Decoding Cell Death Signals in Inflammation and Immunity
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Dying cells release and expose at their surface molecules that signal to the immune system. We speculate that combinations of these molecules determine the route by which dying cells are engulfed and the nature of the immune response that their death elicits.
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Many DAMPs are generated by cancer cells in response to chemotherapeutic drugs such as DXR and cyclophosphamide.
“Many DAMPS are generated by cancer cells in response to chemotherapeutic drugs such as DXR and cyclophosphamide [43].”
From Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells (2016) · cites this paper as [43]
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- Authors
- Zitvogel, L., Kepp, O., & Kroemer, G.
- Affiliations
- Université Paris-Sud (FR)
- Corresponding author
- Zitvogel, Laurence
- Kroemer, Guido
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 140
- Issue
- 6
- Pages
- 798-804
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W1993877349
- Cited by
- 558
- References
- 14
- Citations by year
- 2026: 6 · 2025: 15 · 2024: 21 · 2023: 16 · 2022: 19 · 2021: 29 · 2020: 41 · 2019: 30 · 2018: 22 · 2017: 30 · 2016: 42 · 2015: 53 · 2014: 52 · 2013: 53 · 2012: 54
- FWCI
- 24.78
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Fondation pour la Recherche Médicale
- Ligue Contre le Cancer
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Phagocytosis and Immune Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cell death mechanisms and regulation
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Keywords
- cell death, inflammation, immunity, extracellular vesicles, phagocytosis, immune response, cell surface molecules
- MeSH terms
- Animals, Autophagy, Endoplasmic Reticulum, Humans, Immunity, Inflammation, Stress, Physiological, Cellular Senescence, Cell Death
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