Grune, Tilman

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Role of advanced glycation end products in cellular signaling

Ott, C., Jacobs, K., Haucke, E., Navarrete Santos, A., Grune, T., & Simm, A. (2014) · Redox Biology

Advanced Glycation End Products researchPotato Plant Research

Cited by 1,150

Advanced Glycation End Products and Oxidative Stress in Type 2 Diabetes Mellitus

Nowotny, K., Jung, T., Höhn, A., Weber, D., & Grune, T. (2015) · Biomolecules

Advanced Glycation End Products researchPotato Plant Research

Cited by 1,095

β-Carotene Is an Important Vitamin A Source for Humans

Grune, T., Lietz, G., Palou, A., Ross, A. C., Stahl, W., Tang, G., Thurnham, D., Yin, S.-A., & Biesalski, H. K. (2010) · The Journal of Nutrition

Antioxidant Activity and Oxidative StressRetinoids in leukemia and cellular processes

Cited by 587

Proteasome inhibition by paired helical filament‐tau in brains of patients with Alzheimer's disease

Keck, S., Nitsch, R., Grune, T., & Ullrich, O. (2003) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsUbiquitin and proteasome pathways

Cited by 483

Comparative resistance of the 20S and 26S proteasome to oxidative stress

REINHECKEL, T., SITTE, N., ULLRICH, O., KUCKELKORN, U., DAVIES, K. J. A., & GRUNE, T. (1998) · Biochemical Journal

Ubiquitin and proteasome pathwaysRedox biology and oxidative stress

Cited by 447

Lipofuscin: Formation, Distribution, and Metabolic Consequences

JUNG, T., BADER, N., & GRUNE, T. (2007) · Annals of the New York Academy of Sciences

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 415

Lipofuscin: formation, effects and role of macroautophagy

Höhn, A., & Grune, T. (2013) · Redox Biology

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 298

Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

Weber, D., Davies, M. J., & Grune, T. (2015) · Redox Biology

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 295

Dietary advanced glycation end products and their relevance for human health

Nowotny, K., Schröter, D., Schreiner, M., & Grune, T. (2018) · Ageing Research Reviews

Advanced Glycation End Products researchPotato Plant Research

Cited by 255

Age-associated analysis of oxidative stress parameters in human plasma and erythrocytes

Gil, L., Siems, W., Mazurek, B., Gross, J., Schroeder, P., Voss, P., & Grune, T. (2006) · Free Radical Research

Antioxidant Activity and Oxidative StressRedox biology and oxidative stress

Cited by 242

Molecular effects of advanced glycation end products on cell signalling pathways, ageing and pathophysiology

Nedić, O., Rattan, S. I. S., Grune, T., & Trougakos, I. P. (2013) · Free Radical Research

Advanced Glycation End Products researchPotato Plant Research

Cited by 162

4-Hydroxynonenal-modified amyloid-β peptide inhibits the proteasome: possible importance in Alzheimer’s disease*

Shringarpure, R., Grune, T., Sitte, N., & Davies*, K. J. A. (2000) · Cellular and Molecular Life Sciences

Alzheimer's disease research and treatmentsUbiquitin and proteasome pathways

Cited by 140

Validation of protein carbonyl measurement: A multi-centre study

Augustyniak, E., Adam, A., Wojdyla, K., Rogowska-Wrzesinska, A., Willetts, R., Korkmaz, A., Atalay, M., Weber, D., Grune, T., Borsa, C., et al. (2015) · Redox Biology

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 135

Impaired proteostasis during skeletal muscle aging

Fernando, R., Drescher, C., Nowotny, K., Grune, T., & Castro, J. P. (2019) · Free Radical Biology and Medicine

Muscle Physiology and DisordersGenetics, Aging, and Longevity in Model Organisms

Cited by 134

Advanced glycation end products and protein carbonyl levels in plasma reveal sex-specific differences in Parkinson's and Alzheimer's disease

Sharma, A., Weber, D., Raupbach, J., Dakal, T. C., Fließbach, K., Ramirez, A., Grune, T., & Wüllner, U. (2020) · Redox Biology

Advanced Glycation End Products researchAlzheimer's disease research and treatments

Cited by 120

Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts

Ott, C., König, J., Höhn, A., Jung, T., & Grune, T. (2016) · Redox Biology

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 96

The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium

Gerhardt, C., Lier, J. M., Burmühl, S., Struchtrup, A., Deutschmann, K., Vetter, M., Leu, T., Reeg, S., Grune, T., & Rüther, U. (2015) · Journal of Cell Biology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 88

Advanced-glycation-end-product-induced formation of immunoproteasomes: involvement of RAGE and Jak2/STAT1

Grimm, S., Ott, C., Hörlacher, M., Weber, D., Höhn, A., & Grune, T. (2012) · Biochemical Journal

Advanced Glycation End Products researchUbiquitin and proteasome pathways

Cited by 87

Mitochondrial Chaperones in the Brain: Safeguarding Brain Health and Metabolism?

Castro, J. P., Wardelmann, K., Grune, T., & Kleinridders, A. (2018) · Frontiers in Endocrinology

Heat shock proteins researchMitochondrial Function and Pathology

Cited by 53

Rapid and sensitive determination of protein-nitrotyrosine by ELISA: Application to human plasma

Weber, D., Kneschke, N., Grimm, S., Bergheim, I., Breusing, N., & Grune, T. (2012) · Free Radical Research

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 47

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK‐AGE Project

Weber, D., Stuetz, W., Toussaint, O., Debacq-Chainiaux, F., Dollé, M. E. T., Jansen, E., Gonos, E. S., Franceschi, C., Sikora, E., Hervonen, A., et al. (2017) · Oxidative Medicine and Cellular Longevity

Antioxidant Activity and Oxidative StressGenetics, Aging, and Longevity in Model Organisms

Cited by 46

Age-related loss of stress-induced nuclear proteasome activation is due to low PARP-1 activity

Bakondi, E., Catalgol, B., Bak, I., Jung, T., Bozaykut, P., Bayramicli, M., Ozer, N. K., & Grune, T. (2011) · Free Radical Biology and Medicine

Ubiquitin and proteasome pathwaysGenetics, Aging, and Longevity in Model Organisms

Cited by 30