Mignot, Emmanuel

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

Lin, L., Faraco, J., Li, R., Kadotani, H., Rogers, W., Lin, X., Qiu, X., de Jong, P. J., Nishino, S., & Mignot, E. (1999) · Cell

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 2,613

Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index

Taheri, S., Lin, L., Austin, D., Young, T., & Mignot, E. (2004) · PLoS Medicine

Regulation of Appetite and ObesitySleep and Wakefulness Research

Cited by 2,477

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Peyron, C., Faraco, J., Rogers, W., Ripley, B., Overeem, S., Charnay, Y., Nevsimalova, S., Aldrich, M., Reynolds, D., Albin, R., et al. (2000) · Nature Medicine

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 2,118

Hypocretin (orexin) deficiency in human narcolepsy

Nishino, S., Ripley, B., Overeem, S., Lammers, G. J., & Mignot, E. (2000) · The Lancet

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 1,776

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

Garrett-Bakelman, F. E., Darshi, M., Green, S. J., Gur, R. C., Lin, L., Macias, B. R., McKenna, M. J., Meydan, C., Mishra, T., Nasrini, J., et al. (2019) · Science

Spaceflight effects on biologySpace exploration and regulation

Cited by 1,128

The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias

Mignot, E., Lammers, G. J., Ripley, B., Okun, M., Nevsimalova, S., Overeem, S., Vankova, J., Black, J., Harsh, J., Bassetti, C., et al. (2002) · Archives of Neurology

Sleep and Wakefulness ResearchSleep and related disorders

Cited by 1,126

Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels

Ju, Y.-E. S., Ooms, S. J., Sutphen, C., Macauley, S. L., Zangrilli, M. A., Jerome, G., Fagan, A. M., Mignot, E., Zempel, J. M., Claassen, J. A. H. R., et al. (2017) · Brain

Sleep and Wakefulness ResearchAlzheimer's disease research and treatments

Cited by 604

Complex HLA-DR and -DQ Interactions Confer Risk of Narcolepsy-Cataplexy in Three Ethnic Groups

Mignot, E., Lin, L., Rogers, W., Honda, Y., Qiu, X., Lin, X., Okun, M., Hohjoh, H., Miki, T., Hsu, S. H., et al. (2001) · The American Journal of Human Genetics

Sleep and Wakefulness ResearchSleep and related disorders

Cited by 594

Effect of liraglutide 3.0 mg in individuals with obesity and moderate or severe obstructive sleep apnea: the SCALE Sleep Apnea randomized clinical trial

on behalf of the SCALE study group, Blackman, A., Foster, G. D., Zammit, G., Rosenberg, R., Aronne, L., Wadden, T., Claudius, B., Jensen, C. B., & Mignot, E. (2016) · International Journal of Obesity

Obstructive Sleep Apnea ResearchPharmacology and Obesity Treatment

Cited by 583

CSF hypocretin/orexin levels in narcolepsy and other neurological conditions

Ripley, B., Overeem, S., Fujiki, N., Nevsimalova, S., Uchino, M., Yesavage, J., Di Monte, D., Dohi, K., Melberg, A., Lammers, G. J., et al. (2001) · Neurology

Sleep and Wakefulness ResearchSleep and related disorders

Cited by 415

Concomitant loss of dynorphin, NARP, and orexin in narcolepsy

Crocker, A., España, R. A., Papadopoulou, M., Saper, C. B., Faraco, J., Sakurai, T., Honda, M., Mignot, E., & Scammell, T. E. (2005) · Neurology

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 301

Feasibility of Obtaining Measures of Lifestyle From a Smartphone App: The MyHeart Counts Cardiovascular Health Study

McConnell, M. V., Shcherbina, A., Pavlovic, A., Homburger, J. R., Goldfeder, R. L., Waggot, D., Cho, M. K., Rosenberger, M. E., Haskell, W. L., Myers, J., et al. (2017) · JAMA Cardiology

