Groop, Leif

Link between GIP and osteopontin in adipose tissue and insulin resistance

Ahlqvist, E., Osmark, P., Kuulasmaa, T., Pilgaard, K., Omar, B., Brøns, C., Kotova, O., Zetterqvist, A. V., Stančáková, A., Jonsson, A., et al. (2013) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesBone Metabolism and Diseases

Cited by 96

Comparing strategies to fine-map the association of common SNPs at chromosome 9p21 with type 2 diabetes and myocardial infarction

The Myocardial Infarction Genetics Consortium, Shea, J., Agarwala, V., Philippakis, A. A., Maguire, J., Banks, E., DePristo, M., Thomson, B., Guiducci, C., Onofrio, R. C., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 87

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes

Xie, W., Wood, A. R., Lyssenko, V., Weedon, M. N., Knowles, J. W., Alkayyali, S., Assimes, T. L., Quertermous, T., Abbasi, F., Paananen, J., et al. (2013) · Diabetes

Genetic Associations and EpidemiologyMetabolomics and Mass Spectrometry Studies

Cited by 83

Classifying diabetes according to the new WHO clinical stages

Lindholm, E., Agardh, E., Tuomi, T., Groop, L., & Agardh, C.-D. (2001) · European Journal of Epidemiology

Diabetes and associated disordersDiabetes Management and Research

Cited by 82

Validation of the classification for type 2 diabetes into five subgroups: a report from the ORIGIN trial

Pigeyre, M., Hess, S., Gomez, M. F., Asplund, O., Groop, L., Paré, G., & Gerstein, H. (2022) · Diabetologia

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 79

Short-term exercise training does not stimulate skeletal muscle ATP synthesis in relatives of humans with type 2 diabetes.

Kacerovsky-Bielesz, G., Chmelik, M., Ling, C., Pokan, R., Szendroedi, J., Farukuoye, M., Kacerovsky, M., Schmid, A. I., Gruber, S., Wolzt, M., et al. (2009) · Diabetes

Metabolism, Diabetes, and CancerCardiovascular and exercise physiology

Cited by 75

Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in type 2 diabetes

Tripathy, D., Eriksson, K. F., Orho-Melander, M., Fredriksson, J., Ahlqvist, G., & Groop, L. (2004) · Diabetologia

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 74

Importance of Obtaining Independent Measures of Insulin Secretion and Insulin Sensitivity During the Same Test

Tripathy, D., Wessman, Y., Gullström, M., Tuomi, T., & Groop, L. (2003) · Diabetes Care

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 74

An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics

Tura, A., Sbrignadello, S., Succurro, E., Groop, L., Sesti, G., & Pacini, G. (2010) · Diabetologia

Diabetes, Cardiovascular Risks, and LipoproteinsPancreatic function and diabetes

Cited by 71

Protein biomarkers for the prediction of cardiovascular disease in type 2 diabetes

on behalf of the SUMMIT Investigators, Looker, H. C., Colombo, M., Agakov, F., Zeller, T., Groop, L., Thorand, B., Palmer, C. N., Hamsten, A., de Faire, U., et al. (2015) · Diabetologia

Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic Diseases

Cited by 66

Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

Lim, E. T., Würtz, P., Havulinna, A. S., Palta, P., Tukiainen, T., Rehnström, K., Esko, T., Mägi, R., Inouye, M., Lappalainen, T., et al. (2014) · PLoS Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 49

Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC

Mishra, R., Åkerlund, M., Cousminer, D. L., Ahlqvist, E., Bradfield, J. P., Chesi, A., Hodge, K. M., Guy, V. C., Brillon, D. J., Pratley, R. E., et al. (2020) · Diabetes Care

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 46

Isolation and Characterization of the Human Muscle Glycogen Synthase Gene

Orho, M., Nikula-Ijäs, P., Schalin-Jäntti, C., Permutt, M. A., & Groop, L. C. (1995) · Diabetes

Glycogen Storage Diseases and MyoclonusMetabolism, Diabetes, and Cancer

Cited by 45

MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes

Ganic, E., Singh, T., Luan, C., Fadista, J., Johansson, J. K., Cyphert, H. A., Bennet, H., Storm, P., Prost, G., Ahlenius, H., et al. (2016) · Cell Reports

Pancreatic function and diabetesNicotinic Acetylcholine Receptors Study

Cited by 41

Effect of sulphonylurea on glucose-stimulated insulin secretion in healthy and non-insulin dependent diabetic subjects: a dose-response study

Groop, L. C., Ratheiser, K., Luzi, L., Melander, A., Simonson, D. C., Petrides, A., Bonadonna, R. C., Wid�n, E., & DeFronzo, R. A. (1991) · Acta Diabetologica

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 39

Molecular correlates for maximal oxygen uptake and type 1 fibers

Parikh, H., Nilsson, E., Ling, C., Poulsen, P., Almgren, P., Nittby, H., Eriksson, K.-F., Vaag, A., & Groop, L. C. (2008) · American Journal of Physiology-Endocrinology and Metabolism

Cardiovascular and exercise physiologyGenetics and Physical Performance

Cited by 36

Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins

Rönn, T., Poulsen, P., Tuomi, T., Isomaa, B., Groop, L., Vaag, A., & Ling, C. (2009) · PLoS ONE

Metabolism, Diabetes, and CancerGenetic Associations and Epidemiology

Cited by 36

Use of Swedish smokeless tobacco (snus) and the risk of Type 2 diabetes and latent autoimmune diabetes of adulthood (LADA)

Rasouli, B., Andersson, T., Carlsson, P. ‐., Grill, V., Groop, L., Martinell, M., Midthjell, K., Storm, P., Tuomi, T., & Carlsson, S. (2017) · Diabetic Medicine

Smoking Behavior and CessationDiabetes and associated disorders

Cited by 24

Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity

Lehto, M., Huang, X., Davis, E. M., Le Beau, M. M., Laurila, E., Eriksson, K. F., Bell, G. I., & Groop, L. (1995) · Diabetologia

Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus

Cited by 22

What do healthcare professionals need to turn risk models for type 2 diabetes into usable computerized clinical decision support systems? Lessons learned from the MOSAIC project

Fico, G., Hernanzez, L., Cancela, J., Dagliati, A., Sacchi, L., Martinez-Millana, A., Posada, J., Manero, L., Verdú, J., Facchinetti, A., et al. (2019) · BMC Medical Informatics and Decision Making

Electronic Health Records SystemsTechnology and Human Factors in Education and Health

Cited by 22

Familiality of metabolic abnormalities is dependent on age at onset and phenotype of the type 2 diabetic proband

Tripathy, D., Lindholm, E., Isomaa, B., Saloranta, C., Tuomi, T., & Groop, L. (2003) · American Journal of Physiology-Endocrinology and Metabolism

Diabetes, Cardiovascular Risks, and LipoproteinsPancreatic function and diabetes

Cited by 20