Eschalier, Alain
Inserm · Université Clermont Auvergne · Physiopathologie et pharmacologie de la douleur et de la migraine
29 papers on CoChatORCID 0000-0001-6778-1057
Most cited papers
- Verified
Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic pain
Courteix, C., Eschalier, A., & Lavarenne, J. (1993) · Pain
Pain Mechanisms and TreatmentsPain Management and Treatment
Cited by 454
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Analgesic effect of acetaminophen in humans: First evidence of a central serotonergic mechanism
PICKERING, G., LORIOT, M., LIBERT, F., ESCHALIER, A., BEAUNE, P., & DUBRAY, C. (2006) · Clinical Pharmacology & Therapeutics
Pain Mechanisms and TreatmentsPain Management and Opioid Use
Cited by 283
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Endocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesia
Mallet, C., Daulhac, L., Bonnefont, J., Ledent, C., Etienne, M., Chapuy, E., Libert, F., & Eschalier, A. (2008) · Pain
Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments
Cited by 223
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Rectal instillation of butyrate provides a novel clinically relevant model of noninflammatory colonic hypersensitivity in rats
Bourdu, S., Dapoigny, M., Chapuy, E., Artigue, F., Vasson, M.-P., Dechelotte, P., Bommelaer, G., Eschalier, A., & Ardid, D. (2005) · Gastroenterology
Gastrointestinal motility and disordersPain Mechanisms and Treatments
Cited by 176
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Description of a short-term Taxol®-induced nociceptive neuropathy in rats
Authier, N., Gillet, J.-P., Fialip, J., Eschalier, A., & Coudore, F. (2000) · Brain Research
Cancer Treatment and PharmacologyPain Mechanisms and Treatments
Cited by 171
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Acetaminophen Reinforces Descending Inhibitory Pain Pathways
Pickering, G., Estève, V, Loriot, M.-A., Eschalier, A., & Dubray, C. (2008) · Clinical Pharmacology & Therapeutics
Pain Mechanisms and TreatmentsPain Management and Opioid Use
Cited by 168
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TRPV1 in Brain Is Involved in Acetaminophen-Induced Antinociception
Mallet, C., Barrière, D. A., Ermund, A., Jönsson, B. A. G., Eschalier, A., Zygmunt, P. M., & Högestätt, E. D. (2010) · PLoS ONE
Pain Mechanisms and TreatmentsIon Channels and Receptors
Cited by 165
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T-Type Calcium Channel Inhibition Underlies the Analgesic Effects of the Endogenous Lipoamino Acids
Barbara, G., Alloui, A., Nargeot, J., Lory, P., Eschalier, A., Bourinet, E., & Chemin, J. (2009) · The Journal of Neuroscience
Ion Channels and ReceptorsPain Mechanisms and Treatments
Cited by 125
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Paracetamol exerts a spinal antinociceptive effect involving an indirect interaction with 5-hydroxytryptamine3 receptors: in vivo and in vitro evidence.
Pelissier, T., Alloui, A., Caussade, F., Dubray, C., Cloarec, A., Lavarenne, J., & Eschalier, A. (1996) · The Journal of Pharmacology and Experimental Therapeutics
Pain Mechanisms and TreatmentsAnesthesia and Pain Management
Cited by 107
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Anti-nociceptive effect of Faecalibacterium prausnitzii in non-inflammatory IBS-like models
Miquel, S., Martín, R., Lashermes, A., Gillet, M., Meleine, M., Gelot, A., Eschalier, A., Ardid, D., Bermúdez-Humarán, L. G., Sokol, H., et al. (2016) · Scientific Reports
Gastrointestinal motility and disordersGut microbiota and health
Cited by 105
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An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact
Mallet, C., Desmeules, J., Pegahi, R., & Eschalier, A. (2023) · Journal of Pain Research
Pain Mechanisms and TreatmentsCannabis and Cannabinoid Research
Cited by 83
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Paracetamol exerts a spinal, tropisetron-reversible, antinociceptive effect in an inflammatory pain model in rats
Alloui, A., Chassaing, C., Schmidt, J., Ardid, D., Dubray, C., Cloarec, A., & Eschalier, A. (2002) · European Journal of Pharmacology
Pain Mechanisms and TreatmentsAnesthesia and Pain Management
Cited by 83
