Penzes, Peter

Dendritic spine pathology in neuropsychiatric disorders

Penzes, P., Cahill, M. E., Jones, K. A., VanLeeuwen, J.-E., & Woolfrey, K. M. (2011) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 1,523

Common Mechanisms of Excitatory and Inhibitory Imbalance in Schizophrenia and Autism Spectrum Disorders

Gao, R., & Penzes, P. (2015) · Current Molecular Medicine

Neuroscience and Neuropharmacology ResearchSchizophrenia research and treatment

Cited by 516

Rapid Induction of Dendritic Spine Morphogenesis by trans-Synaptic EphrinB-EphB Receptor Activation of the Rho-GEF Kalirin

Penzes, P., Beeser, A., Chernoff, J., Schiller, M. R., Eipper, B. A., Mains, R. E., & Huganir, R. L. (2003) · Neuron

Axon Guidance and Neuronal SignalingNeuroscience and Neuropharmacology Research

Cited by 466

Dendritic structural plasticity and neuropsychiatric disease

Forrest, M. P., Parnell, E., & Penzes, P. (2018) · Nature Reviews Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 464

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

Hayashi-Takagi, A., Takaki, M., Graziane, N., Seshadri, S., Murdoch, H., Dunlop, A. J., Makino, Y., Seshadri, A. J., Ishizuka, K., Srivastava, D. P., et al. (2010) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchSchizophrenia research and treatment

Cited by 399

Kalirin-7 Controls Activity-Dependent Structural and Functional Plasticity of Dendritic Spines

Xie, Z., Srivastava, D. P., Photowala, H., Kai, L., Cahill, M. E., Woolfrey, K. M., Shum, C. Y., Surmeier, D. J., & Penzes, P. (2007) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 373

Rapid modulation of spine morphology by the 5-HT 2A serotonin receptor through kalirin-7 signaling

Jones, K. A., Srivastava, D. P., Allen, J. A., Strachan, R. T., Roth, B. L., & Penzes, P. (2009) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 226

Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes

Cahill, M. E., Xie, Z., Day, M., Photowala, H., Barbolina, M. V., Miller, C. A., Weiss, C., Radulovic, J., Sweatt, J. D., Disterhoft, J. F., et al. (2009) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 170

Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines

Woolfrey, K. M., Srivastava, D. P., Photowala, H., Yamashita, M., Barbolina, M. V., Cahill, M. E., Xie, Z., Jones, K. A., Quilliam, L. A., Prakriya, M., et al. (2009) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 161

Dendritic spine dynamics--a key role for kalirin-7

Penzes, P., & Jones, K. A. (2008) · Trends in Neurosciences

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 157

Segregated populations of hippocampal principal CA1 neurons mediating conditioning and extinction of contextual fear

Tronson, N. C., Schrick, C., Guzman, Y. F., Huh, K. H., Srivastava, D. P., Penzes, P., Guedea, A. L., Gao, C., & Radulovic, J. (2009) · The Journal of Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 136

Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders

Penzes, P., Buonanno, A., Passafaro, M., Sala, C., & Sweet, R. A. (2013) · Journal of Neurochemistry

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 125

Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub

Blizinsky, K. D., Diaz-Castro, B., Forrest, M. P., Schürmann, B., Bach, A. P., Martin-de-Saavedra, M. D., Wang, L., Csernansky, J. G., Duan, J., & Penzes, P. (2016) · Proceedings of the National Academy of Sciences

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 76

A novel role for the late-onset Alzheimer’s disease (LOAD)-associated protein Bin1 in regulating postsynaptic trafficking and glutamatergic signaling

Schürmann, B., Bermingham, D. P., Kopeikina, K. J., Myczek, K., Yoon, S., Horan, K. E., Kelly, C. J., Martin-de-Saavedra, M. D., Forrest, M. P., Fawcett-Patel, J. M., et al. (2020) · Molecular Psychiatry

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 72

Kalirin loss results in cortical morphological alterations

Xie, Z., Cahill, M. E., & Penzes, P. (2010) · Molecular and Cellular Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 56

Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development

Fraser, J., Essebier, A., Brown, A. S., Davila, R. A., Harkins, D., Zalucki, O., Shapiro, L. P., Penzes, P., Wainwright, B. J., Scott, M. P., et al. (2020) · The Cerebellum

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 46

Hippocampal phenotypes in kalirin-deficient mice

Xie, Z., Cahill, M. E., Radulovic, J., Wang, J., Campbell, S. L., Miller, C. A., Sweatt, J. D., & Penzes, P. (2011) · Molecular and Cellular Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 34

Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons

Zhang, S., Zhang, H., Forrest, M. P., Zhou, Y., Sun, X., Bagchi, V. A., Kozlova, A., Santos, M. D., Piguel, N. H., Dionisio, L. E., et al. (2023) · Cell Genomics

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 26