Yamamoto, Masayuki

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

Ishigaki, K., Akiyama, M., Kanai, M., Takahashi, A., Kawakami, E., Sugishita, H., Sakaue, S., Matoba, N., Low, S.-K., Okada, Y., et al. (2020) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 508

Keap1 degradation by autophagy for the maintenance of redox homeostasis

Taguchi, K., Fujikawa, N., Komatsu, M., Ishii, T., Unno, M., Akaike, T., Motohashi, H., & Yamamoto, M. (2012) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressAutophagy in Disease and Therapy

Cited by 482

Two-site substrate recognition model for the Keap1-Nrf2 system: A hinge and latch mechanism

Tong, K. I., Kobayashi, A., Katsuoka, F., & Yamamoto, M. (2006) · Biological Chemistry

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 473

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice

CHANAS, S. A., JIANG, Q., McMAHON, M., McWALTER, G. K., McLELLAN, L. I., ELCOMBE, C. R., HENDERSON, C. J., WOLF, C. R., MOFFAT, G. J., ITOH, K., et al. (2002) · Biochemical Journal

Genomics, phytochemicals, and oxidative stressGlutathione Transferases and Polymorphisms

Cited by 460

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population

Akiyama, M., Okada, Y., Kanai, M., Takahashi, A., Momozawa, Y., Ikeda, M., Iwata, N., Ikegawa, S., Hirata, M., Matsuda, K., et al. (2017) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 455

Transcription Factor Nrf2 Regulates Inflammation by Mediating the Effect of 15-Deoxy-Δ12,14-Prostaglandin J2

Itoh, K., Mochizuki, M., Ishii, Y., Ishii, T., Shibata, T., Kawamoto, Y., Kelly, V., Sekizawa, K., Uchida, K., & Yamamoto, M. (2004) · Molecular and Cellular Biology

Genomics, phytochemicals, and oxidative stressHeme Oxygenase-1 and Carbon Monoxide

Cited by 407

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

Sussan, T. E., Rangasamy, T., Blake, D. J., Malhotra, D., El-Haddad, H., Bedja, D., Yates, M. S., Kombairaju, P., Yamamoto, M., Liby, K. T., et al. (2009) · Proceedings of the National Academy of Sciences

Chronic Obstructive Pulmonary Disease (COPD) ResearchGenomics, phytochemicals, and oxidative stress

Cited by 346

Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes

Ohtsuji, M., Katsuoka, F., Kobayashi, A., Aburatani, H., Hayes, J. D., & Yamamoto, M. (2008) · Journal of Biological Chemistry

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 317

FANTOM5 CAGE profiles of human and mouse samples

Noguchi, S., Arakawa, T., Fukuda, S., Furuno, M., Hasegawa, A., Hori, F., Ishikawa-Kato, S., Kaida, K., Kaiho, A., Kanamori-Katayama, M., et al. (2017) · Scientific Data

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 310

Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis

Freigang, S., Ampenberger, F., Spohn, G., Heer, S., Shamshiev, A. T., Kisielow, J., Hersberger, M., Yamamoto, M., Bachmann, M. F., & Kopf, M. (2011) · European Journal of Immunology

Atherosclerosis and Cardiovascular DiseasesInflammasome and immune disorders

Cited by 300

Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust

Aoki, Y., Sato, H., Nishimura, N., Takahashi, S., Itoh, K., & Yamamoto, M. (2001) · Toxicology and Applied Pharmacology

Carcinogens and Genotoxicity AssessmentGenomics, phytochemicals, and oxidative stress

Cited by 297

Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response

Saito, R., Suzuki, T., Hiramoto, K., Asami, S., Naganuma, E., Suda, H., Iso, T., Yamamoto, H., Morita, M., Baird, L., et al. (2016) · Molecular and Cellular Biology

