Michelini, G., Asherson, P., Banaschewski, T., Bilbow, A., Buitelaar, J. K., Cormand, B., Faraone, S. V., Ginsberg, Y., Haavik, J., et al. (2018) · European Neuropsychopharmacology

Attention Deficit Hyperactivity DisorderChild and Adolescent Psychosocial and Emotional Development

Cited by 643

Neural stem cell proliferation is decreased in schizophrenia, but not in depression

Reif, A., Fritzen, S., Finger, M., Strobel, A., Lauer, M., Schmitt, A., & Lesch, K.-P. (2006) · Molecular Psychiatry

Neurogenesis and neuroplasticity mechanismsSchizophrenia research and treatment

Cited by 630

Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder

Deckert, J., Catalano, M., Syagailo, Y. V., Bosi, M., Okladnova, O., Di Bella, D., Nothen, M. M., Maffei, P., Franke, P., Fritze, J., et al. (1999) · Human Molecular Genetics

Neurotransmitter Receptor Influence on BehaviorAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 582

Targeting the murine serotonin transporter: insights into human neurobiology

Murphy, D. L., & Lesch, K.-P. (2008) · Nature Reviews Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 478

Brain imaging of the cortex in ADHD: a coordinated analysis of large-scale clinical and population-based samples

Hoogman, M., Muetzel, R., Guimaraes, J. P., Shumskaya, E., Mennes, M., Zwiers, M. P., Jahanshad, N., Sudre, G., Wolfers, T., Earl, E. A., et al. (2019) · American Journal of Psychiatry

Attention Deficit Hyperactivity DisorderNeural and Behavioral Psychology Studies

Cited by 467

Meta-Analysis of Genome-Wide Association Studies of Attention-Deficit/Hyperactivity Disorder

Neale, B. M., Medland, S. E., Ripke, S., Asherson, P., Franke, B., Lesch, K.-P., Faraone, S. V., Nguyen, T. T., Schäfer, H., Holmans, P., et al. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 450

Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders

Lesch, K.-P., & Waider, J. (2012) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 435

The genetics of attention deficit/hyperactivity disorder in adults, a review

on behalf of the International Multicentre persistent ADHD CollaboraTion (IMpACT), Franke, B., Faraone, S. V., Asherson, P., Buitelaar, J., Bau, C. H. D., Ramos-Quiroga, J. A., Mick, E., Grevet, E. H., Johansson, S., et al. (2012) · Molecular Psychiatry

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 432

Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

Elia, J., Glessner, J. T., Wang, K., Takahashi, N., Shtir, C. J., Hadley, D., Sleiman, P. M. A., Zhang, H., Kim, C. E., Robison, R., et al. (2012) · Nature Genetics

Attention Deficit Hyperactivity DisorderGenomic variations and chromosomal abnormalities

Cited by 406

Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques

Barr, C. S., Newman, T. K., Shannon, C., Parker, C., Dvoskin, R. L., Becker, M. L., Schwandt, M., Champoux, M., Lesch, K. P., Goldman, D., et al. (2004) · Biological Psychiatry

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 385

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies

Lesch, K.-P., Timmesfeld, N., Renner, T. J., Halperin, R., Röser, C., Nguyen, T. T., Craig, D. W., Romanos, J., Heine, M., Meyer, J., et al. (2008) · Journal of Neural Transmission

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 374

Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice

Wellman, C. L., Izquierdo, A., Garrett, J. E., Martin, K. P., Carroll, J., Millstein, R., Lesch, K.-P., Murphy, D. L., & Holmes, A. (2007) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorMemory and Neural Mechanisms

Cited by 366

Genome-Wide Analysis of Copy Number Variants in Attention Deficit Hyperactivity Disorder: The Role of Rare Variants and Duplications at 15q13.3

Williams, N. M., Franke, B., Mick, E., Anney, R. J. L., Freitag, C. M., Gill, M., Thapar, A., O'Donovan, M. C., Owen, M. J., Holmans, P., et al. (2012) · American Journal of Psychiatry

Genomic variations and chromosomal abnormalitiesAttention Deficit Hyperactivity Disorder

Cited by 290

Epigenetic Regulation of the BDNF Gene: Implications for Psychiatric Disorders

Boulle, F., van den Hove, D. L. A., Jakob, S. B., Rutten, B. P., Hamon, M., van Os, J., Lesch, K.-P., Lanfumey, L., Steinbusch, H. W., & Kenis, G. (2012) · Molecular Psychiatry

Epigenetics and DNA MethylationNerve injury and regeneration

Cited by 282

Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment

Reif, A., Rösler, M., Freitag, C. M., Schneider, M., Eujen, A., Kissling, C., Wenzler, D., Jacob, C. P., Retz-Junginger, P., Thome, J., et al. (2007) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorPsychopathy, Forensic Psychiatry, Sexual Offending

Cited by 277

Neural Hyporesponsiveness and Hyperresponsiveness During Immediate and Delayed Reward Processing in Adult Attention-Deficit/Hyperactivity Disorder

Plichta, M. M., Vasic, N., Wolf, R. C., Lesch, K.-P., Brummer, D., Jacob, C., Fallgatter, A. J., & Grön, G. (2009) · Biological Psychiatry

Attention Deficit Hyperactivity DisorderNeural and Behavioral Psychology Studies

Cited by 272

Co-morbidity of adult attention-deficit/hyperactivity disorder with focus on personality traits and related disorders in a tertiary referral center

Jacob, C. P., Romanos, J., Dempfle, A., Heine, M., Windemuth-Kieselbach, C., Kruse, A., Reif, A., Walitza, S., Romanos, M., Strobel, A., et al. (2007) · European Archives of Psychiatry and Clinical Neuroscience

Attention Deficit Hyperactivity DisorderPersonality Disorders and Psychopathology

Cited by 237