Genetics of circadian rhythms and sleep in human health and disease

Diagnostic and Statistical Manual of Mental Disorders

American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works

The mutational constraint spectrum quantified from variation in 141,456 humans

Karczewski, K. J., Francioli, L. C., Tiao, G., Cummings, B. B., Alföldi, J., Wang, Q., Collins, R. L., Laricchia, K. M., Ganna, A., Birnbaum, D. P., et al. (2020) · Nature · doi:10.1038/s41586-020-2308-7 · Cited by 9,434 · see citing works

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

Davey Smith, G., & Ebrahim, S. (2003) · International Journal of Epidemiology · doi:10.1093/ije/dyg070 · Cited by 5,882 · see citing works

An atlas of genetic correlations across human diseases and traits

ReproGen Consortium, Bulik-Sullivan, B., Psychiatric Genomics Consortium, Genetic Consortium for Anorexia Nervosa of the Wellcome Trust Case Control Consortium 3, Finucane, H. K., Anttila, V., Gusev, A., Day, F. R., Loh, P.-R., Duncan, L., et al. (2015) · Nature Genetics · doi:10.1038/ng.3406 · Cited by 4,255 · see citing works

Two-Process Model of Sleep Regulation

Binder, M. D., Hirokawa, N., & Windhorst, U. (2008) · Springer eBooks · doi:10.1007/978-3-540-29678-2_6166 · Cited by 3,895 · see citing works

International Classification of Sleep Disorders-Third Edition

Sateia, M. J. (2014) · Chest · doi:10.1378/chest.14-0970 · Cited by 3,860 · see citing works

Mendelian Randomization

Emdin, C. A., Khera, A. V., & Kathiresan, S. (2017) · JAMA · doi:10.1001/jama.2017.17219 · Cited by 3,637 · see citing works

Meta-Analysis of Quantitative Sleep Parameters From Childhood to Old Age in Healthy Individuals: Developing Normative Sleep Values Across the Human Lifespan

Ohayon, M. M., Carskadon, M. A., Guilleminault, C., & Vitiello, M. V. (2004) · Sleep · doi:10.1093/sleep/27.7.1255 · Cited by 3,349 · see citing works

Narcolepsy in orexin Knockout Mice

Chemelli, R. M., Willie, J. T., Sinton, C. M., Elmquist, J. K., Scammell, T., Lee, C., Richardson, J. A., Williams, S. C., Xiong, Y., Kisanuki, Y., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)81973-x · Cited by 3,095 · see citing works

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

Lin, L., Faraco, J., Li, R., Kadotani, H., Rogers, W., Lin, X., Qiu, X., de Jong, P. J., Nishino, S., & Mignot, E. (1999) · Cell · doi:10.1016/s0092-8674(00)81965-0 · Cited by 2,613 · see citing works

Sleep Health: Can We Define It? Does It Matter?

Buysse, D. J. (2014) · SLEEP · doi:10.5665/sleep.3298 · Cited by 2,607 · see citing works

Regularly Occurring Periods of Eye Motility, and Concomitant Phenomena, During Sleep

Aserinsky, E., & Kleitman, N. (1953) · Science · doi:10.1126/science.118.3062.273 · Cited by 2,488 · see citing works

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

Dibner, C., Schibler, U., & Albrecht, U. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135821 · Cited by 2,421 · see citing works

Adverse metabolic and cardiovascular consequences of circadian misalignment

Scheer, F. A. J. L., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808180106 · Cited by 2,351 · see citing works

Clock Mutants of Drosophila melanogaster

Konopka, R. J., & Benzer, S. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.9.2112 · Cited by 2,287 · see citing works

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

Panda, S., Antoch, M. P., Miller, B. H., Su, A. I., Schook, A. C., Straume, M., Schultz, P. G., Kay, S. A., Takahashi, J. S., & Hogenesch, J. B. (2002) · Cell · doi:10.1016/s0092-8674(02)00722-5 · Cited by 2,272 · see citing works

Central and Peripheral Circadian Clocks in Mammals

Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153128 · Cited by 2,265 · see citing works

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

DIAGRAM Consortium, Dupuis, J., GIANT Consortium, Global BPgen Consortium, Anders Hamsten on behalf of Procardis Consortium, the MAGIC investigators, Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., et al. (2010) · Nature Genetics · doi:10.1038/ng.520 · Cited by 2,166 · see citing works

Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat

Moore, R. Y., & Eichler, V. B. (1972) · Brain Research · doi:10.1016/0006-8993(72)90054-6 · Cited by 2,135 · see citing works

Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions

Stephan, F. K., & Zucker, I. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.6.1583 · Cited by 2,039 · see citing works

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

Balsalobre, A., Damiola, F., & Schibler, U. (1998) · Cell · doi:10.1016/s0092-8674(00)81199-x · Cited by 2,001 · see citing works

Resetting central and peripheral circadian oscillators in transgenic rats

Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R.-I., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., & Tei, H. (2000) · Science · doi:10.1126/science.288.5466.682 · Cited by 1,907 · see citing works

Cyclic variations in EEG during sleep and their relation to eye movements, body motility, and dreaming

Dement, W., & Kleitman, N. (1957) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(57)90088-3 · Cited by 1,876 · see citing works

Transplanted Suprachiasmatic Nucleus Determines Circadian Period

Ralph, M. R., Foster, R. G., Davis, F. C., & Menaker, M. (1990) · Science · doi:10.1126/science.2305266 · Cited by 1,853 · see citing works

Mutagenesis and Mapping of a Mouse Gene, <i>Clock</i> , Essential for Circadian Behavior

Vitaterna, M. H., King, D. P., Chang, A.-M., Kornhauser, J. M., Lowrey, P. L., McDonald, J. D., Dove, W. F., Pinto, L. H., Turek, F. W., & Takahashi, J. S. (1994) · Science · doi:10.1126/science.8171325 · Cited by 1,632 · see citing works

The genetics of mammalian circadian order and disorder: implications for physiology and disease

Takahashi, J. S., Hong, H.-K., Ko, C. H., & McDearmon, E. L. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2430 · Cited by 1,611 · see citing works

An h <i>Per2</i> Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome

Toh, K. L., Jones, C. R., He, Y., Eide, E. J., Hinz, W. A., Virshup, D. M., Ptáček, L. J., & Fu, Y.-H. (2001) · Science · doi:10.1126/science.1057499 · Cited by 1,460 · see citing works

Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans

Dijk, D., & Czeisler, C. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03526.1995 · Cited by 1,356 · see citing works

Guidelines for investigating causality of sequence variants in human disease

MacArthur, D. G., Manolio, T. A., Dimmock, D. P., Rehm, H. L., Shendure, J., Abecasis, G. R., Adams, D. R., Altman, R. B., Antonarakis, S. E., Ashley, E. A., et al. (2014) · Nature · doi:10.1038/nature13127 · Cited by 1,224 · see citing works

Health consequences of shift work and insufficient sleep

Kecklund, G., & Axelsson, J. (2016) · BMJ · doi:10.1136/bmj.i5210 · Cited by 1,195 · see citing works

Circadian physiology of metabolism

Panda, S. (2016) · Science · doi:10.1126/science.aah4967 · Cited by 1,092 · see citing works

A Phase Response Curve to Single Bright Light Pulses in Human Subjects

Khalsa, S. B. S., Jewett, M. E., Cajochen, C., & Czeisler, C. A. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.040477 · Cited by 1,040 · see citing works

A smartphone app reveals erratic diurnal eating patterns in humans that can be modulated for health benefits

Gill, S., & Panda, S. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.09.005 · Cited by 894 · see citing works

Functional consequences of a CKIδ mutation causing familial advanced sleep phase syndrome

Xu, Y., Padiath, Q. S., Shapiro, R. E., Jones, C. R., Wu, S. C., Saigoh, N., Saigoh, K., Ptáček, L. J., & Fu, Y.-H. (2005) · Nature · doi:10.1038/nature03453 · Cited by 861 · see citing works

Plant Circadian Rhythms

McClung, C. R. (2006) · The Plant Cell · doi:10.1105/tpc.106.040980 · Cited by 843 · see citing works

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

Jansen, P. R., Watanabe, K., Stringer, S., Skene, N., Bryois, J., Hammerschlag, A. R., de Leeuw, C., Benjamins, J. S., Muñoz‐Manchado, A. B., Nagel, M., et al. (2019) · Nature Genetics · doi:10.1038/s41588-018-0333-3 · Cited by 839 · see citing works

Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep

Vyazovskiy, V. V., Cirelli, C., Pfister-Genskow, M., Faraguna, U., & Tononi, G. (2008) · Nature Neuroscience · doi:10.1038/nn2035 · Cited by 837 · see citing works

Insomnia disorder

Morin, C. M., Drake, C. L., Harvey, A. G., Krystal, A. D., Manber, R., Riemann, D., & Spiegelhalder, K. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.26 · Cited by 746 · see citing works

Variants in MTNR1B influence fasting glucose levels

Prokopenko, I., Langenberg, C., Florez, J. C., Saxena, R., Soranzo, N., Þorleifsson, G., Loos, R. J. F., Manning, A. K., Jackson, A., Aulchenko, Y. S., et al. (2008) · Nature Genetics · doi:10.1038/ng.290 · Cited by 743 · see citing works

