Comabella, Manuel

Neurofilaments as biomarkers in neurological disorders

Khalil, M., Teunissen, C. E., Otto, M., Piehl, F., Sormani, M. P., Gattringer, T., Barro, C., Kappos, L., Comabella, M., Fazekas, F., et al. (2018) · Nature Reviews Neurology

Multiple Sclerosis Research StudiesHereditary Neurological Disorders

Cited by 1,988

A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking

Teunissen, C. E., Petzold, A., Bennett, J. L., Berven, F. S., Brundin, L., Comabella, M., Franciotta, D., Frederiksen, J. L., Fleming, J. O., Furlan, R., et al. (2009) · Neurology

Clinical Laboratory Practices and Quality ControlMultiple Sclerosis Research Studies

Cited by 845

Defining high, medium, and low impact prognostic factors for developing multiple sclerosis

Tintore, M., Rovira, À., Río, J., Otero-Romero, S., Arrambide, G., Tur, C., Comabella, M., Nos, C., Arévalo, M. J., Negrotto, L., et al. (2015) · Brain

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 530

Do oligoclonal bands add information to MRI in first attacks of multiple sclerosis?

Tintoré, M., Rovira, A., Río, J., Tur, C., Pelayo, R., Nos, C., Téllez, N., Perkal, H., Comabella, M., Sastre-Garriga, J., et al. (2008) · Neurology

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 345

Conversion from clinically isolated syndrome to multiple sclerosis: a large multicentre study

Kuhle, J., Disanto, G., Dobson, R., Adiutori, R., Bianchi, L., Topping, J., Bestwick, J., Meier, U.-C., Marta, M., Costa, G. D., et al. (2015) · Multiple Sclerosis Journal

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 299

Locus for severity implicates CNS resilience in progression of multiple sclerosis

International Multiple Sclerosis Genetics Consortium, Harroud, A., Stridh, P., McCauley, J. L., Saarela, J., van den Bosch, A. M. R., Engelenburg, H. J., Beecham, A. H., Alfredsson, L., Alikhani, K., et al. (2023) · Nature

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 243

Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes

Cantó, E., Tintoré, M., Villar, L. M., Costa, C., Nurtdinov, R., Álvarez-Cermeño, J. C., Arrambide, G., Reverter, F., Deisenhammer, F., Hegen, H., et al. (2015) · Brain

Multiple Sclerosis Research StudiesPeripheral Neuropathies and Disorders

Cited by 193

Identification of a Novel Risk Locus for Multiple Sclerosis at 13q31.3 by a Pooled Genome-Wide Scan of 500,000 Single Nucleotide Polymorphisms

Comabella, M., Craig, D. W., Camiña-Tato, M., Morcillo, C., Lopez, C., Navarro, A., Rio, J., BiomarkerMS Study Group, Montalban, X., & Martin, R. (2008) · PLoS ONE

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 105

Neurofilament ELISA validation

Petzold, A., Altintas, A., Andreoni, L., Bartos, A., Berthele, A., Blankenstein, M. A., Buee, L., Castellazzi, M., Cepok, S., Comabella, M., et al. (2010) · Journal of Immunological Methods

Clinical Laboratory Practices and Quality ControlReliability and Agreement in Measurement

Cited by 105

Effect of changes in MS diagnostic criteria over 25 years on time to treatment and prognosis in patients with clinically isolated syndrome

Tintore, M., Cobo-Calvo, A., Carbonell, P., Arrambide, G., Otero-Romero, S., Río, J., Tur, C., Comabella, M., Nos, C., Arévalo, M. J., et al. (2021) · Neurology

Multiple Sclerosis Research StudiesClinical Reasoning and Diagnostic Skills

Cited by 90

Chitinases and chitinase-like proteins as biomarkers in neurologic disorders

Pinteac, R., Montalban, X., & Comabella, M. (2021) · Neurology Neuroimmunology & Neuroinflammation

Studies on Chitinases and ChitosanasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 87

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis

Alcina, A., Fedetz, M., Fernández, Ó., Saiz, A., Izquierdo, G., Lucas, M., Leyva, L., García-León, J.-A., Abad-Grau, M. D. M., Alloza, I., et al. (2013) · Journal of Medical Genetics

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 69

Association of very early treatment initiation with the risk of long-term disability in patients with a first demyelinating event

Cobo-Calvo, A., Tur, C., Otero-Romero, S., Carbonell-Mirabent, P., Ruiz, M., Pappolla, A., Villacieros Alvarez, J., Vidal-Jordana, A., Arrambide, G., Castilló, J., et al. (2023) · Neurology

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 65

Contribution of the symptomatic lesion in establishing MS diagnosis and prognosis

Tintore, M., Otero-Romero, S., Río, J., Arrambide, G., Pujal, B., Tur, C., Galán, I., Comabella, M., Nos, C., Arévalo, M. J., et al. (2016) · Neurology

Multiple Sclerosis Research StudiesClinical Reasoning and Diagnostic Skills

Cited by 54

Chitinase 3-like 1 is neurotoxic in primary cultured neurons

Matute-Blanch, C., Calvo-Barreiro, L., Carballo-Carbajal, I., Gonzalo, R., Sanchez, A., Vila, M., Montalban, X., & Comabella, M. (2020) · Scientific Reports

Studies on Chitinases and ChitosanasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 38

Lesion topographies in multiple sclerosis diagnosis: A reappraisal

Arrambide, G., Tintore, M., Auger, C., Río, J., Castilló, J., Vidal-Jordana, A., Galán, I., Nos, C., Comabella, M., Mitjana, R., et al. (2017) · Neurology

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 38

Plasma chitotriosidase activity in multiple sclerosis

Comabella, M., Domínguez, C., Rio, J., Martín-Gallán, P., Vilches, A., Vilarrasa, N., Espejo, C., & Montalban, X. (2009) · Clinical Immunology

Multiple Sclerosis Research StudiesLysosomal Storage Disorders Research

Cited by 34

Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CLBL genes

Varadé, J., Comabella, M., Ortiz, M. A., Arroyo, R., Fernández, O., Pinto-Medel, M. J., Fedetz, M., Izquierdo, G., Lucas, M., Gómez, C. L., et al. (2012) · Multiple Sclerosis Journal

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 28

Prognostic factors for multiple sclerosis symptoms in radiologically isolated syndrome

Fissolo, N., Schaedelin, S., Villar, L. M., Lünemann, J. D., Correale, J., Rejdak, K., Schwab, N., Vilaseca, A., Held, F., García-Merino, A., et al. (2025) · JAMA Neurology

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 27

Value of NMO-IgG determination at the time of presentation as CIS

Costa, C., Arrambide, G., Tintore, M., Castilló, J., Sastre-Garriga, J., Tur, C., Río, J., Saiz, A., Vidal-Jordana, A., Auger, C., et al. (2012) · Neurology

Multiple Sclerosis Research StudiesOcular Diseases and Behçet’s Syndrome

Cited by 17

Should we systematically test patients with clinically isolated syndrome for auto-antibodies?

Negrotto, L., Tur, C., Tintoré, M., Arrambide, G., Sastre-Garriga, J., Río, J., Comabella, M., Nos, C., Galán, I., Vidal-Jordana, A., et al. (2015) · Multiple Sclerosis Journal

Multiple Sclerosis Research StudiesSystemic Lupus Erythematosus Research

Cited by 11