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Spinal 5-HT1A receptors differentially influence nociceptive processing according to the nature of the noxious stimulus in rats: effect of WAY-100635 on the antinociceptive activities of paracetamol, venlafaxine and 5-HT
Bonnefont, J., Chapuy, E., Clottes, E., Alloui, A., & Eschalier, A. (2005) · Pain
Pain Mechanisms and TreatmentsNeurotransmitter Receptor Influence on Behavior
Cited by 81
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Benzodiazepine dependence: Focus on withdrawal syndrome
Authier, N., Balayssac, D., Sautereau, M., Zangarelli, A., Courty, P., Somogyi, A. A., Vennat, B., Llorca, P.-M., & Eschalier, A. (2009) · Annales Pharmaceutiques Françaises
Substance Abuse Treatment and OutcomesPharmaceutical Practices and Patient Outcomes
Cited by 79
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Effects of acetaminophen on monoaminergic systems in the rat central nervous system
Courade, J.-P., Caussade, F., Martin, K., Besse, D., Delchambre, C., Hanoun, N., Hamon, M., Eschalier, A., & Cloarec, A. (2001) · Naunyn-Schmiedeberg's Archives of Pharmacology
Pain Mechanisms and TreatmentsNeurotransmitter Receptor Influence on Behavior
Cited by 79
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Pain related behaviour during vincristine-induced neuropathy in rats
Authier, N., Coudore, F., Eschalier, A., & Fialip, J. (1999) · NeuroReport
Pain Mechanisms and TreatmentsCancer Treatment and Pharmacology
Cited by 77
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Orally Administered Paracetamol Does Not Act Locally in the Rat Formalin Test: Evidence for a Supraspinal, Serotonin-dependent Antinociceptive Mechanism
Bonnefont, J., Alloui, A., Chapuy, E., Clottes, E., & Eschalier, A. (2003) · Anesthesiology
Pain Mechanisms and TreatmentsInflammatory mediators and NSAID effects
Cited by 74
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Cav3.2 calcium channels: The key protagonist in the supraspinal effect of paracetamol
Kerckhove, N., Mallet, C., François, A., Boudes, M., Chemin, J., Voets, T., Bourinet, E., Alloui, A., & Eschalier, A. (2014) · Pain
Ion Channels and ReceptorsPain Mechanisms and Treatments
Cited by 65
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Fatty Acid Amide Hydrolase-Dependent Generation of Antinociceptive Drug Metabolites Acting on TRPV1 in the Brain
Barrière, D. A., Mallet, C., Blomgren, A., Simonsen, C., Daulhac, L., Libert, F., Chapuy, E., Etienne, M., Högestätt, E. D., Zygmunt, P. M., et al. (2013) · PLoS ONE
Pain Mechanisms and TreatmentsCannabis and Cannabinoid Research
Cited by 62
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Benzodiazepine Withdrawal Seizures: Analysis of 48 Case Reports
Fialip, J., Aumaitre, O., Eschalier, A., Maradeix, B., Dordain, G., & Lavarenne, J. (1987) · Clinical Neuropharmacology
Epilepsy research and treatmentPharmacovigilance and Adverse Drug Reactions
Cited by 53
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Acetaminophen Recruits Spinal p42/p44 MAPKs and GH/IGF-1 Receptors to Produce Analgesia via the Serotonergic System
Bonnefont, J., Daulhac, L., Etienne, M., Chapuy, E., Mallet, C., Ouchchane, L., Deval, C., Courade, J.-P., Ferrara, M., Eschalier, A., et al. (2007) · Molecular Pharmacology
Pain Mechanisms and TreatmentsNeuroscience and Neuropharmacology Research
Cited by 39
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Tropisetron inhibits the antinociceptive effect of intrathecally administered paracetamol and serotonin
Alloui, A., Pelissier, T., Dubray, C., Lavarenne, J., & Eschalier, A. (1996) · Fundamental & Clinical Pharmacology
Pain Mechanisms and TreatmentsPain Management and Opioid Use
Cited by 36
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Paracetamol is a centrally acting analgesic using mechanisms located in the periaqueductal grey
Barrière, D. A., Boumezbeur, F., Dalmann, R., Cadeddu, R., Richard, D., Pinguet, J., Daulhac, L., Sarret, P., Whittingstall, K., Keller, M., et al. (2020) · British Journal of Pharmacology
Pain Mechanisms and TreatmentsCannabis and Cannabinoid Research
Cited by 34
- Verified
Supra-spinal FAAH is required for the analgesic action of paracetamol in an inflammatory context
Dalmann, R., Daulhac, L., Antri, M., Eschalier, A., & Mallet, C. (2015) · Neuropharmacology
Pain Mechanisms and TreatmentsCannabis and Cannabinoid Research
Cited by 32
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