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

Lyssenko, V., Nagorny, C. L. F., Erdos, M. R., Wierup, N., Jonsson, A., Spégel, P., Bugliani, M., Saxena, R., Fex, M., Pulizzi, N., et al. (2009) · Nature Genetics · doi:10.1038/ng.288 · Cited by 742 · see citing works

A Length Polymorphism in the Circadian Clock Gene Per3 is Linked to Delayed Sleep Phase Syndrome and Extreme Diurnal Preference

Archer, S. N., Robilliard, D. L., Skene, D. J., Smits, M. G., Williams, A., Arendt, J., & von Schantz, M. (2003) · SLEEP · doi:10.1093/sleep/26.4.413 · Cited by 734 · see citing works

Insomnia and Risk of Cardiovascular Disease

Javaheri, S., & Redline, S. S. (2017) · CHEST Journal · doi:10.1016/j.chest.2017.01.026 · Cited by 731 · see citing works

Circadian Rhythms in Cultured Mammalian Retina

Tosini, G., & Menaker, M. (1996) · Science · doi:10.1126/science.272.5260.419 · Cited by 716 · see citing works

Sleep patterns, genetic susceptibility, and incident cardiovascular disease: a prospective study of 385 292 UK biobank participants

Fan, M., Sun, D., Zhou, T., Heianza, Y., Lv, J., Li, L., & Qi, L. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehz849 · Cited by 708 · see citing works

Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions

Winkelmann, J., Schormair, B., Lichtner, P., Ripke, S., Xiong, L., Jalilzadeh, S., Fulda, S., Pütz, B., Eckstein, G., Hauk, S., et al. (2007) · Nature Genetics · doi:10.1038/ng2099 · Cited by 705 · see citing works

Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms

Jones, S. E., Lane, J. M., Wood, A. R., van Hees, V. T., Tyrrell, J., Beaumont, R. N., Jeffries, A. R., Dashti, H. S., Hillsdon, M., Ruth, K. S., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-08259-7 · Cited by 691 · see citing works

A Genetic Risk Factor for Periodic Limb Movements in Sleep

Stefánsson, H., Rye, D. B., Hicks, A. A., Pétursson, H., Ingason, A., Thorgeirsson, T. E., Palsson, S., Sigmundsson, T., Sigurdsson, A. P., Eiríksdóttir, I., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa072743 · Cited by 630 · see citing works

Fatal Familial Insomnia, a Prion Disease with a Mutation at Codon 178 of the Prion Protein Gene

Medori, R., Tritschler, H., LeBlanc, A., Villare, F., Manetto, V., Chen, H. Y., Xue, R., Leal, S. M., Montagna, P., Cortelli, P., et al. (1992) · New England Journal of Medicine · doi:10.1056/nejm199202133260704 · Cited by 605 · see citing works

Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

Dashti, H. S., Jones, S. E., Wood, A. R., Lane, J. M., van Hees, V. T., Wang, H., Rhodes, J. A., Song, Y., Patel, K., Anderson, S. G., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-08917-4 · Cited by 595 · see citing works

Genetic and familial aspects of narcolepsy

Mignot, E. J.-M. (1998) · Neurology · doi:10.1212/wnl.50.2_suppl_1.s16 · Cited by 590 · see citing works

Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome

Möller-Levet, C. S., Archer, S. N., Bucca, G., Laing, E. E., Slak, A., Kabiljo, R., Lo, J. C. Y., Santhi, N., von Schantz, M., Smith, C. P., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1217154110 · Cited by 576 · see citing works

Familial advanced sleep-phase syndrome: a short-period circadian rhythm variant in humans

Jones, C. R., Campbell, S. S., Zone, S. E., Cooper, F., DeSano, A., Murphy, P. J., Jones, B., Czajkowski, L., & Ptček, L. J. (1999) · Nature Medicine · doi:10.1038/12502 · Cited by 567 · see citing works

Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain

Lehman, M. N., Silver, R., Gladstone, W., Kahn, R. M., Gibson, M., & Bittman, E. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-06-01626.1987 · Cited by 560 · see citing works

Genetic determinants of daytime napping and effects on cardiometabolic health

Dashti, H. S., Daghlas, I., Lane, J. M., Huang, Y., Udler, M. S., Wang, H., Ollila, H. M., Jones, S. E., Kim, J., Wood, A. R., et al. (2021) · Nature Communications · doi:10.1038/s41467-020-20585-3 · Cited by 556 · see citing works

Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: a soft clustering analysis

Udler, M. S., Kim, J., von Grotthuss, M., Bonàs-Guarch, S., Cole, J. B., Chiou, J., ISGC, C. D. A. O. B. O. M. A. T., Boehnke, M., Laakso, M., Atzmon, G., et al. (2018) · PLOS Medicine · doi:10.1371/journal.pmed.1002654 · Cited by 542 · see citing works

Idiopathic REM sleep behaviour disorder and neurodegeneration — an update

Högl, B., Stefani, A., & Videnović, A. (2017) · Nature Reviews Neurology · doi:10.1038/nrneurol.2017.157 · Cited by 542 · see citing works

Genomics of circadian rhythms in health and disease

Rijo‐Ferreira, F., & Takahashi, J. S. (2019) · Genome Medicine · doi:10.1186/s13073-019-0704-0 · Cited by 537 · see citing works

PER3 polymorphism predicts sleep structure and waking performance

Viola, A. U., Archer, S. N., James, L. M., Groeger, J. A., Lo, J. C. Y., Skene, D. J., von Schantz, M., & Dijk, D.-J. (2007) · Current Biology · doi:10.1016/j.cub.2007.01.073 · Cited by 520 · see citing works

Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome

Ebisawa, T., Uchiyama, M., Kajimura, N., Mishima, K., Kamei, Y., Katoh, M., Watanabe, T., Sekimoto, M., Shibui, K., Kim, K., et al. (2001) · EMBO Reports · doi:10.1093/embo-reports/kve070 · Cited by 517 · see citing works

Using genetic data to strengthen causal inference in observational research

Pingault, J.-B., O’Reilly, P. F., Schoeler, T., Ploubidis, G. B., Rijsdijk, F., & Dudbridge, F. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0020-3 · Cited by 444 · see citing works

Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms

Reddy, P., Zehring, W. A., Wheeler, D. A., Pirrotta, V., Hadfield, C., Hall, J. C., & Rosbash, M. (1984) · Cell · doi:10.1016/0092-8674(84)90265-4 · Cited by 423 · see citing works

GWAS identifies 14 loci for device-measured physical activity and sleep duration

Doherty, A., Smith-Byrne, K., Ferreira, T., Holmes, M. V., Holmes, C., Pulit, S. L., & Lindgren, C. M. (2018) · Nature Communications · doi:10.1038/s41467-018-07743-4 · Cited by 408 · see citing works

Biological and clinical insights from genetics of insomnia symptoms

Sleep, H. A. I., Lane, J. M., Jones, S. E., Dashti, H. S., Wood, A. R., Aragam, K. G., van Hees, V. T., Strand, L. B., Winsvold, B. S., Wang, H., et al. (2019) · Nature Genetics · doi:10.1038/s41588-019-0361-7 · Cited by 397 · see citing works

HLA DQB1*0602 is Associated With Cataplexy in 509 Narcoleptic Patients

Mignot, E. J.-M., Hayduk, R., Black, J. E., Grumet, F. C., & Guilleminault, C. (1997) · SLEEP · doi:10.1093/sleep/20.11.1012 · Cited by 394 · see citing works

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Gaulton, K. J., Ferreira, T. C., Lee, Y., Raimondo, A., Mägi, R., Reschen, M. E., Mahajan, A., Locke, A. E., Rayner, N. W., Robertson, N., et al. (2015) · Nature Genetics · doi:10.1038/ng.3437 · Cited by 390 · see citing works

Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci

Jones, S. E., Tyrrell, J., Wood, A. R., Beaumont, R. N., Ruth, K. S., Tuke, M. A., Yaghootkar, H., Hu, Y., Teder-Laving, M., Hayward, C., et al. (2016) · PLOS Genetics · doi:10.1371/journal.pgen.1006125 · Cited by 388 · see citing works

The genetic and molecular regulation of sleep: from fruit flies to humans

Cirelli, C. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2683 · Cited by 382 · see citing works

Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder

Patke, A., Murphy, P. J., Onat, O. E., Krieger, A. C., Özçelik, T., Campbell, S. S., & Young, M. W. (2017) · Cell · doi:10.1016/j.cell.2017.03.027 · Cited by 381 · see citing works

HLA antigens in Japanese patients with narcolepsy

Juji, T., Satake, M., Honda, Y., & Doi, Y. (1984) · Tissue Antigens · doi:10.1111/j.1399-0039.1984.tb02144.x · Cited by 373 · see citing works

Getting Through to Circadian Oscillators: Why Use Constant Routines?

