Kroemer, Guido

Metabolic Control of Longevity

López-Otín, C., Galluzzi, L., Freije, J. M. P., Madeo, F., & Kroemer, G. (2016) · Cell

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 753

Mitochondria: master regulators of danger signalling

Galluzzi, L., Kepp, O., & Kroemer, G. (2012) · Nature Reviews Molecular Cell Biology

Mitochondrial Function and PathologyImmune Response and Inflammation

Cited by 733

Hallmarks of T cell aging

Mittelbrunn, M., & Kroemer, G. (2021) · Nature Immunology

T-cell and B-cell ImmunologyGenetics, Aging, and Longevity in Model Organisms

Cited by 702

Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer

Derosa, L., Routy, B., Thomas, A. M., Iebba, V., Zalcman, G., Friard, S., Mazieres, J., Audigier-Valette, C., Moro-Sibilot, D., Goldwasser, F., et al. (2022) · Nature Medicine

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 685

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice

Bárcena, C., Valdés-Mas, R., Mayoral, P., Garabaya, C., Durand, S., Rodríguez, F., Fernández-García, M. T., Salazar, N., Nogacka, A. M., Garatachea, N., et al. (2019) · Nature Medicine

Gut microbiota and healthGenetics, Aging, and Longevity in Model Organisms

Cited by 661

Dendritic cell-derived exosomes for cancer therapy.

Pitt, J. M., André, F., Amigorena, S., Soria, J.-C., Eggermont, A., Kroemer, G., & Zitvogel, L. (2016) · Journal of Clinical Investigation

Immunotherapy and Immune ResponsesExtracellular vesicles in disease

Cited by 636

Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential

Madeo, F., Carmona-Gutierrez, D., Hofer, S. J., & Kroemer, G. (2019) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 630

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

Morselli, E., Maiuri, M. C., Markaki, M., Megalou, E., Pasparaki, A., Palikaras, K., Criollo, A., Galluzzi, L., Malik, S. A., Vitale, I., et al. (2010) · Cell Death & Disease

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 613

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein

Dai, E., Han, L., Liu, J., Xie, Y., Kroemer, G., Klionsky, D. J., Zeh, H. J., Kang, R., Wang, J., & Tang, D. (2020) · Autophagy

Immune cells in cancerFerroptosis and cancer prognosis

Cited by 613

Inflammasomes in carcinogenesis and anticancer immune responses

Zitvogel, L., Kepp, O., Galluzzi, L., & Kroemer, G. (2012) · Nature Immunology

Inflammasome and immune disordersImmune cells in cancer

Cited by 593

Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis

Deniaud, A., Sharaf el dein, O., Maillier, E., Poncet, D., Kroemer, G., Lemaire, C., & Brenner, C. (2008) · Oncogene

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 586

The hallmarks of successful anticancer immunotherapy

Galluzzi, L., Chan, T. A., Kroemer, G., Wolchok, J. D., & López-Soto, A. (2018) · Science Translational Medicine

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 575

Molecular mechanisms of ATP secretion during immunogenic cell death

Martins, I., Wang, Y., Michaud, M., Ma, Y., Sukkurwala, A. Q., Shen, S., Kepp, O., Métivier, D., Galluzzi, L., Perfettini, J.-L., et al. (2014) · Cell Death & Differentiation

Cell death mechanisms and regulationAdenosine and Purinergic Signaling

Cited by 563

Necroptosis: A Specialized Pathway of Programmed Necrosis

Galluzzi, L., & Kroemer, G. (2008) · Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 561

Decoding Cell Death Signals in Inflammation and Immunity

Zitvogel, L., Kepp, O., & Kroemer, G. (2010) · Cell

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 558

Caloric restriction mimetics enhance anticancer immunosurveillance

Pietrocola, F., Pol, J., Vacchelli, E., Rao, S., Enot, D. P., Baracco, E. E., Levesque, S., Castoldi, F., Jacquelot, N., Yamazaki, T., et al. (2016) · Cancer Cell

Autophagy in Disease and TherapyDietary Effects on Health

Cited by 542

Anticancer effects of the microbiome and its products

Zitvogel, L., Daillère, R., Roberti, M. P., Routy, B., & Kroemer, G. (2017) · Nature Reviews Microbiology

Gut microbiota and healthBacterial Cancer Therapy

Cited by 538

Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade

Ferrere, G., Tidjani Alou, M., Liu, P., Goubet, A.-G., Fidelle, M., Kepp, O., Durand, S., Iebba, V., Fluckiger, A., Daillère, R., et al. (2021) · JCI Insight

Diet and metabolism studiesCancer Immunotherapy and Biomarkers

Cited by 533

Meta-hallmarks of aging and cancer

López-Otín, C., Pietrocola, F., Roiz-Valle, D., Galluzzi, L., & Kroemer, G. (2023) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 529

The gut microbiota influences anticancer immunosurveillance and general health

Routy, B., Gopalakrishnan, V., Daillère, R., Zitvogel, L., Wargo, J. A., & Kroemer, G. (2018) · Nature Reviews Clinical Oncology

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 523

Regulation of autophagy by cytosolic acetyl-coenzyme A

Mariño, G., Pietrocola, F., Eisenberg, T., Kong, Y., Malik, S. A., Andryushkova, A., Schroeder, S., Pendl, T., Harger, A., Niso-Santano, M., et al. (2014) · Molecular Cell

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 500

Hallmarks of Health

López-Otín, C., & Kroemer, G. (2021) · Cell

Genetics, Aging, and Longevity in Model OrganismsHealth, psychology, and well-being

Cited by 499

Targeting the gut and tumor microbiota in cancer

Park, E. M., Chelvanambi, M., Bhutiani, N., Kroemer, G., Zitvogel, L., & Wargo, J. A. (2022) · Nature Medicine

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 496

Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion

Boya, P., Andreau, K., Poncet, D., Zamzami, N., Perfettini, J.-L., Metivier, D., Ojcius, D. M., Jäättelä, M., & Kroemer, G. (2003) · The Journal of Experimental Medicine

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 483