Kroemer, Guido

Microbiome and Anticancer Immunosurveillance

Zitvogel, L., Ayyoub, M., Routy, B., & Kroemer, G. (2016) · Cell

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 478

Calreticulin exposure is required for the immunogenicity of γ-irradiation and UVC light-induced apoptosis

Obeid, M., Panaretakis, T., Joza, N., Tufi, R., Tesniere, A., van Endert, P., Zitvogel, L., & Kroemer, G. (2007) · Cell Death & Differentiation

Immunotherapy and Immune ResponsesCell death mechanisms and regulation

Cited by 474

Cancer and the gut microbiota: An unexpected link

Zitvogel, L., Galluzzi, L., Viaud, S., Vétizou, M., Daillère, R., Merad, M., & Kroemer, G. (2015) · Science Translational Medicine

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 465

Essential role for autophagy in life span extension

Madeo, F., Zimmermann, A., Maiuri, M. C., & Kroemer, G. (2015) · Journal of Clinical Investigation

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 464

Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1

Vacchelli, E., Ma, Y., Baracco, E. E., Sistigu, A., Enot, D. P., Pietrocola, F., Yang, H., Adjemian, S., Chaba, K., Semeraro, M., et al. (2015) · Science

Immunotherapy and Immune ResponsesChemokine receptors and signaling

Cited by 452

Autophagy and cellular immune responses

Ma, Y., Galluzzi, L., Zitvogel, L., & Kroemer, G. (2013) · Immunity

Autophagy in Disease and TherapyPhagocytosis and Immune Regulation

Cited by 447

Nutrition, inflammation and cancer

Zitvogel, L., Pietrocola, F., & Kroemer, G. (2017) · Nature Immunology

Immune cells in cancerNutritional Studies and Diet

Cited by 446

An Immunosurveillance Mechanism Controls Cancer Cell Ploidy

Senovilla, L., Vitale, I., Martins, I., Tailler, M., Pailleret, C., Michaud, M., Galluzzi, L., Adjemian, S., Kepp, O., Niso-Santano, M., et al. (2012) · Science

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 436

Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

Menger, L., Vacchelli, E., Adjemian, S., Martins, I., Ma, Y., Shen, S., Yamazaki, T., Sukkurwala, A. Q., Michaud, M., Mignot, G., et al. (2012) · Science Translational Medicine

Immunotherapy and Immune ResponsesCell death mechanisms and regulation

Cited by 423

Mitochondrial membrane permeabilization in neuronal injury

Galluzzi, L., Blomgren, K., & Kroemer, G. (2009) · Nature Reviews Neuroscience

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 418

Alternate day fasting improves physiological and molecular markers of aging in healthy, non-obese humans

Stekovic, S., Hofer, S. J., Tripolt, N., Aon, M. A., Royer, P., Pein, L., Stadler, J. T., Pendl, T., Prietl, B., Url, J., et al. (2019) · Cell Metabolism

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 412

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes

Pospisilik, J. A., Knauf, C., Joza, N., Benit, P., Orthofer, M., Cani, P. D., Ebersberger, I., Nakashima, T., Sarao, R., Neely, G., et al. (2007) · Cell

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 404

Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients

Derosa, L., Routy, B., Fidelle, M., Iebba, V., Alla, L., Pasolli, E., Segata, N., Desnoyer, A., Pietrantonio, F., Ferrere, G., et al. (2020) · European Urology

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 398

Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage

Fluckiger, A., Daillère, R., Sassi, M., Sixt, B. S., Liu, P., Loos, F., Richard, C., Rabu, C., Alou, M. T., Goubet, A.-G., et al. (2020) · Science

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 396

From geroscience to precision geromedicine: Understanding and managing aging

Kroemer, G., Maier, A. B., Cuervo, A. M., Gladyshev, V. N., Ferrucci, L., Gorbunova, V., Kennedy, B. K., Rando, T. A., Seluanov, A., Sierra, F., et al. (2025) · Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 395

Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondria

Jan, G., Belzacq, A.-S., Haouzi, D., Rouault, A., Métivier, D., Kroemer, G., & Brenner, C. (2002) · Cell Death & Differentiation

Cell death mechanisms and regulationProbiotics and Fermented Foods

Cited by 385

Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine

Boya, P., Gonzalez-Polo, R.-A., Poncet, D., Andreau, K., Vieira, H. L., Roumier, T., Perfettini, J.-L., & Kroemer, G. (2003) · Oncogene

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 385

Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity

Yang, H., Xia, L., Chen, J., Zhang, S., Martin, V., Li, Q., Lin, S., Chen, J., Calmette, J., Lu, M., et al. (2019) · Nature Medicine

Cancer, Stress, Anesthesia, and Immune ResponseStress Responses and Cortisol

Cited by 379

IL-18 Induces PD-1–Dependent Immunosuppression in Cancer

Terme, M., Ullrich, E., Aymeric, L., Meinhardt, K., Desbois, M., Delahaye, N., Viaud, S., Ryffel, B., Yagita, H., Kaplanski, G., et al. (2011) · Cancer Research

Immune Cell Function and InteractionCancer Immunotherapy and Biomarkers

Cited by 376

DNA Damage in Stem Cells

Vitale, I., Manic, G., De Maria, R., Kroemer, G., & Galluzzi, L. (2017) · Molecular Cell

DNA Repair MechanismsTelomeres, Telomerase, and Senescence

Cited by 361

Mitophagy: An Emerging Role in Aging and Age-Associated Diseases

Chen, G., Kroemer, G., & Kepp, O. (2020) · Frontiers in Cell and Developmental Biology

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 359

Spermidine induces autophagy by inhibiting the acetyltransferase EP300

Pietrocola, F., Lachkar, S., Enot, D. P., Niso-Santano, M., Bravo-San Pedro, J. M., Sica, V, Izzo, V, Maiuri, M. C., Madeo, F., Mariño, G., et al. (2015) · Cell Death & Differentiation

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 357

Caspases Connect Cell-Death Signaling to Organismal Homeostasis

Galluzzi, L., López-Soto, A., Kumar, S., & Kroemer, G. (2016) · Immunity

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 350

Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe

Castedo, M., Perfettini, J.-L., Roumier, T., & Kroemer, G. (2002) · Cell Death & Differentiation

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 345