Duffy, J. F., & Dijk, D.-J. (2002) · Journal of Biological Rhythms · doi:10.1177/074873002129002294 · Cited by 368 · see citing works

Aging and circadian rhythms

Duffy, J. F., Zitting, K.-M., & Chinoy, E. D. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2015.08.002 · Cited by 367 · see citing works

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

The Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC), Bonnefond, A., Clément, N., Fawcett, K., Yengo, L., Vaillant, E., Guillaume, J.-L., Dechaume, A., Payne, F., Roussel, R., et al. (2012) · Nature Genetics · doi:10.1038/ng.1053 · Cited by 363 · see citing works

The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals

He, Y., Jones, C. R., Fujiki, N., Xu, Y., Guo, B., Holder, J. L., Rossner, M. J., Nishino, S., & Fu, Y. (2009) · Science · doi:10.1126/science.1174443 · Cited by 346 · see citing works

Altered Brain iron homeostasis and dopaminergic function in Restless Legs Syndrome (Willis–Ekbom Disease)

Earley, C. J., Connor, J. R., Garcı́a-Borreguero, D., Jenner, P. G., Winkelman, J. W., Zee, P. C., & Allen, R. P. (2014) · Sleep Medicine · doi:10.1016/j.sleep.2014.05.009 · Cited by 338 · see citing works

Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits

Lane, J. M., Liang, J., Vlasac, I., Anderson, S. G., Bechtold, D. A., Bowden, J., Emsley, R., Gill, S., Little, M. A., Luik, A. I., et al. (2016) · Nature Genetics · doi:10.1038/ng.3749 · Cited by 337 · see citing works

Impact of Circadian Disruption on Cardiovascular Function and Disease

Chellappa, S. L., Vujović, N., Williams, J. S., & Scheer, F. A. J. L. (2019) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2019.07.008 · Cited by 333 · see citing works

Sleep states alter activity of suprachiasmatic nucleus neurons

Deboer, T., Vansteensel, M. J., Détári, L., & Meijer, J. H. (2003) · Nature Neuroscience · doi:10.1038/nn1122 · Cited by 324 · see citing works

GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person

Hu, Y., Shmygelska, A., Tran, D., Eriksson, N., Tung, J. Y., & Hinds, D. A. (2016) · Nature Communications · doi:10.1038/ncomms10448 · Cited by 321 · see citing works

A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine

Ruben, M. D., Wu, G., Smith, D. F., Schmidt, R. E., Francey, L. J., Lee, Y. Y., Anafi, R. C., & Hogenesch, J. B. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aat8806 · Cited by 314 · see citing works

Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank

Lane, J. M., Vlasac, I., Anderson, S. G., Kyle, S. D., Dixon, W. G., Bechtold, D. A., Gill, S., Little, M. A., Luik, A., Loudon, A., et al. (2016) · Nature Communications · doi:10.1038/ncomms10889 · Cited by 312 · see citing works

The future of sleep health: a data-driven revolution in sleep science and medicine

Perez-Pozuelo, I., Zhai, B., Palotti, J., Mall, R., Aupetit, M., Garcia-Gomez, J. M., Taheri, S., Guan, Y., & Fernandez-Luque, L. (2020) · npj Digital Medicine · doi:10.1038/s41746-020-0244-4 · Cited by 311 · see citing works

Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour

Jones, S. E., van Hees, V. T., Mazzotti, D. R., Marques-Vidal, P., Sabia, S., van der Spek, A., Dashti, H. S., Engmann, J., Kocevska, D., Tyrrell, J., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09576-1 · Cited by 300 · see citing works

Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits

Hammerschlag, A. R., Stringer, S., de Leeuw, C. A., Sniekers, S., Taskesen, E., Watanabe, K., Blanken, T. F., Dekker, K., te Lindert, B. H. W., Wassing, R., et al. (2017) · Nature Genetics · doi:10.1038/ng.3888 · Cited by 289 · see citing works

Narcolepsy

Kornum, B. R., Knudsen, S., Ollila, H. M., Pizza, F., Jennum, P., Dauvilliers, Y. A., & Overeem, S. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.100 · Cited by 284 · see citing works

Sleep Duration and Myocardial Infarction

Daghlas, I., Dashti, H. S., Lane, J. M., Aragam, K. G., Rutter, M. K., Saxena, R., & Vetter, C. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.07.022 · Cited by 282 · see citing works

Comorbidities, treatment, and pathophysiology in restless legs syndrome

Trenkwalder, C., Allen, R. P., Högl, B., Clemens, S., Patton, S. M., Schormair, B., & Winkelmann, J. (2018) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30311-9 · Cited by 275 · see citing works

Entrainment of the Human Circadian Clock

Roenneberg, T., & Merrow, M. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.043 · Cited by 272 · see citing works

Melatonin in type 2 diabetes mellitus and obesity

Karamitri, A., & Jockers, R. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-018-0130-1 · Cited by 268 · see citing works

The electroencephalographic fingerprint of sleep is genetically determined: A twin study

Gennaro, L. D., Marzano, C., Fratello, F., Moroni, F., Pellicciari, M. C., Ferlazzo, F., Costa, S., Couyoumdjian, A., Curcio, G., Sforza, E. A., et al. (2008) · Annals of Neurology · doi:10.1002/ana.21434 · Cited by 268 · see citing works

Increased melatonin signaling is a risk factor for type 2 diabetes

Tuomi, T., Nagorny, C. L. F., Singh, P., Bennet, H., Yu, Q., Alenkvist, I., Isomaa, B., Östman, B., Söderström, J., Pesonen, A.-K., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.04.009 · Cited by 262 · see citing works

Molecular genetics of a biological clock in Drosophila

Bargiello, T. A., & Young, M. W. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.7.2142 · Cited by 245 · see citing works

ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy

Faraco, J. H., Lin, L., Kornum, B. R., Kenny, E. E., Trynka, G., Einen, M. A., Rico, T., Lichtner, P., Dauvilliers, Y. A., Arnulf, I., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003270 · Cited by 244 · see citing works

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis

Schormair, B., Zhao, C., Bell, S., Tilch, E., Salminen, A. V., Pütz, B., Dauvilliers, Y. A., Stefani, A., Högl, B., Poewe, W. H., et al. (2017) · The Lancet Neurology · doi:10.1016/s1474-4422(17)30327-7 · Cited by 238 · see citing works

Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes

Wang, H., Lane, J. M., Jones, S. E., Dashti, H. S., Ollila, H. M., Wood, A. R., van Hees, V. T., Brumpton, B. M., Winsvold, B. S., Kantojärvi, K., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11456-7 · Cited by 235 · see citing works

GENETIC MARKERS IN NARCOLEPSY

Langdon, N., Dam, M., Welsh, K., Vaughan, R., & Parkes, D. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92742-9 · Cited by 217 · see citing works

Association of the Length Polymorphism in the Human Per3 Gene with the Delayed Sleep-Phase Syndrome: Does Latitude Have an Influence Upon It?

Pereira, D. S., Tufik, S. B., Louzada, F. M., Benedito‐Silva, A. A., Lopez, A. R., Lemos, N. A. M., Korczak, A., Vania D´Almeida, P., & Pedrazzoli, M. (2005) · SLEEP · doi:10.1093/sleep/28.1.29 · Cited by 212 · see citing works

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health

Strausz, S., Ruotsalainen, S., Ollila, H. M., Karjalainen, J., Kiiskinen, T., Reeve, M., Kurki, M., Mars, N., Havulinna, A. S., Luonsi, E., et al. (2021) · European Respiratory Journal · doi:10.1183/13993003.03091-2020 · Cited by 194 · see citing works

Melatonin effects on glucose metabolism: time to unlock the controversy

Garaulet, M., Qian, J., Florez, J. C., Arendt, J., Saxena, R., & Scheer, F. A. J. L. (2020) · Trends in Endocrinology &amp; Metabolism · doi:10.1016/j.tem.2019.11.011 · Cited by 193 · see citing works

Discovery and implications of polygenicity of common diseases

Visscher, P. M., Yengo, L., Cox, N. J., & Wray, N. R. (2021) · Science · doi:10.1126/science.abi8206 · Cited by 191 · see citing works

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

Hor, H., Kutalik, Z., Dauvilliers, Y. A., Valsesia, A., Lammers, G. J., Donjacour, C. E. H. M., Iranzo, Á., Santamaría, J., Peraita‐Adrados, R., Vicario, J. L., et al. (2010) · Nature Genetics · doi:10.1038/ng.647 · Cited by 189 · see citing works

Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy

Luo, G., Ambati, A., Lin, L., Bonvalet, M., Partinen, M., Ji, X., Maecker, H. T., & Mignot, E. J.-M. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1818150116 · Cited by 186 · see citing works

From variant to function in human disease genetics

Lappalainen, T., & MacArthur, D. G. (2021) · Science · doi:10.1126/science.abi8207 · Cited by 175 · see citing works

Transplantation of the neonatal suprachiasmatic nuclei into rats with complete bilateral suprachiasmatic lesions.

