Kroemer, Guido

The breakthrough of the microbiota

Kroemer, G., & Zitvogel, L. (2018) · Nature Reviews Immunology

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 147

Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos

Vitale, I., Senovilla, L., Jemaà, M., Michaud, M., Galluzzi, L., Kepp, O., Nanty, L., Criollo, A., Rello‐Varona, S., Manic, G., et al. (2010) · The EMBO Journal

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

Cited by 146

hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway

Massard, C., Zermati, Y., Pauleau, A.-L., Larochette, N., Métivier, D., Sabatier, L., Kroemer, G., & Soria, J.-C. (2006) · Oncogene

Cell death mechanisms and regulationTelomeres, Telomerase, and Senescence

Cited by 144

Immunological off-target effects of imatinib

Zitvogel, L., Rusakiewicz, S., Routy, B., Ayyoub, M., & Kroemer, G. (2016) · Nature Reviews Clinical Oncology

Chronic Myeloid Leukemia TreatmentsGastrointestinal Tumor Research and Treatment

Cited by 142

A Novel Epidermal Growth Factor Receptor Inhibitor Promotes Apoptosis in Non–Small Cell Lung Cancer Cells Resistant to Erlotinib

de La Motte Rouge, T., Galluzzi, L., Olaussen, K. A., Zermati, Y., Tasdemir, E., Robert, T., Ripoche, H., Lazar, V., Dessen, P., Harper, F., et al. (2007) · Cancer Research

Lung Cancer Treatments and MutationsHER2/EGFR in Cancer Research

Cited by 141

Gut OncoMicrobiome Signatures (GOMS) as next-generation biomarkers for cancer immunotherapy

Thomas, A. M., Fidelle, M., Routy, B., Kroemer, G., Wargo, J. A., Segata, N., & Zitvogel, L. (2023) · Nature Reviews Clinical Oncology

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 141

The life span-prolonging effect of Sirtuin-1 is mediated by autophagy

Morselli, E., Maiuri, M. C., Markaki, M., Megalou, E., Pasparaki, A., Palikaras, K., Criollo, A., Galluzzi, L., Malik, S. A., Vitale, I., et al. (2010) · Autophagy

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 139

Tumor-Infiltrating Regulatory T Cells: Phenotype, Role, Mechanism of Expansion In Situ and Clinical Significance

Tanchot, C., Terme, M., Pere, H., Tran, T., Benhamouda, N., Strioga, M., Banissi, C., Galluzzi, L., Kroemer, G., & Tartour, E. (2013) · Cancer Microenvironment

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 138

Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

Buqué, A., Bloy, N., Perez-Lanzón, M., Iribarren, K., Humeau, J., Pol, J. G., Levesque, S., Mondragon, L., Yamazaki, T., Sato, A., et al. (2020) · Nature Communications

Cancer Immunotherapy and BiomarkersBreast Cancer Treatment Studies

Cited by 138

Autophagy-dependent ATP release from dying cells via lysosomal exocytosis

Wang, Y., Martins, I., Ma, Y., Kepp, O., Galluzzi, L., & Kroemer, G. (2013) · Autophagy

Autophagy in Disease and TherapyAdenosine and Purinergic Signaling

Cited by 137

Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

Fucikova, J., Truxova, I., Hensler, M., Becht, E., Kasikova, L., Moserova, I., Vosahlikova, S., Klouckova, J., Church, S. E., Cremer, I., et al. (2016) · Blood

Acute Myeloid Leukemia ResearchImmunotherapy and Immune Responses

Cited by 135

A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis

Büttner, S., Ruli, D., Vögtle, F., Galluzzi, L., Moitzi, B., Eisenberg, T., Kepp, O., Habernig, L., Carmona‐Gutierrez, D., Rockenfeller, P., et al. (2011) · The EMBO Journal

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 133

Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

Chondronasiou, D., Gill, D., Mosteiro, L., Urdinguio, R. G., Berenguer‐Llergo, A., Aguilera, M., Durand, S., Aprahamian, F., Nirmalathasan, N., Abad, M., et al. (2022) · Aging Cell

Pluripotent Stem Cells ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 133

The effects of p53 on whole organism longevity are mediated by autophagy

Tavernarakis, N., Pasparaki, A., Tasdemir, E., Maiuri, M. C., & Kroemer, G. (2008) · Autophagy

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 132

The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer

Ladoire, S., Enot, D., Senovilla, L., Ghiringhelli, F., Poirier-Colame, V., Chaba, K., Semeraro, M., Chaix, M., Penault-Llorca, F., Arnould, L., et al. (2016) · Autophagy

Cancer Immunotherapy and BiomarkersAutophagy in Disease and Therapy

Cited by 117

Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis

Yonekura, S., Terrisse, S., Alves Costa Silva, C., Lafarge, A., Iebba, V., Ferrere, G., Goubet, A.-G., Fahrner, J.-E., Lahmar, I., Ueda, K., et al. (2022) · Cancer Discovery

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 112

Non‐apoptotic functions of apoptosis‐regulatory proteins

Galluzzi, L., Kepp, O., Trojel‐Hansen, C., & Kroemer, G. (2012) · The EMBO Reports

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 109

Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens

Fernández, Á. F., Bárcena, C., Martínez-García, G. G., Tamargo-Gómez, I., Suárez, M. F., Pietrocola, F., Castoldi, F., Esteban, L., Sierra-Filardi, E., Boya, P., et al. (2017) · Cell Death & Disease

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 109

Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity

Abdellatif, M., Trummer-Herbst, V., Heberle, A. M., Humnig, A., Pendl, T., Durand, S., Cerrato, G., Hofer, S. J., Islam, M., Voglhuber, J., et al. (2022) · Circulation

Genetics, Aging, and Longevity in Model OrganismsGrowth Hormone and Insulin-like Growth Factors

Cited by 108

Trial Watch: experimental TLR7/TLR8 agonists for oncological indications

Frega, G., Wu, Q., Le Naour, J., Vacchelli, E., Galluzzi, L., Kroemer, G., & Kepp, O. (2020) · OncoImmunology

Immunotherapy and Immune ResponsesImmune Response and Inflammation

Cited by 108

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis

Nassif, M., Valenzuela, V., Rojas-Rivera, D., Vidal, R., Matus, S., Castillo, K., Fuentealba, Y., Kroemer, G., Levine, B., & Hetz, C. (2014) · Autophagy

Amyotrophic Lateral Sclerosis ResearchAutophagy in Disease and Therapy

Cited by 100

A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR

Tosco, A., De Gregorio, F., Esposito, S., De Stefano, D., Sana, I., Ferrari, E., Sepe, A., Salvadori, L., Buonpensiero, P., Di Pasqua, A., et al. (2016) · Cell Death & Differentiation

Cystic Fibrosis Research AdvancesGenetic and Kidney Cyst Diseases

Cited by 92

Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina

Notomi, S., Ishihara, K., Efstathiou, N. E., Lee, J.-J., Hisatomi, T., Tachibana, T., Konstantinou, E. K., Ueta, T., Murakami, Y., Maidana, D. E., et al. (2019) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsAutophagy in Disease and Therapy

Cited by 92

Organs on chip approach: a tool to evaluate cancer -immune cells interactions

Biselli, E., Agliari, E., Barra, A., Bertani, F. R., Gerardino, A., De Ninno, A., Mencattini, A., Di Giuseppe, D., Mattei, F., Schiavoni, G., et al. (2017) · Scientific Reports

Mathematical Biology Tumor Growth3D Printing in Biomedical Research

Cited by 91