Mobile Health and mHealth ApplicationsPhysical Activity and Health

Cited by 239

Genetics of circadian rhythms and sleep in human health and disease

Lane, J. M., Qian, J., Mignot, E., Redline, S., Scheer, F. A. J. L., & Saxena, R. (2023) · Nature Reviews Genetics

Circadian rhythm and melatoninSleep and related disorders

Cited by 236

Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury

Baumann, C. R., Stocker, R., Imhof, H. G., Trentz, O., Hersberger, M., Mignot, E., & Bassetti, C. L. (2005) · Neurology

Sleep and Wakefulness ResearchTraumatic Brain Injury and Neurovascular Disturbances

Cited by 191

Correlates of Serum C-Reactive Protein (CRP) — No Association With Sleep Duration or Sleep Disordered Breathing

Taheri, S., Austin, D., Lin, L., Nieto, F. J., Young, T., & Mignot, E. (2007) · Sleep

Obstructive Sleep Apnea ResearchSleep and related disorders

Cited by 189

PER3 polymorphism predicts cumulative sleep homeostatic but not neurobehavioral changes to chronic partial sleep deprivation

Goel, N., Banks, S., Mignot, E., & Dinges, D. F. (2009) · PLoS ONE

Sleep and Work-Related FatigueSleep and Wakefulness Research

Cited by 154

Future of genetics of mood disorders research

Merikangas, K. R., Chakravarti, A., Moldin, S. O., Araj, H., Blangero, J., Burmeister, M., Crabbe, J. C., Depaulo, J. R., Foulks, E., Freimer, N. B., et al. (2002) · Biological Psychiatry

Genetic Associations and EpidemiologyBipolar Disorder and Treatment

Cited by 128

A link between short sleep and obesity: building the evidence for causation

Cizza, G., Skarulis, M., & Mignot, E. (2005) · SLEEP

Sleep and related disordersSleep and Wakefulness Research

Cited by 111

DQB1*0602 predicts interindividual differences in physiologic sleep, sleepiness, and fatigue

Goel, N., Banks, S., Mignot, E., & Dinges, D. F. (2010) · Neurology

Sleep and Wakefulness ResearchSleep and Work-Related Fatigue

Cited by 92

Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease

Katz, D. H., Tahir, U. A., Bick, A. G., Pampana, A., Ngo, D., Benson, M. D., Yu, Z., Robbins, J. M., Chen, Z.-Z., Cruz, D. E., et al. (2022) · Circulation

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 92

The immunopathogenesis of narcolepsy type 1

Liblau, R. S., Latorre, D., Kornum, B. R., Dauvilliers, Y., & Mignot, E. J. (2024) · Nature Reviews Immunology

Sleep and Wakefulness ResearchObstructive Sleep Apnea Research

Cited by 91

Catechol-O-methyltransferase Val158Met polymorphism associates with individual differences in sleep physiologic responses to chronic sleep loss

Goel, N., Banks, S., Lin, L., Mignot, E., & Dinges, D. F. (2011) · PLoS ONE

Sleep and Wakefulness ResearchSleep and Work-Related Fatigue

Cited by 58

Increasing length of wakefulness and modulation of hypocretin-1 in the wake-consolidated squirrel monkey

Zeitzer, J. M., Buckmaster, C. L., Lyons, D. M., & Mignot, E. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Sleep and Wakefulness ResearchSleep and Work-Related Fatigue

Cited by 31

Design of a deep learning model for automatic scoring of periodic and non-periodic leg movements during sleep validated against multiple human experts

Carvelli, L., Olesen, A. N., Brink-Kjær, A., Leary, E. B., Peppard, P. E., Mignot, E., Sørensen, H. B. D., & Jennum, P. (2020) · Sleep Medicine

Sleep and related disordersEEG and Brain-Computer Interfaces

Cited by 24