Sawaki, Y., Nihonmatsu, I., & Kawamura, H. (1984) · Neurosciences research · doi:10.1016/0168-0102(84)90031-2 · Cited by 172 · see citing works

A <i>PERIOD3</i> variant causes a circadian phenotype and is associated with a seasonal mood trait

Zhang, L., Hirano, A., Hsu, P.-K., Jones, C. R., Sakai, N., Okuro, M., McMahon, T., Yamazaki, M., Xu, Y., Saigoh, N., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1600039113 · Cited by 169 · see citing works

Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status

Rask‐Andersen, M., Karlsson, T., Ek, W. E., & Johansson, Å. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006977 · Cited by 166 · see citing works

Heritability of Sleep Electroencephalogram

Ambrosius, U., Lietzenmaier, S., Wehrle, R., Wichniak, A., Kalus, S., Winkelmann, J., Bettecken, T., Holsboer, F., Yassouridis, A., & Frieß, E. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.03.002 · Cited by 163 · see citing works

A Novel BHLHE41 Variant is Associated with Short Sleep and Resistance to Sleep Deprivation in Humans

Pellegrino, R., Kavaklı, İ. H., Goel, N., Cardinale, C. J., Dinges, D. F., Kuna, S. T., Maislin, G., Dongen, H. P. A. V., Tufik, S., Hogenesch, J. B., et al. (2014) · SLEEP · doi:10.5665/sleep.3924 · Cited by 161 · see citing works

Sleep and longitudinal cognitive performance in preclinical and early symptomatic Alzheimer’s disease

Lucey, B. P., Wisch, J. K., Boerwinkle, A. H., Landsness, E. C., Toedebusch, C. D., McLeland, J., Butt, O. H., Hassenstab, J. J., Morris, J. C., Ances, B. M., et al. (2021) · Brain · doi:10.1093/brain/awab272 · Cited by 161 · see citing works

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

Han, F., Faraco, J. H., Dong, X. S., Ollila, H. M., Lin, L., Li, J., An, P., Wang, S., Jiang, K. W., Gao, Z. C., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003880 · Cited by 160 · see citing works

Molecular Mechanisms of Sleep Homeostasis in Flies and MammalsPreprint

Allada, R., Cirelli, C., & Sehgal, A. (2017) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a027730 · Cited by 155 · see citing works

Genome-wide association study of sleep in Drosophila melanogaster

Harbison, S. T., McCoy, L. J., & Mackay, T. F. C. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-281 · Cited by 154 · see citing works

Prevalence of Circadian Misalignment and Its Association With Depressive Symptoms in Delayed Sleep Phase Disorder

Murray, J. M., Sletten, T. L., Magee, M., Gordon, C. J., Lovato, N., Bartlett, D. J., Kennaway, D. J., Lack, L. C., Grunstein, R. R., Lockley, S. W., et al. (2017) · SLEEP · doi:10.1093/sleep/zsw002 · Cited by 150 · see citing works

G-allele of Intronic rs10830963 inMTNR1BConfers Increased Risk of Impaired Fasting Glycemia and Type 2 Diabetes Through an Impaired Glucose-Stimulated Insulin Release

Sparsø, T., Bonnefond, A., Galijatovic, E. A. A., Bouatia‐Naji, N., Holmkvist, J., Thørner, L. W., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., et al. (2009) · Diabetes · doi:10.2337/db08-1660 · Cited by 146 · see citing works

Insomnia symptoms and risk of cardiovascular diseases among 0.5 million adults

Zheng, B., Yu, C., Lv, J., Guo, Y., Bian, Z., Zhou, M., Yang, L., Chen, Y., Li, X., Zou, J., et al. (2019) · Neurology · doi:10.1212/wnl.0000000000008581 · Cited by 139 · see citing works

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank

Campos, A. I., García‐Marín, L. M., Byrne, E. M., Martin, N. G., Cuéllar-Partida, G., & Rentería, M. E. (2020) · Nature Communications · doi:10.1038/s41467-020-14625-1 · Cited by 136 · see citing works

Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans

Cade, B. E., Chen, H., Stilp, A. M., Gleason, K. J., Sofer, T., Ancoli-Israel, S., Arens, R., Bell, G. I., Below, J. E., Bjonnes, A. C., et al. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201512-2431oc · Cited by 134 · see citing works

The relationship between depression and chronotype: A longitudinal assessment during childhood and adolescence

Haraden, D. A., Mullin, B. C., & Hankin, B. L. (2017) · Depression and Anxiety · doi:10.1002/da.22682 · Cited by 132 · see citing works

Genetics of restless legs syndrome: An update

Jiménez‐Jiménez, F. J., Alonso‐Navarro, H., García‐Martín, E., & Agúndez, J. A. G. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.08.002 · Cited by 128 · see citing works

Circadian Regulation of Diverse Gene Products Revealed by mRNA Expression Profiling of Synchronized Fibroblasts

Grundschober, C., Delaunay, F., Pühlhofer, A., Triqueneaux, G., Laudet, V., Bartfai, T., & Nef, P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107499200 · Cited by 127 · see citing works

Resetting the late timing of ‘night owls’ has a positive impact on mental health and performance

Facer‐Childs, E. R., Middleton, B., Skene, D. J., & Bagshaw, A. P. (2019) · Sleep Medicine · doi:10.1016/j.sleep.2019.05.001 · Cited by 126 · see citing works

Late dinner impairs glucose tolerance in MTNR1B risk allele carriers: A randomized, cross-over study

Lopez-Minguez, J., Saxena, R., Bandín, C., Scheer, F. A., & Garaulet, M. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2017.04.003 · Cited by 124 · see citing works

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Wood, A. R., Jonsson, A., Jackson, A. U., Wang, N., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., et al. (2017) · Diabetes · doi:10.2337/db16-1452 · Cited by 117 · see citing works

Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study

Gottlieb, D. J., Hek, K., Chen, T.-H., Watson, N. F., Eiríksdóttir, G., Byrne, E. M., Cornelis, M. C., Warby, S. C., Bandinelli, S., Cherkas, L. F., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.133 · Cited by 116 · see citing works

Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalonPreprint

Spieler, D., Kaffe, M., Knauf, F., Bessa, J., Tena, J. J., Giesert, F., Schormair, B., Tilch, E., Lee, H., Horsch, M., et al. (2014) · Genome Research · doi:10.1101/gr.166751.113 · Cited by 110 · see citing works

The genetics of obstructive sleep apnoea

Mukherjee, S., Saxena, R., & Palmer, L. J. (2017) · Respirology · doi:10.1111/resp.13212 · Cited by 110 · see citing works

Genetics of Circadian Rhythms

Andreani, T., Itoh, T. Q., Yildirim, E., Hwangbo, D., & Allada, R. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2015.08.007 · Cited by 109 · see citing works

Identifying advanced and delayed sleep phase disorders in the general population: A national survey of New Zealand adults

Paine, S., Fink, J., Gander, P. H., & Warman, G. R. (2014) · Chronobiology International · doi:10.3109/07420528.2014.885036 · Cited by 104 · see citing works

Two Pedigrees of Familial Advanced Sleep Phase Syndrome in Japan

Satoh, K., Mishima, K., Inoue, Y., Ebisawa, T., & Shimizu, T. (2003) · SLEEP · doi:10.1093/sleep/26.4.416 · Cited by 101 · see citing works

Common type 2 diabetes risk variant in MTNR1B worsens the deleterious effect of melatonin on glucose tolerance in humans

Garaulet, M., Gómez-Abellán, P., Rubio-Sastre, P., Madrid, J. A., Saxena, R., & Scheer, F. A. J. L. (2015) · Metabolism · doi:10.1016/j.metabol.2015.08.003 · Cited by 100 · see citing works

Recent advances in treatment for narcolepsy

Barateau, L., & Dauvilliers, Y. A. (2019) · Therapeutic Advances in Neurological Disorders · doi:10.1177/1756286419875622 · Cited by 100 · see citing works

Workshop report. Circadian rhythm sleep–wake disorders: gaps and opportunities

Duffy, J. F., Abbott, S. M., Burgess, H. J., Crowley, S. J., Emens, J. S., Epstein, L. J., Gamble, K. L., Hasler, B. P., Kristo, D. A., Malkani, R. G., et al. (2021) · SLEEP · doi:10.1093/sleep/zsaa281 · Cited by 98 · see citing works

Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology

Lane, J. M., Chang, A., Bjonnes, A., Aeschbach, D., Anderson, C., Cade, B. E., Cain, S. W., Czeisler, C. A., Gharib, S. A., Gooley, J. J., et al. (2016) · Diabetes · doi:10.2337/db15-0999 · Cited by 95 · see citing works

A Rare Mutation of β1-Adrenergic Receptor Affects Sleep/Wake Behaviors

Shi, G., Xing, L., Wu, D., Bhattacharyya, B. J., Jones, C. R., McMahon, T., Chong, S. Y. C., Chen, J., Coppola, G., Geschwind, D. H., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.07.026 · Cited by 90 · see citing works

Overview of Sleep and Circadian Rhythm Disorders in Parkinson Disease

Gros, P., & Videnović, A. (2019) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2019.09.005 · Cited by 87 · see citing works

A Longitudinal Twin Study of Insomnia Symptoms in Adults

Lind, M. J., Aggen, S. H., Kirkpatrick, R. M., Kendler, K. S., & Amstadter, A. B. (2015) · SLEEP · doi:10.5665/sleep.4982 · Cited by 84 · see citing works

Multiethnic Meta-Analysis Identifies <i>RAI1</i> as a Possible Obstructive Sleep Apnea–related Quantitative Trait Locus in Men

Chen, H., Cade, B. E., Gleason, K. J., Bjonnes, A. C., Stilp, A. M., Sofer, T., Conomos, M. P., Ancoli-Israel, S., Arens, R., Azarbarzin, A., et al. (2018) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2017-0237oc · Cited by 82 · see citing works

Genetic and Metabolic Characterization of Insomnia

Ban, H., Kim, S. C., Seo, J., Kang, H.-B., & Choi, J. K. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018455 · Cited by 80 · see citing works

