Lehtimäki, Terho

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyGenetics, Aging, and Longevity in Model Organisms

Cited by 161

Cerebral MRI abnormalities and their association with neuropsychiatric manifestations in SLE: a population‐based study

Ainiala, H., Dastidar, P., Loukkola, J., Lehtimäki, T., Korpela, M., Peltola, J., & Hietaharju, A. (2005) · Scandinavian Journal of Rheumatology

Systemic Lupus Erythematosus ResearchDementia and Cognitive Impairment Research

Cited by 149

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

Wild, P. S., Felix, J. F., Schillert, A., Teumer, A., Chen, M.-H., Leening, M. J. G., Völker, U., Großmann, V., Brody, J. A., Irvin, M. R., et al. (2017) · Journal of Clinical Investigation

Genetic Associations and EpidemiologyCardiac electrophysiology and arrhythmias

Cited by 129

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses

Aho, V., Ollila, H. M., Kronholm, E., Bondia-Pons, I., Soininen, P., Kangas, A. J., Hilvo, M., Seppälä, I., Kettunen, J., Oikonen, M., et al. (2016) · Scientific Reports

Sleep and Work-Related FatigueCircadian rhythm and melatonin

Cited by 126

Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence

Wang, Q., Würtz, P., Auro, K., Morin-Papunen, L., Kangas, A. J., Soininen, P., Tiainen, M., Tynkkynen, T., Joensuu, A., Havulinna, A. S., et al. (2016) · International Journal of Epidemiology

Reproductive Health and ContraceptionMetabolomics and Mass Spectrometry Studies

Cited by 117

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Cade, B. E., Gottlieb, D. J., Hruby, A., Jacques, P. F., Lamon-Fava, S., Richardson, K., et al. (2015) · The American Journal of Clinical Nutrition

Sleep and related disordersCircadian rhythm and melatonin

Cited by 112

Decreased skeletal muscle mitochondrial DNA in patients treated with high-dose simvastatin

Schick, B. A., Laaksonen, R., Frohlich, J. J., Päivä, H., Lehtimäki, T., Humphries, K. H., & Côté, H. C. F. (2007) · Clinical Pharmacology & Therapeutics

Mitochondrial Function and PathologyLipoproteins and Cardiovascular Health

Cited by 103

Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

NCD Risk Factor Collaboration (NCD-RisC), Zhou, B., Sheffer, K. E., Bennett, J. E., Gregg, E. W., Danaei, G., Singleton, R. K., Shaw, J. E., Mishra, A., Lhoste, V. P. F., et al. (2023) · Nature Medicine

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and Research

Cited by 94

Meta-Analysis Investigating Associations Between Healthy Diet and Fasting Glucose and Insulin Levels and Modification by Loci Associated With Glucose Homeostasis in Data From 15 Cohorts

Nettleton, J. A., Hivert, M.-F., Lemaitre, R. N., McKeown, N. M., Mozaffarian, D., Tanaka, T., Wojczynski, M. K., Hruby, A., Djoussé, L., Ngwa, J. S., et al. (2013) · American Journal of Epidemiology

Nutrition, Genetics, and DiseaseNutritional Studies and Diet

Cited by 89

Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis

Wang, Q., Oliver-Williams, C., Raitakari, O. T., Viikari, J., Lehtimäki, T., Kähönen, M., Järvelin, M.-R., Salomaa, V., Perola, M., Danesh, J., et al. (2021) · European Heart Journal

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 89

Distinct Variants at LIN28B Influence Growth in Height from Birth to Adulthood

Widén, E., Ripatti, S., Cousminer, D. L., Surakka, I., Lappalainen, T., Järvelin, M.-R., Eriksson, J. G., Raitakari, O., Salomaa, V., Sovio, U., et al. (2010) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyHypothalamic control of reproductive hormones

Cited by 88

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L., Schwantes-An, T.-H., Coon, H., Han, Y., Stephens, S. H., Sun, J., et al. (2012) · Archives of General Psychiatry

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 75

Genetic association study of childhood aggression across raters, instruments, and age

Ip, H. F., van der Laan, C. M., Krapohl, E. M. L., Brikell, I., Sánchez-Mora, C., Nolte, I. M., St Pourcain, B., Bolhuis, K., Palviainen, T., Zafarmand, H., et al. (2021) · Translational Psychiatry

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 71

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case–control cohort

Elias-Sonnenschein, L. S., Helisalmi, S., Natunen, T., Hall, A., Paajanen, T., Herukka, S.-K., Laitinen, M., Remes, A. M., Koivisto, A. M., Mattila, K. M., et al. (2013) · PLoS ONE

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 70

Diminishing benefits of urban living for children and adolescents' growth and development

NCD Risk Factor Collaboration (NCD-RisC), Mishra, A., Zhou, B., Rodriguez-Martinez, A., Bixby, H., Singleton, R. K., Carrillo-Larco, R. M., Sheffer, K. E., Paciorek, C. J., Bennett, J. E., et al. (2023) · Nature

Obesity, Physical Activity, DietHuman Health and Disease

Cited by 70

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

Merino, J., Dashti, H. S., Li, S. X., Sarnowski, C., Justice, A. E., Graff, M., Papoutsakis, C., Smith, C. E., Dedoussis, G. V., Lemaitre, R. N., et al. (2019) · Molecular Psychiatry

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 66

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S.-J., Isaacs, A., et al. (2016) · Circulation: Cardiovascular Genetics

Genetic Associations and EpidemiologyAtherosclerosis and Cardiovascular Diseases

Cited by 66

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

Sliz, E., Kalaoja, M., Ahola-Olli, A., Raitakari, O., Perola, M., Salomaa, V., Lehtimäki, T., Karhu, T., Viinamäki, H., Salmi, M., et al. (2019) · Journal of Medical Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 60

The effect of apolipoprotein E polymorphism on serum metabolome – a population-based 10-year follow-up study

Karjalainen, J.-P., Mononen, N., Hutri-Kähönen, N., Lehtimäki, M., Juonala, M., Ala-Korpela, M., Kähönen, M., Raitakari, O., & Lehtimäki, T. (2019) · Scientific Reports

Lipoproteins and Cardiovascular HealthMetabolomics and Mass Spectrometry Studies

Cited by 55

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

Polfus, L. M., Khajuria, R. K., Schick, U. M., Pankratz, N., Pazoki, R., Brody, J. A., Chen, M.-H., Auer, P. L., Floyd, J. S., Huang, J., et al. (2016) · The American Journal of Human Genetics

Platelet Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 54

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J.-W., et al. (2022) · Nature Communications

Cardiac electrophysiology and arrhythmiasGenetic Associations and Epidemiology

Cited by 49

Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

Lim, E. T., Würtz, P., Havulinna, A. S., Palta, P., Tukiainen, T., Rehnström, K., Esko, T., Mägi, R., Inouye, M., Lappalainen, T., et al. (2014) · PLoS Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 49

Serotonin receptor 1B genotype and hostility, anger and aggressive behavior through the lifespan: the Young Finns study

Hakulinen, C., Jokela, M., Hintsanen, M., Merjonen, P., Pulkki-Råback, L., Seppälä, I., Lyytikäinen, L.-P., Lehtimäki, T., Kähönen, M., Viikari, J., et al. (2013) · Journal of Behavioral Medicine

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 47

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

Kettunen, J., Holmes, M. V., Allara, E., Anufrieva, O., Ohukainen, P., Oliver-Williams, C., Wang, Q., Tillin, T., Hughes, A. D., Kähönen, M., et al. (2019) · PLOS Biology

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 47