Kasper, Dennis L.

An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System

Mazmanian, S. K., Liu, C. H., Tzianabos, A. O., & Kasper, D. L. (2005) · Cell

Gut microbiota and healthImmune Response and Inflammation

Cited by 2,910

A microbial symbiosis factor prevents intestinal inflammatory disease

Mazmanian, S. K., Round, J. L., & Kasper, D. L. (2008) · Nature

Gut microbiota and healthInflammatory Bowel Disease

Cited by 2,340

How colonization by microbiota in early life shapes the immune system

Gensollen, T., Iyer, S. S., Kasper, D. L., & Blumberg, R. S. (2016) · Science

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 2,044

Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

Olszak, T., An, D., Zeissig, S., Vera, M. P., Richter, J., Franke, A., Glickman, J. N., Siebert, R., Baron, R. M., Kasper, D. L., et al. (2012) · Science

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 1,661

Gut immune maturation depends on colonization with a host-specific microbiota

Chung, H., Pamp, S. J., Hill, J. A., Surana, N. K., Edelman, S. M., Troy, E. B., Reading, N. C., Villablanca, E. J., Wang, S., Mora, J. R., et al. (2012) · Cell

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 1,241

Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis

Song, X., Sun, X., Oh, S. F., Wu, M., Zhang, Y., Zheng, W., Geva-Zatorsky, N., Jupp, R., Mathis, D., Benoist, C., et al. (2020) · Nature

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 1,024

Individual intestinal symbionts induce a distinct population of RORγ + regulatory T cells

Sefik, E., Geva-Zatorsky, N., Oh, S., Konnikova, L., Zemmour, D., McGuire, A. M., Burzyn, D., Ortiz-Lopez, A., Lobera, M., Yang, J., et al. (2015) · Science

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 879

A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip

Jalili-Firoozinezhad, S., Gazzaniga, F. S., Calamari, E. L., Camacho, D. M., Fadel, C. W., Bein, A., Swenor, B., Nestor, B., Cronce, M. J., Tovaglieri, A., et al. (2019) · Nature Biomedical Engineering

Gut microbiota and health3D Printing in Biomedical Research

Cited by 855

Mining the Human Gut Microbiota for Immunomodulatory Organisms

Geva-Zatorsky, N., Sefik, E., Kua, L., Pasman, L., Tan, T. G., Ortiz-Lopez, A., Yanortsang, T. B., Yang, L., Jupp, R., Mathis, D., et al. (2017) · Cell

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 762

Sphingolipids from a Symbiotic Microbe Regulate Homeostasis of Host Intestinal Natural Killer T Cells

An, D., Oh, S. F., Olszak, T., Neves, J. F., Avci, F. Y., Erturk-Hasdemir, D., Lu, X., Zeissig, S., Blumberg, R. S., & Kasper, D. L. (2014) · Cell

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 643

Identification of a Universal Group B Streptococcus Vaccine by Multiple Genome Screen

Maione, D., Margarit, I., Rinaudo, C. D., Masignani, V., Mora, M., Scarselli, M., Tettelin, H., Brettoni, C., Iacobini, E. T., Rosini, R., et al. (2005) · Science

Neonatal and Maternal InfectionsBacterial Infections and Vaccines

Cited by 556

A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

Ochoa-Repáraz, J., Mielcarz, D. W., Wang, Y., Begum-Haque, S., Dasgupta, S., Kasper, D. L., & Kasper, L. H. (2010) · Mucosal Immunology

Multiple Sclerosis Research StudiesT-cell and B-cell Immunology

Cited by 507

Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice

Tan, T. G., Sefik, E., Geva-Zatorsky, N., Kua, L., Naskar, D., Teng, F., Pasman, L., Ortiz-Lopez, A., Jupp, R., Wu, H.-J. J., et al. (2016) · Proceedings of the National Academy of Sciences

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 427

Central Nervous System Demyelinating Disease Protection by the Human Commensal Bacteroides fragilis Depends on Polysaccharide A Expression

Ochoa-Repáraz, J., Mielcarz, D. W., Ditrio, L. E., Burroughs, A. R., Begum-Haque, S., Dasgupta, S., Kasper, D. L., & Kasper, L. H. (2010) · The Journal of Immunology

Multiple Sclerosis Research StudiesT-cell and B-cell Immunology

Cited by 367

Polysaccharide processing and presentation by the MHCII pathway

Cobb, B. A., Wang, Q., Tzianabos, A. O., & Kasper, D. L. (2004) · Cell

Immunotherapy and Immune ResponsesImmune Response and Inflammation

Cited by 340

Plasmacytoid dendritic cells mediate anti-inflammatory responses to a gut commensal molecule via both innate and adaptive mechanisms

Dasgupta, S., Erturk-Hasdemir, D., Ochoa-Reparaz, J., Reinecker, H.-C., & Kasper, D. L. (2014) · Cell Host & Microbe

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 292

Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules

Cress, B. F., Englaender, J. A., He, W., Kasper, D., Linhardt, R. J., & Koffas, M. A. G. (2014) · FEMS Microbiology Reviews

Escherichia coli research studiesBacterial Infections and Vaccines

Cited by 282

Oxidative depolymerization of polysaccharides by reactive oxygen/nitrogen species

Duan, J., & Kasper, D. L. (2011) · Glycobiology

Redox biology and oxidative stressPolysaccharides Composition and Applications

Cited by 267

A commensal symbiotic factor derived from Bacteroides fragilis promotes human CD39 + Foxp3 + T cells and T reg function

Telesford, K. M., Yan, W., Ochoa-Reparaz, J., Pant, A., Kircher, C., Christy, M. A., Begum-Haque, S., Kasper, D. L., & Kasper, L. H. (2015) · Gut Microbes

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 252

An intestinal organ culture system uncovers a role for the nervous system in microbe-immune crosstalk

Yissachar, N., Zhou, Y., Ung, L., Lai, N. Y., Mohan, J. F., Ehrlicher, A., Weitz, D. A., Kasper, D. L., Chiu, I. M., Mathis, D., et al. (2017) · Cell

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 242

Targeting PD-L2–RGMb overcomes microbiome-related immunotherapy resistance

Park, J. S., Gazzaniga, F. S., Wu, M., Luthens, A. K., Gillis, J., Zheng, W., LaFleur, M. W., Johnson, S. B., Morad, G., Park, E. M., et al. (2023) · Nature

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 191

Bacteroides fragilis polysaccharide A is necessary and sufficient for acute activation of intestinal sensory neurons

Mao, Y.-K., Kasper, D. L., Wang, B., Forsythe, P., Bienenstock, J., & Kunze, W. A. (2013) · Nature Communications

Gastrointestinal motility and disordersProbiotics and Fermented Foods

Cited by 178

Microbiota-targeted maternal antibodies protect neonates from enteric infection

Zheng, W., Zhao, W., Wu, M., Song, X., Caro, F., Sun, X., Gazzaniga, F., Stefanetti, G., Oh, S., Mekalanos, J. J., et al. (2020) · Nature

Escherichia coli research studiesMonoclonal and Polyclonal Antibodies Research

Cited by 158

Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.

Henneke, P., Takeuchi, O., Malley, R., Lien, E., Ingalls, R. R., Freeman, M. W., Mayadas, T., Nizet, V., Akira, S., Kasper, D. L., et al. (2002) · The Journal of Immunology

Immune Response and InflammationNeonatal and Maternal Infections

Cited by 145