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

Noordam, R., Bos, M. M., Wang, H., Winkler, T. W., Bentley, A. R., Kilpeläinen, T. O., de Vries, P. S., Sung, Y. J., Schwander, K., Cade, B. E., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12958-0 · Cited by 80 · see citing works

Interplay of Dinner Timing and <i>MTNR1B</i> Type 2 Diabetes Risk Variant on Glucose Tolerance and Insulin Secretion: A Randomized Crossover Trial

Garaulet, M., Lopez-Minguez, J., Dashti, H. S., Vetter, C., Hernández-Martínez, A. M., Pérez-Ayala, M., Baraza, J. C., Wang, W., Florez, J. C., Scheer, F. A. J. L., et al. (2022) · Diabetes Care · doi:10.2337/dc21-1314 · Cited by 77 · see citing works

DEC2 modulates orexin expression and regulates sleep

Hirano, A., Hsu, P.-K., Zhang, L., Xing, L., McMahon, T., Yamazaki, M., Ptáček, L. J., & Fu, Y. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1801693115 · Cited by 76 · see citing works

Genetically Proxied Diurnal Preference, Sleep Timing, and Risk of Major Depressive Disorder

Daghlas, I., Lane, J. M., Saxena, R., & Vetter, C. (2021) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2021.0959 · Cited by 76 · see citing works

Prospective study of chronotype and incident depression among middle- and older-aged women in the Nurses’ Health Study II

Vetter, C., Chang, S., Devore, E. E., Rohrer, F., Okereke, O. I., & Schernhammer, E. S. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.05.022 · Cited by 74 · see citing works

Sleep Duration and Body Mass Index in Twins: A Gene-Environment Interaction

Watson, N. F., Harden, K. P., Buchwald, D., Vitiello, M. V., Pack, A. I., Weigle, D. S., & Goldberg, J. H. (2012) · SLEEP · doi:10.5665/sleep.1810 · Cited by 72 · see citing works

Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability

Ferguson, A., Lyall, L. M., Ward, J., Strawbridge, R. J., Cullen, B., Graham, N., Niedzwiedz, C. L., Johnston, K. J. A., MacKay, D., Biello, S. M., et al. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.08.004 · Cited by 70 · see citing works

TIMELESS mutation alters phase responsiveness and causes advanced sleep phase

Kurien, P. A., Hsu, P.-K., de Leon, J. G., Wu, D., McMahon, T., Shi, G., Xu, Y., Lipzen, A., Pennacchio, L. A., Jones, C. R., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1819110116 · Cited by 70 · see citing works

Mutant neuropeptide S receptor reduces sleep duration with preserved memory consolidation

Xing, L., Shi, G., Mostovoy, Y., Gentry, N. W., Fan, Z., McMahon, T., Kwok, P., Jones, C. R., Ptáček, L. J., & Fu, Y. (2019) · Science Translational Medicine · doi:10.1126/scitranslmed.aax2014 · Cited by 69 · see citing works

Genome‐wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study

Spada, J., Scholz, M. R., Kirsten, H., Hensch, T., Horn, K., Jawinski, P., Ulke, C., Burkhardt, R., Wirkner, K., Loeffler, M., et al. (2016) · Journal of Sleep Research · doi:10.1111/jsr.12421 · Cited by 68 · see citing works

Genetics of Sleep and Insights into Its Relationship with Obesity

Dashti, H. S., & Ordovás, J. M. (2021) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-082018-124258 · Cited by 68 · see citing works

Genetics of narcolepsy

Miyagawa, T., & Tokunaga, K. (2019) · Human Genome Variation · doi:10.1038/s41439-018-0033-7 · Cited by 67 · see citing works

Replication of Genome‐Wide association studies ( GWAS ) loci for sleep in the British G1219 cohort

Parsons, M. J., Lester, K. J., Barclay, N. L., Nolan, P. M., Eley, T. C., & Gregory, A. M. (2013) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32106 · Cited by 64 · see citing works

Genetic Pathways to Insomnia

Lind, M. J., & Gehrman, P. (2016) · Brain Sciences · doi:10.3390/brainsci6040064 · Cited by 64 · see citing works

A systems genetics resource and analysis of sleep regulation in the mouse

Diessler, S., Jan, M., Emmenegger, Y., Guex, N., Middleton, B., Skene, D. J., Ibberson, M. R., Burdet, F., Götz, L., Pagni, M., et al. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2005750 · Cited by 61 · see citing works

HLA ‐ DQ association and allele competition in Chinese narcolepsy

Han, F., Lin, L., Li, J., Dong, S. X., An, P., Zhao, L. P., Liu, N. Y., Li, Q. Y., Yan, H., Gao, Z. C., et al. (2012) · Tissue Antigens · doi:10.1111/j.1399-0039.2012.01948.x · Cited by 59 · see citing works

Mouse Model for Protein Tyrosine Phosphatase D (PTPRD) Associations with Restless Leg Syndrome or Willis-Ekbom Disease and Addiction: Reduced Expression Alters Locomotion, Sleep Behaviors and Cocaine-Conditioned Place Preference

Drgonová, J., Walther, D. M., Wang, K. J., Hartstein, G. L., Lochte, B. C., Troncoso, J. C., Uetani, N., Iwakura, Y., & Uhl, G. R. (2015) · Molecular Medicine · doi:10.2119/molmed.2015.00017 · Cited by 59 · see citing works

Sleep characteristics modify the association of genetic predisposition with obesity and anthropometric measurements in 119,679 UK Biobank participants1–3

Celis-Morales, C. A., Lyall, D. M., Guo, Y., Steell, L., Llanas, D., Ward, J., Mackay, D., Biello, S. M., Bailey, M. E. S., Pell, J. P., et al. (2017) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.147231 · Cited by 58 · see citing works

Admixture mapping identifies novel loci for obstructive sleep apnea in Hispanic/Latino Americans

Wang, H., Cade, B. E., Sofer, T., Sands, S. A., Chen, H., Browning, S. R., Stilp, A. M., Louie, T. L., Thornton, T. A., Johnson, W. C., et al. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddy387 · Cited by 56 · see citing works

Childhood sleep duration modifies the polygenic risk for obesity in youth through leptin pathway: the Beijing Child and Adolescent Metabolic Syndrome cohort study

Fu, J., Wang, Y., Li, G., Han, L., Li, Y., Li, L., Feng, D., Wu, Y., Xiao, X., Li, M., et al. (2019) · International Journal of Obesity · doi:10.1038/s41366-019-0405-1 · Cited by 55 · see citing works

Genetic Risk of Alzheimer's Disease and Sleep Duration in Non‐Demented Elders

Leng, Y., Ackley, S. F., Glymour, M. M., Yaffe, K. S., & Brenowitz, W. D. (2020) · Annals of Neurology · doi:10.1002/ana.25910 · Cited by 55 · see citing works

Across the consciousness continuum—from unresponsive wakefulness to sleep

Blume, C., del Giudice, R., Wisłowska, M., Lechinger, J., & Schabus, M. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00105 · Cited by 52 · see citing works

Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures

Parsons, M. J., Lester, K. J., Barclay, N. L., Archer, S. N., Nolan, P. M., Eley, T. C., & Gregory, A. M. (2014) · Journal of Sleep Research · doi:10.1111/jsr.12144 · Cited by 52 · see citing works

Extreme morning chronotypes are often familial and not exceedingly rare: the estimated prevalence of advanced sleep phase, familial advanced sleep phase, and advanced sleep–wake phase disorder in a sleep clinic population

Curtis, B. J., Ashbrook, L. H., Young, T. B., Finn, L. A., Fu, Y., Ptáček, L. J., & Jones, C. R. (2019) · SLEEP · doi:10.1093/sleep/zsz148 · Cited by 50 · see citing works

Neurochemical features of idiopathic restless legs syndrome

Jiménez‐Jiménez, F. J., Alonso‐Navarro, H., García‐Martín, E., & Agúndez, J. A. G. (2019) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2019.03.006 · Cited by 50 · see citing works

Mutations in Metabotropic Glutamate Receptor 1 Contribute to Natural Short Sleep Trait

Shi, G., Chen, Y., Fan, Z., Xing, L., Mostovoy, Y., Kwok, P., Ashbrook, L. H., Krystal, A. D., Ptáček, L. J., & Fu, Y. (2020) · Current Biology · doi:10.1016/j.cub.2020.09.071 · Cited by 47 · see citing works

Shared genetic liability and causal effects between major depressive disorder and insomnia

Baranova, A. V., Cao, H., & Zhang, F. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddab328 · Cited by 47 · see citing works

Sleep disorders and Parkinson disease; lessons from genetics

Gan‐Or, Z., Alcalay, R. N., Rouleau, G. A., & Postuma, R. B. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2018.01.006 · Cited by 45 · see citing works

Using Mendelian Randomisation methods to understand whether diurnal preference is causally related to mental health

O’Loughlin, J., Casanova, F., Jones, S. E., Hagenaars, S. P., Beaumont, R. N., Freathy, R. M., Watkins, E. R., Vetter, C., Rutter, M. K., Cain, S. W., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01157-3 · Cited by 44 · see citing works

Chronotype Genetic Variant in PER2 is Associated with Intrinsic Circadian Period in Humans

