Morrison, Sean J.

Stem cells, cancer, and cancer stem cells

Reya, T., Morrison, S. J., Clarke, M. F., & Weissman, I. L. (2001) · Nature

Cancer Cells and MetastasisDevelopmental Biology and Gene Regulation

Cited by 9,738

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

Kiel, M. J., Yilmaz, Ö. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005) · Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 3,168

The bone marrow niche for haematopoietic stem cells

Morrison, S. J., & Scadden, D. T. (2014) · Nature

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 2,451

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells.

Park, I.-K., Qian, D., Kiel, M., Becker, M. W., Pihalja, M., Weissman, I. L., Morrison, S. J., & Clarke, M. F. (2003) · Nature

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 1,871

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

Zhou, B. O., Yue, R., Murphy, M. M., Peyer, J. G., & Morrison, S. J. (2014) · Cell Stem Cell

Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation

Cited by 1,381

Oxidative stress inhibits distant metastasis by human melanoma cells

Piskounova, E., Agathocleous, M., Murphy, M. M., Hu, Z., Huddlestun, S. E., Zhao, Z., Leitch, A. M., Johnson, T. M., DeBerardinis, R. J., & Morrison, S. J. (2015) · Nature

Cancer Cells and MetastasisRedox biology and oxidative stress

Cited by 1,269

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

Molofsky, A. V., Slutsky, S. G., Joseph, N. M., He, S., Pardal, R., Krishnamurthy, J., Sharpless, N. E., & Morrison, S. J. (2006) · Nature

Neurogenesis and neuroplasticity mechanismsTelomeres, Telomerase, and Senescence

Cited by 972

In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

Cheshier, S. H., Morrison, S. J., Liao, X., & Weissman, I. L. (1999) · Proceedings of the National Academy of Sciences

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 858

Adult haematopoietic stem cell niches

Crane, G. M., Jeffery, E., & Morrison, S. J. (2017) · Nature Reviews Immunology

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 712

Haematopoietic stem cells require a highly regulated protein synthesis rate

Signer, R. A. J., Magee, J. A., Salic, A., & Morrison, S. J. (2014) · Nature

Hematopoietic Stem Cell TransplantationRNA and protein synthesis mechanisms

Cited by 674

The purification and characterization of fetal liver hematopoietic stem cells

Morrison, S. J., Hemmati, H. D., Wandycz, A. M., & Weissman, I. L. (1995) · Proceedings of the National Academy of Sciences

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 611

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

Agathocleous, M., Meacham, C. E., Burgess, R. J., Piskounova, E., Zhao, Z., Crane, G. M., Cowin, B. L., Bruner, E., Murphy, M. M., Chen, W., et al. (2017) · Nature

Hematopoietic Stem Cell TransplantationVitamin C and Antioxidants Research

Cited by 545

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

Nakada, D., Saunders, T. L., & Morrison, S. J. (2010) · Nature

Hematopoietic Stem Cell TransplantationMetabolism, Diabetes, and Cancer

Cited by 524

Metabolic heterogeneity confers differences in melanoma metastatic potential

Tasdogan, A., Faubert, B., Ramesh, V., Ubellacker, J. M., Shen, B., Solmonson, A., Murphy, M. M., Gu, Z., Gu, W., Martin, M., et al. (2020) · Nature

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 509

Bmi1, stem cells, and senescence regulation

Park, I.-K., Morrison, S. J., & Clarke, M. F. (2004) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceHematopoietic Stem Cell Transplantation

Cited by 495

Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU

Kiel, M. J., He, S., Ashkenazi, R., Gentry, S. N., Teta, M., Kushner, J. A., Jackson, T. L., & Morrison, S. J. (2007) · Nature

Hematopoietic Stem Cell TransplantationTelomeres, Telomerase, and Senescence

Cited by 417

Telomerase Activity in Hematopoietic Cells Is Associated with Self-Renewal Potential

Morrison, S. J., Prowse, K. R., Ho, P., & Weissman, I. L. (1996) · Immunity

Telomeres, Telomerase, and SenescenceHematopoietic Stem Cell Transplantation

Cited by 394

Mechanisms that Regulate Stem Cell Aging and Life Span

Signer, R. A. J., & Morrison, S. J. (2013) · Cell Stem Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 320

A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis

Shen, B., Tasdogan, A., Ubellacker, J. M., Zhang, J., Nosyreva, E. D., Du, L., Murphy, M. M., Hu, S., Yi, Y., Kara, N., et al. (2021) · Nature

Bone Metabolism and DiseasesHematopoietic Stem Cell Transplantation

Cited by 310

De novo and salvage purine synthesis pathways across tissues and tumors

Tran, D. H., Kim, D., Kesavan, R., Brown, H., Dey, T., Soflaee, M. H., Vu, H. S., Tasdogan, A., Guo, J., Bezwada, D., et al. (2024) · Cell

Biochemical and Molecular ResearchAdenosine and Purinergic Signaling

Cited by 213

Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation

Gu, Z., Liu, Y., Cai, F., Patrick, M., Zmajkovic, J., Cao, H., Zhang, Y., Tasdogan, A., Chen, M., Qi, L., et al. (2019) · Cancer Discovery

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 173

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

Signer, R. A. J., Qi, L., Zhao, Z., Thompson, D., Sigova, A. A., Fan, Z. P., DeMartino, G. N., Young, R. A., Sonenberg, N., & Morrison, S. J. (2016) · Genes & Development

Hematopoietic Stem Cell TransplantationRNA and protein synthesis mechanisms

Cited by 115

Metabolic regulation of somatic stem cells in vivo

Meacham, C. E., DeVilbiss, A. W., & Morrison, S. J. (2022) · Nature Reviews Molecular Cell Biology

Metabolism, Diabetes, and CancerMesenchymal stem cell research

Cited by 85