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 294

The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin

Hidaka, T., Ogawa, E., Kobayashi, E. H., Suzuki, T., Funayama, R., Nagashima, T., Fujimura, T., Aiba, S., Nakayama, K., Okuyama, R., et al. (2017) · Nature Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 274

Intrinsic Function of the Aryl Hydrocarbon (Dioxin) Receptor as a Key Factor in Female Reproduction

Baba, T., Mimura, J., Nakamura, N., Harada, N., Yamamoto, M., Morohashi, K.-I., & Fujii-Kuriyama, Y. (2005) · Molecular and Cellular Biology

Estrogen and related hormone effectsToxic Organic Pollutants Impact

Cited by 256

Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema

Ishii, Y., Itoh, K., Morishima, Y., Kimura, T., Kiwamoto, T., IIzuka, T., Hegab, A. E., Hosoya, T., Nomura, A., Sakamoto, T., et al. (2005) · The Journal of Immunology

Genomics, phytochemicals, and oxidative stressChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 248

The Keap1-Nrf2 system and diabetes mellitus

Uruno, A., Yagishita, Y., & Yamamoto, M. (2015) · Archives of Biochemistry and Biophysics

Genomics, phytochemicals, and oxidative stressEndoplasmic Reticulum Stress and Disease

Cited by 231

NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer

Shibata, T., Kokubu, A., Saito, S., Narisawa-Saito, M., Sasaki, H., Aoyagi, K., Yoshimatsu, Y., Tachimori, Y., Kushima, R., Kiyono, T., et al. (2011) · Neoplasia

Genomics, phytochemicals, and oxidative stressEsophageal Cancer Research and Treatment

Cited by 224

Essential and Instructive Roles of GATA Factors in Eosinophil Development

Hirasawa, R., Shimizu, R., Takahashi, S., Osawa, M., Takayanagi, S., Kato, Y., Onodera, M., Minegishi, N., Yamamoto, M., Fukao, K., et al. (2002) · The Journal of Experimental Medicine

Asthma and respiratory diseasesT-cell and B-cell Immunology

Cited by 219

BRG1 Interacts with Nrf2 To Selectively Mediate HO-1 Induction in Response to Oxidative Stress

Zhang, J., Ohta, T., Maruyama, A., Hosoya, T., Nishikawa, K., Maher, J. M., Shibahara, S., Itoh, K., & Yamamoto, M. (2006) · Molecular and Cellular Biology

Genomics, phytochemicals, and oxidative stressHeme Oxygenase-1 and Carbon Monoxide

Cited by 213

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism

Kansanen, E., Bonacci, G., Schopfer, F. J., Kuosmanen, S. M., Tong, K. I., Leinonen, H., Woodcock, S. R., Yamamoto, M., Carlberg, C., Ylä-Herttuala, S., et al. (2011) · Journal of Biological Chemistry

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 208

The KEAP1–NRF2 System as a Molecular Target of Cancer Treatment

Taguchi, K., & Yamamoto, M. (2020) · Cancers

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 195

Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions.

Tauchi, M., Hida, A., Negishi, T., Katsuoka, F., Noda, S., Mimura, J., Hosoya, T., Yanaka, A., Aburatani, H., Fujii-Kuriyama, Y., et al. (2005) · Molecular and Cellular Biology

Dermatology and Skin DiseasesToxic Organic Pollutants Impact

Cited by 167

Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse

Moriguchi, T., Motohashi, H., Hosoya, T., Nakajima, O., Takahashi, S., Ohsako, S., Aoki, Y., Nishimura, N., Tohyama, C., Fujii-Kuriyama, Y., et al. (2003) · Proceedings of the National Academy of Sciences

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 164

Expression of delta-aminolevulinate synthase in avian cells: Separate genes encode erythroid-specific and nonspecific isozymes

Riddle, R. D., Yamamoto, M., & Engel, J. D. (1989) · Proceedings of the National Academy of Sciences

Porphyrin Metabolism and DisordersHemoglobin structure and function

Cited by 163