Chang, A., Duffy, J. F., Buxton, O. M., Lane, J. M., Aeschbach, D., Anderson, C., Bjonnes, A., Cain, S. W., Cohen, D. A., Frayling, T. M., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-41712-1 · Cited by 43 · see citing works

Delayed sleep–wake phase disorder in young adults: prevalence and correlates from a national survey of Norwegian university students

Sivertsen, B., Harvey, A. G., Gradisar, M., Pallesen, S., & Hysing, M. (2020) · Sleep Medicine · doi:10.1016/j.sleep.2020.09.028 · Cited by 43 · see citing works

Comparison of Heritability Estimation and Linkage Analysis for Multiple Traits Using Principal Component Analyses

Liang, J., Cade, B. E., Wang, H., Chen, H., Gleason, K. J., Larkin, E. K., Saxena, R., Lin, X., Redline, S., & Zhu, X. (2016) · Genetic Epidemiology · doi:10.1002/gepi.21957 · Cited by 41 · see citing works

Genetic variants in RBFOX3 are associated with sleep latency

Amin, N., Allebrandt, K. V., van der Spek, A., Müller‐Myhsok, B., Hek, K., Teder‐Laving, M., Hayward, C., Esko, T., van Mill, J. G., Mbarek, H., et al. (2016) · European Journal of Human Genetics · doi:10.1038/ejhg.2016.31 · Cited by 40 · see citing works

Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium

Marinelli, M., Pappa, I., Bustamante, M., Bonilla, C., Bonilla, C., Suarez, A., Tiesler, C. M. T., Vilor‐Tejedor, N., Zafarmand, M. H., Álvarez‐Pedrerol, M., et al. (2016) · SLEEP · doi:10.5665/sleep.6170 · Cited by 40 · see citing works

Evolutionarily conserved regulation of sleep by epidermal growth factor receptor signaling

Lee, D. A., Liu, J., Hong, Y. K., Lane, J. M., Hill, A. J., Hou, S., Wang, H., Oikonomou, G., Pham, U., Engle, J., et al. (2019) · Science Advances · doi:10.1126/sciadv.aax4249 · Cited by 40 · see citing works

Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep

Cade, B. E., Chen, H., Stilp, A. M., Louie, T., Ancoli-Israel, S., Arens, R., Barfield, R., Below, J. E., Cai, J., Conomos, M. P., et al. (2019) · PLOS Genetics · doi:10.1371/journal.pgen.1007739 · Cited by 39 · see citing works

Correlation between HLA-DQB1*06:02 and narcolepsy with and without cataplexy: approving a safe and sensitive genetic test in four major ethnic groups. A systematic meta-analysis

Capittini, C., Silvestri, A. D., Terzaghi, M., Scotti, V., Rebuffi, C., Pasi, A., Manni, R., Martinetti, M., & Tinelli, C. (2018) · Sleep Medicine · doi:10.1016/j.sleep.2018.08.024 · Cited by 39 · see citing works

A human sleep homeostasis phenotype in mice expressing a primate‐specific PER3 variable‐number tandem‐repeat coding‐region polymorphism

Hasan, S., van der Veen, D. R., Winsky‐Sommerer, R., Hogben, A. L., Laing, E., Köentgen, F., Dijk, D., & Archer, S. N. (2014) · The FASEB Journal · doi:10.1096/fj.13-240135 · Cited by 37 · see citing works

Genetics of circadian rhythms

Vitaterna, M. H., Shimomura, K., & Jiang, P. (2019) · Neurologic Clinics · doi:10.1016/j.ncl.2019.05.002 · Cited by 36 · see citing works

Fxr1 regulates sleep and synaptic homeostasis

Khlghatyan, J., Evstratova, A., Bozoyan, L., Chamberland, S., Chatterjee, D., Marakhovskaia, A., Silva, T. S., Tóth, K., Mongrain, V., & Beaulieu, J. (2020) · The EMBO Journal · doi:10.15252/embj.2019103864 · Cited by 33 · see citing works

The Genetics of Sleep Disorders in Children: A Narrative Review

Mainieri, G., Montini, A., Nicotera, A. G., Rosa, G. D., Provini, F., & Loddo, G. (2021) · Brain Sciences · doi:10.3390/brainsci11101259 · Cited by 33 · see citing works

Rare missense mutations in P2RY11 in narcolepsy with cataplexy

Degn, M., Dauvilliers, Y. A., Dreisig, K., Lopez, R., Pfister, C., Pradervand, S., Kornum, B. R., & Tafti, M. (2017) · Brain · doi:10.1093/brain/awx093 · Cited by 33 · see citing works

Circadian preference and sleep timing from childhood to adolescence in relation to genetic variants from a genome-wide association study

Merikanto, I., Lahti, J. M. T., Kuula, L., Heinonen, K., Räikkönen, K., Andersson, S., Strandberg, T. E., & Pesonen, A. (2018) · Sleep Medicine · doi:10.1016/j.sleep.2018.04.015 · Cited by 27 · see citing works

The relationship between insomnia and complex diseases—insights from genetic data

Byrne, E. M. (2019) · Genome Medicine · doi:10.1186/s13073-019-0668-0 · Cited by 26 · see citing works

Lessons learned from the eMERGE Network: balancing genomics in discovery and practice

(2020) · Human Genetics and Genomics Advances · doi:10.1016/j.xhgg.2020.100018 · Cited by 26 · see citing works

Transcriptome-wide association study for restless legs syndrome identifies new susceptibility genes

Akçimen, F., Sarayloo, F., Liao, C., Ross, J. P., Oliveira, R. D. B., Dion, P. A., & Rouleau, G. A. (2020) · Communications Biology · doi:10.1038/s42003-020-1105-z · Cited by 25 · see citing works

Reassessing GWAS findings for the shared genetic basis of insomnia and restless legs syndrome

Gewely, M. E., Welman, M., Xiong, L., Yin, S., Catoire, H., Rouleau, G. A., Montplaisir, J. Y., Désautels, A., & Warby, S. C. (2018) · SLEEP · doi:10.1093/sleep/zsy164 · Cited by 24 · see citing works

Genome-wide association meta-analysis and Mendelian randomization analysis confirm the influence of ALDH2 on sleep durationin the Japanese population

Nishiyama, T., Nakatochi, M., Goto, A., Iwasaki, M., Hachiya, T., Sut­oh, Y., Shimizu, A., Wang, C., Tanaka, H., Watanabe, M., et al. (2019) · SLEEP · doi:10.1093/sleep/zsz046 · Cited by 24 · see citing works

Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure

Wang, H., Noordam, R., Cade, B. E., Schwander, K., Winkler, T. W., Lee, J., Sung, Y. J., Bentley, A. R., Manning, A. K., Aschard, H., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01087-0 · Cited by 23 · see citing works

Variants in angiopoietin-2 (ANGPT2) contribute to variation in nocturnal oxyhaemoglobin saturation level

Wang, H., Cade, B. E., Chen, H., Gleason, K. J., Saxena, R., Feng, T., Larkin, E. K., Vasan, R. S., Lin, H., Patel, S. R., et al. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw324 · Cited by 22 · see citing works

The genomic landscape of human cellular circadian variation points to a novel role for the signalosome

Gaspar, L., Howald, C., Popadin, K. Y., Maier, B., Mauvoisin, D., Moriggi, E., Gutiérrez‐Arcelus, M., Falconnet, E., Borel, C., Kunz, D., et al. (2017) · eLife · doi:10.7554/elife.24994 · Cited by 22 · see citing works

Sequencing Analysis at 8p23 Identifies Multiple Rare Variants in DLC1 Associated with Sleep-Related Oxyhemoglobin Saturation Level

Liang, J., Cade, B. E., He, K. Y., Wang, H., Lee, J., Sofer, T., Williams, S., Li, R., Chen, H., Gottlieb, D. J., et al. (2019) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2019.10.002 · Cited by 21 · see citing works

Narcolepsy type 1: what have we learned from genetics?

Ollila, H. M. (2020) · SLEEP · doi:10.1093/sleep/zsaa099 · Cited by 14 · see citing works

SKOR1 has a transcriptional regulatory role on genes involved in pathways related to restless legs syndrome

Sarayloo, F., Spiegelman, D., Rochefort, D. L., Akçimen, F., Oliveira, R. D. B., Dion, P. A., & Rouleau, G. A. (2020) · European Journal of Human Genetics · doi:10.1038/s41431-020-0670-4 · Cited by 14 · see citing works

Identification of Genes Contributing to a Long Circadian Period in Drosophila Melanogaster

Kumar, S., Tunc, I., Tansey, T. R., Pirooznia, M., & Harbison, S. T. (2020) · Journal of Biological Rhythms · doi:10.1177/0748730420975946 · Cited by 13 · see citing works

Orexin cell transplant reduces behavioral arrest severity in narcoleptic mice

Equihua-Benítez, A. C., Benítez, J. E., Guzmán-Vásquez, K., Prospero-Garcia, O. E., & Drucker-Colı́n, R. (2020) · Brain Research · doi:10.1016/j.brainres.2020.146951 · Cited by 10 · see citing works

Genome-wide meta-analysis of insomnia in over 2.3 million individuals implicates involvement of specific biological pathways through gene-prioritizationPreprint

Watanabe, K., Jansen, P. R., Savage, J. E., Nandakumar, P., Wang, X., Hinds, D. A., Gelernter, J. E., Levey, D. F., Polimanti, R. A., Stein, M. B., et al. (2020) · medRxiv · doi:10.1101/2020.12.07.20245209 · Cited by 10 · see citing works

The impact of Mendelian sleep and circadian genetic variants in a population setting

Weedon, M. N., Jones, S. E., Lane, J. M., Lee, J., Ollila, H. M., Dawes, A., Tyrrell, J., Beaumont, R. N., Partonen, T., Merikanto, I., et al. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010356 · Cited by 10 · see citing works

The Genetics of Sleep: Insight from Rodent Models

Summa, K. C., & Turek, F. W. (2011) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2011.04.004 · Cited by 8 · see citing works

Sleep Pharmacogenetics: The Promise of Precision Medicine.

