Svoboda, Karel

Ultrasensitive fluorescent proteins for imaging neuronal activity

Chen, T.-W., Wardill, T. J., Sun, Y., Pulver, S. R., Renninger, S. L., Baohan, A., Schreiter, E. R., Kerr, R. A., Orger, M. B., Jayaraman, V., et al. (2013) · Nature

Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research

Cited by 6,474

Fully integrated silicon probes for high-density recording of neural activity

Jun, J. J., Steinmetz, N. A., Siegle, J. H., Denman, D. J., Bauza, M., Barbarits, B., Lee, A. K., Anastassiou, C. A., Andrei, A., Aydın, Ç., et al. (2017) · Nature

Neuroscience and Neural EngineeringAnalog and Mixed-Signal Circuit Design

Cited by 2,190

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

Tian, L., Hires, S. A., Mao, T., Huber, D., Chiappe, M. E., Chalasani, S. H., Petreanu, L., Akerboom, J., McKinney, S. A., Schreiter, E. R., et al. (2009) · Nature Methods

Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research

Cited by 1,967

Experience-dependent structural synaptic plasticity in the mammalian brain

Holtmaat, A., & Svoboda, K. (2009) · Nature Reviews Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 1,934

Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

Trachtenberg, J. T., Chen, B. E., Knott, G. W., Feng, G., Sanes, J. R., Welker, E., & Svoboda, K. (2002) · Nature

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 1,927

Direct observation of kinesin stepping by optical trapping interferometry

Svoboda, K., Schmidt, C. F., Schnapp, B. J., & Block, S. M. (1993) · Nature

Microtubule and mitosis dynamicsForce Microscopy Techniques and Applications

Cited by 1,910

Shared and distinct transcriptomic cell types across neocortical areas

Tasic, B., Yao, Z., Graybuck, L. T., Smith, K. A., Nguyen, T. N., Bertagnolli, D., Goldy, J., Garren, E., Economo, M. N., Viswanathan, S., et al. (2018) · Nature

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 1,746

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

Madisen, L., Mao, T., Koch, H., Zhuo, J.-M., Berenyi, A., Fujisawa, S., Hsu, Y.-W. A., Garcia, A. J., Gu, X., Zanella, S., et al. (2012) · Nature Neuroscience

Photoreceptor and optogenetics researchNeuroscience and Neuropharmacology Research

Cited by 1,398

Rapid Spine Delivery and Redistribution of AMPA Receptors After Synaptic NMDA Receptor Activation

Shi, S.-H., Hayashi, Y., Petralia, R. S., Zaman, S. H., Wenthold, R. J., Svoboda, K., & Malinow, R. (1999) · Science

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 1,276

Structure and function of dendritic spines

Nimchinsky, E. A., Sabatini, B. L., & Svoboda, K. (2002) · Annual Review of Physiology

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 1,208

Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings.

Steinmetz, N. A., Aydin, C., Lebedeva, A., Okun, M., Pachitariu, M., Bauza, M., Beau, M., Bhagat, J., Böhm, C., Broux, M., et al. (2021) · Science

Neuroscience and Neural EngineeringNeural dynamics and brain function

Cited by 1,173

Transient and persistent dendritic spines in the neocortex in vivo

Holtmaat, A. J. G. D., Trachtenberg, J. T., Wilbrecht, L., Shepherd, G. M., Zhang, X., Knott, G. W., & Svoboda, K. (2005) · Neuron

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 1,131

The subcellular organization of neocortical excitatory connections

Petreanu, L., Mao, T., Sternson, S. M., & Svoboda, K. (2009) · Nature

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 1,047

Principles of two-photon excitation microscopy and its applications to neuroscience

Svoboda, K., & Yasuda, R. (2006) · Neuron

Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research

Cited by 1,027

Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections

Petreanu, L., Huber, D., Sobczyk, A., & Svoboda, K. (2007) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchPhotoreceptor and optogenetics research

Cited by 930

Force and velocity measured for single kinesin molecules

Svoboda, K., & Block, S. M. (1994) · Cell

Microtubule and mitosis dynamicsForce Microscopy Techniques and Applications

Cited by 909

Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo

Lendvai, B., Stern, E. A., Chen, B., & Svoboda, K. (2000) · Nature

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 802

The Life Cycle of Ca2+ Ions in Dendritic Spines

Sabatini, B. L., Oertner, T. G., & Svoboda, K. (2002) · Neuron

Neuroscience and Neuropharmacology ResearchIon channel regulation and function

Cited by 745

Cortical rewiring and information storage

Chklovskii, D. B., Mel, B. W., & Svoboda, K. (2004) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 717

Flow of cortical activity underlying a tactile decision in mice

Guo, Z. V., Li, N., Huber, D., Ophir, E., Gutnisky, D., Ting, J. T., Feng, G., & Svoboda, K. (2014) · Neuron

Neural dynamics and brain functionMotor Control and Adaptation

Cited by 715

Experience-dependent and cell-type-specific spine growth in the neocortex

Holtmaat, A., Wilbrecht, L., Knott, G. W., Welker, E., & Svoboda, K. (2006) · Nature

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 631

Locally dynamic synaptic learning rules in pyramidal neuron dendrites

Harvey, C. D., & Svoboda, K. (2007) · Nature

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 625

Thy1-GCaMP6 transgenic mice for neuronal population imaging in vivo

Dana, H., Chen, T.-W., Hu, A., Shields, B. C., Guo, C., Looger, L. L., Kim, D. S., & Svoboda, K. (2014) · PLoS ONE

Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research

Cited by 574

Spine growth precedes synapse formation in the adult neocortex in vivo

Knott, G. W., Holtmaat, A., Wilbrecht, L., Welker, E., & Svoboda, K. (2006) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 563