Krystal, A., & Prather, A. (2019) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2019.05.003 · Cited by 6 · see citing works

Genetic Mechanisms Underlying SleepPreprint

Toda, H., Shi, M., Williams, J. A., & Sehgal, A. (2018) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2018.83.037705 · Cited by 3 · see citing works

Sleep and Oxidative Stress: Current Perspectives on the Role of NRF2

Davinelli, S., Medoro, A., Savino, R., & Scapagnini, G. (2024) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-024-01487-0 · Cited by 130 · see citing works

Effects of exercise on circadian rhythms in humans

Shen, B., Ma, C., Wu, G., Liu, H., Chen, L., & Yang, G. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1282357 · Cited by 125 · see citing works

Chronobiology and Chronomedicine

Gonçalves, C. F., & Meng, Q. (2024) · Royal Society of Chemistry eBooks · doi:10.1039/9781839167553 · Cited by 118 · see citing works

Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension - 2021 NHLBI Workshop Report

Gumz, M. L., Shimbo, D., Abdalla, M., Balijepalli, R. C., Benedict, C., Chen, Y., Earnest, D. J., Gamble, K. L., Garrison, S., Gong, M. C., et al. (2022) · Hypertension · doi:10.1161/hypertensionaha.122.19372 · Cited by 103 · see citing works

Acetate enables metabolic fitness and cognitive performance during sleep disruption

He, Q., Ji, L., Wang, Y., Zhang, Y., Wang, H., Wang, J., Zhu, Q., Xie, M., Ou, W., Liu, J., et al. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.07.019 · Cited by 103 · see citing works

Circadian Disruption and Mental Health: The Chronotherapeutic Potential of Microbiome-Based and Dietary Strategies

Codoñer‐Franch, P., Gombert, M., Martı́nez-Raga, J., & Cénit, M. C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087579 · Cited by 69 · see citing works

Intermittent fasting and cardiovascular health: a circadian rhythm-based approach

Zhang, J., Chen, Y., Zhong, Y., Wang, Y., Huang, H., Xu, W. L., Pan, W., Chen, L., Zhu, Y., Bischof, E. Y., et al. (2025) · 中国科学通报：英文版 · doi:10.1016/j.scib.2025.05.017 · Cited by 60 · see citing works

Postoperative Delirium and the Older Adult: Untangling the Confusion

Thedim, M., & Vacas, S. (2024) · Journal of Neurosurgical Anesthesiology · doi:10.1097/ana.0000000000000971 · Cited by 57 · see citing works

Revolutionizing Sleep Health: The Emergence and Impact of Personalized Sleep Medicine

Garbarino, S., & Bragazzi, N. L. (2024) · Journal of Personalized Medicine · doi:10.3390/jpm14060598 · Cited by 49 · see citing works

Cardiovascular health and cancer mortality: evidence from US NHANES and UK Biobank cohort studies

Lin, L., Hu, Y., Lei, F., Huang, X., Zhang, X., Sun, T., Liu, W., Li, R., Zhang, X., Cai, J., et al. (2024) · BMC Medicine · doi:10.1186/s12916-024-03553-2 · Cited by 49 · see citing works

Chronotherapy in Glioblastoma: state of the art and future perspectives

Petković, M., Henis, M., Heese, O., & Relógio, A. (2023) · EBioMedicine · doi:10.1016/j.ebiom.2023.104470 · Cited by 48 · see citing works

Biorhythm-mimicking growth hormone patch

Han, J., Wu, Z., Zhan, S., Sheng, T., You, J., Yu, J., Fu, J., Zhang, Y., & Gu, Z. (2025) · Nature Materials · doi:10.1038/s41563-025-02188-9 · Cited by 47 · see citing works

Sleep, Sleep Disorders, and Mental Health: A Narrative Review

Howarth, N. E., & Miller, M. A. (2024) · Heart and Mind · doi:10.4103/hm.hm-d-24-00030 · Cited by 46 · see citing works

Circadian biology to advance therapeutics for mood disorders

Bhatnagar, A., Murray, G., & Ray, S. (2023) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2023.07.008 · Cited by 40 · see citing works

The role of circadian rhythm regulator PERs in oxidative stress, immunity, and cancer development

Zhao, B., Nepovimová, E., & Wu, Q. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02040-2 · Cited by 38 · see citing works

Circadian regulation of liver metabolism: experimental approaches in human, rodent, and cellular models

Daniels, L. J., Kay, D., Marjot, T., Hodson, L., & Ray, D. W. (2023) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00551.2022 · Cited by 31 · see citing works

Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis

Liu, C., Li, S., Ji, S., Zhang, J., Zheng, F., Guan, Y., Yang, G., & Chen, L. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2022.166572 · Cited by 28 · see citing works

A good night's rest: A contemporary review of sleep and cardiovascular health

Amin, K. D., Thakkar, A., Budampati, T., Matai, S., Akkaya, E., & Shah, N. P. (2024) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2024.100924 · Cited by 27 · see citing works

New hints for improving sleep: Tea polyphenols mediate gut microbiota to regulate circadian disturbances

Xiang, Q., Liu, Y., Wu, Z., Wang, R., & Zhang, X. (2023) · Food Frontiers · doi:10.1002/fft2.199 · Cited by 27 · see citing works

Sleep condition detection and assessment with optical fiber interferometer based on machine learning

Wang, Q., Lyu, W., Zhou, J. H., & Yu, C. (2023) · iScience · doi:10.1016/j.isci.2023.107244 · Cited by 25 · see citing works

The missing hallmark of health: psychosocial adaptation

López-Otı́n, C., & Kroemer, G. (2024) · Cell Stress · doi:10.15698/cst2024.03.294 · Cited by 24 · see citing works

Circadian rhythm disruption and endocrine-related tumors

Savvidis, C., Kallistrou, E., Kouroglou, E., Dionysopoulou, S., Gavriiloglou, G., Ragia, D., Tsiama, V., Proikaki, S., Belis, K., & Ilias, Ι. (2024) · World Journal of Clinical Oncology · doi:10.5306/wjco.v15.i7.818 · Cited by 23 · see citing works

A new time dimension in the fight against metastasis

Diamantopoulou, Z., Gvozdenovic, A., & Aceto, N. (2023) · Trends in Cell Biology · doi:10.1016/j.tcb.2023.02.002 · Cited by 23 · see citing works

Selection of genetic instruments in Mendelian randomisation studies of sleep traits

Paz, V., Dashti, H. S., Burgess, S., & Garfield, V. (2023) · Sleep Medicine · doi:10.1016/j.sleep.2023.10.036 · Cited by 23 · see citing works

The multifaceted impact of circadian disruption on cancer risk: a systematic review of insights and economic implications

Clemente‐Suárez, V. J., Navarro-Jiménez, E., Benítez-Agudelo, J. C., Beltrán-Velasco, A. I., Belinchón-deMiguel, P., Ramos‐Campo, D. J., Villanueva-Tobaldo, C. V., Martín-Rodríguez, A., & Tornero-Aguilera, J. F. (2025) · Journal of the National Cancer Center · doi:10.1016/j.jncc.2025.04.005 · Cited by 22 · see citing works

Chrononutrition during Pregnancy and Its Association with Maternal and Offspring Outcomes: A Systematic Review and Meta-Analysis of Ramadan and Non-Ramadan Studies

Chen, Y.-E., Loy, S. L., & Chen, L. (2023) · Nutrients · doi:10.3390/nu15030756 · Cited by 22 · see citing works

Exome sequencing identifies genes associated with sleep-related traits

Fei, C.-J., Li, Z.-Y., Ning, J., Yang, L., Wu, B., Kang, J., Liu, W., He, X., You, J., Chen, S.-D., et al. (2024) · Nature Human Behaviour · doi:10.1038/s41562-023-01785-5 · Cited by 22 · see citing works

Dissemination of circulating tumor cells at night: role of sleep or circadian rhythm?

Dauvilliers, Y. A., Frédéric Thomas, A., & Alix‐Panabières, C. (2022) · Genome biology · doi:10.1186/s13059-022-02791-y · Cited by 21 · see citing works

Homeostatic control of deep sleep and molecular correlates of sleep pressure in Drosophila

Chowdhury, B., Abhilash, L., Ortega, A., Liu, S., & Shafer, O. T. (2023) · eLife · doi:10.7554/elife.91355 · Cited by 20 · see citing works

Chinese formula Guben-Jiannao Ye alleviates the dysfunction of circadian and sleep rhythms in APP/PS1 mice implicated in activation of the PI3K/AKT/mTOR signaling pathway

Mao, J.-Q., Cheng, L., Zhang, Y.-D., Xie, G., & Wang, P. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118696 · Cited by 19 · see citing works

Genome-wide association analysis of composite sleep health scores in 413,904 individuals

Goodman, M. O., Faquih, T. O., Paz, V., Nagarajan, P., Lane, J. M., Spitzer, B., Maher, M., Chung, J., Cade, B. E., Purcell, S., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-07514-0 · Cited by 19 · see citing works

Oxidative stress in the RVLM mediates sympathetic hyperactivity induced by circadian disruption

Duan, W., Ye, P., Leng, Y.-Q., Liu, D.-H., Sun, J., Tan, X. L., & Wang, W. (2022) · Neuroscience Letters · doi:10.1016/j.neulet.2022.136917 · Cited by 19 · see citing works

The Genetics of Human Sleep and Sleep Disorders

Zou, X., Ptáček, L. J., & Fu, Y. (2024) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-121222-120306 · Cited by 19 · see citing works

Divergent biological pathways linking short and long sleep durations to mental and physical health

Li, Y., Gong, W., Sahakian, B. J., Huang, S., Zhang, W., Zhao, Y., Ma, L., Naismith, S. L., Yu, J., Jia, T., et al. (2025) · Nature Mental Health · doi:10.1038/s44220-025-00395-6 · Cited by 18 · see citing works

Roles of circadian clocks in macrophage metabolism: implications in inflammation and metabolism of lipids, glucose, and amino acids

Dar, M. I., Hussain, Y., & Pan, X. (2025) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00009.2025 · Cited by 18 · see citing works

Potential of Polyphenols for Improving Sleep: A Preliminary Results from Review of Human Clinical Trials and Mechanistic Insights

Hibi, M. (2023) · Nutrients · doi:10.3390/nu15051257 · Cited by 18 · see citing works

Poor sleep quality in schizophrenia patients: A systematic review and meta-analyses of epidemiological and case-control studies

Chen, M.-Y., Wang, Y., Si, T. L., Liu, Y.-F., Su, Z., Cheung, T. C. C., Ungvari, G. S., Jackson, T., Zhang, Q., & Xiang, Y. (2024) · Schizophrenia Research · doi:10.1016/j.schres.2024.01.011 · Cited by 17 · see citing works

Chronotype in college science students is associated with behavioral choices and can fluctuate across a semester

Barley, B. K., Gao, C., Luster, T. G., Porro, A., Parizi‐Robinson, M., Quigley, D., Zinke, P., & Scullin, M. K. (2023) · Chronobiology International · doi:10.1080/07420528.2023.2203251 · Cited by 17 · see citing works

Narcolepsy and cardiovascular disease: A two-sample Mendelian randomization study

Tao, Y., Luo, J., Xu, Y., Wang, H., Tian, J., Yang, S., Yu, K., Peng, S., & Zhang, X. (2023) · Sleep Medicine · doi:10.1016/j.sleep.2023.10.029 · Cited by 16 · see citing works

Differential benefits of 12-week morning vs. evening aerobic exercise on sleep and cardiometabolic health: a randomized controlled trial

Shen, B., Zheng, H., Liu, H., Chen, L., & Yang, G. (2025) · Scientific Reports · doi:10.1038/s41598-025-02659-8 · Cited by 15 · see citing works

Sleep Deprivation Activates a Conserved Lactate‐H3K18la‐RORα Axis Driving Neutrophilic Inflammation Across Species

Zhou, R., Li, K., Hu, X., Fan, S., Gao, Y., Xue, X., Bu, Y., Zhang, H.-Y., Wang, Y., Wei, C., et al. (2025) · Advanced Science · doi:10.1002/advs.202504028 · Cited by 15 · see citing works

Non-pharmaceutical interventions to optimize cancer immunotherapy

Boesch, M., Baty, F., Rassouli, F., Kowatsch, T., Joerger, M., Früh, M., & Brutsche, M. H. (2023) · OncoImmunology · doi:10.1080/2162402x.2023.2255459 · Cited by 15 · see citing works

The influence of light on elasmobranch behavior and physiology: a review

Carroll, D., & Harvey‐Carroll, J. (2023) · Frontiers in Marine Science · doi:10.3389/fmars.2023.1225067 · Cited by 15 · see citing works

Circadian protein expression patterns in healthy young adults

Specht, A., Kolosov, G., Cederberg, K. L. J., Bueno, F. F., Arrona‐Palacios, A., Pardilla‐Delgado, E., Herrera, N. R., Zitting, K., Kramer, A., Zeitzer, J. M., et al. (2023) · Sleep Health · doi:10.1016/j.sleh.2023.10.005 · Cited by 15 · see citing works

Calcineurin governs baseline and homeostatic regulations of non–rapid eye movement sleep in mice

Yin, X., Zhang, Z., Zhou, R., Zuo, P., Sang, D., Zhou, S., Shi, B., Chen, L., Wu, C., Guo, Y., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2418317122 · Cited by 15 · see citing works

Night shift work, sleep duration and endometrial cancer risk: A pooled analysis from the Epidemiology of Endometrial Cancer Consortium (E2C2)

Frias‐Gomez, J., Alemany, L., Benavente, Y., Clarke, M. A., de Francisco, J., Vivo, I. D., Du, M., Goodman, M. T., Lacey, J. V., Liao, L. M., et al. (2023) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2023.101848 · Cited by 14 · see citing works

CRY1/2 regulate rhythmic CYP2A5 in mouse liver through repression of E4BP4

Lin, L., Huang, Y., Wang, J., Guo, X., Yu, F., He, D., Wu, C., Guo, L., & Wu, B. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115843 · Cited by 14 · see citing works

Therapeutic nuclear magnetic resonance and intermittent hypoxia trigger time dependent on/off effects in circadian clocks and confirm a central role of superoxide in cellular magnetic field effects

Thöni, V., Dimova, E. Y., Kietzmann, T., Usselman, R. J., & Egg, M. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103152 · Cited by 14 · see citing works

Validation of intrinsic capacity and healthy sleep pattern in middle-aged and older adults: a longitudinal Chinese study assessing healthy ageing

Chen, X.-L., Li, J., Sun, S., Zhang, X., Chen, J., Wang, L., Yang, Z.-Q., Ni, S.-H., & Lu, L. (2024) · The journal of nutrition health & aging · doi:10.1016/j.jnha.2024.100365 · Cited by 14 · see citing works

Platform-independent estimation of human physiological time from single blood samples

Huang, Y., & Braun, R. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2308114120 · Cited by 14 · see citing works

Health risks and genetic architecture of objectively measured multidimensional sleep health

Zhang, S., Zhang, M., Yuan, Y., Li, Z., Li, X., & Li, X. (2025) · Nature Communications · doi:10.1038/s41467-025-62338-0 · Cited by 13 · see citing works

Circadian rhythm, hypoxia, and cellular senescence: From molecular mechanisms to targeted strategies

Nie, T., Nepovimová, E., & Wu, Q. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177290 · Cited by 13 · see citing works

Monitoring Sleep Quality Through Low α-Band Activity in the Prefrontal Cortex Using a Portable Electroencephalogram Device: Longitudinal Study

Han, C., Zhang, Z., Lin, Y., Huang, S., Mao, J., Xiang, W., Wang, F., Liang, Y., Chen, W., & Zhao, X. (2025) · Journal of Medical Internet Research · doi:10.2196/67188 · Cited by 13 · see citing works

Regulation of testosterone synthesis by circadian clock genes and its research progress in male diseases

Ning, G., Li, B.-N., Wu, H. B. K., Shi, R.-B., Peng, A.-J., Wang, H., & Zhou, X. W. (2025) · Asian Journal of Andrology · doi:10.4103/aja20258 · Cited by 13 · see citing works

Effects of sex, mating status, and genetic background on circadian behavior in Drosophila

Akpoghiran, O., Strich, A. K., & Koh, K. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1532868 · Cited by 12 · see citing works

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Zheng, F., Liu, S., Tian, W., Wang, L., Chang, Y., Qu, H., & Zheng, L. (2025) · Science Advances · doi:10.1126/sciadv.adr8592 · Cited by 12 · see citing works

Self-Reported Sleep Disturbance is an Independent Predictor of All-Cause Mortality and Respiratory Disease Mortality in US Adults: A Population-Based Prospective Cohort Study

Hou, X., Hu, J., Wang, E., Wang, J., Song, Z., Hu, J. H., Shi, J., & Zhang, C. (2023) · International Journal of Public Health · doi:10.3389/ijph.2023.1605538 · Cited by 12 · see citing works

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Mu, C., Rho, J. M., & Shearer, J. (2025) · Advanced Science · doi:10.1002/advs.202504249 · Cited by 11 · see citing works

How Sleep Research in Extreme Environments Can Inform the Military: Advocating for a Transactional Model of Sleep Adaptation

van den Berg, N., Michaud, X., Pattyn, N., & Simonelli, G. (2023) · Current Psychiatry Reports · doi:10.1007/s11920-022-01407-3 · Cited by 11 · see citing works

Correlations in sleeping patterns and circadian preference between spouses

Richmond, R. C., Howe, L. J., Heilbron, K., Jones, S. E., Liu, J., Aslibekyan, S. W., Auton, A., Babalola, E., Bell, R. K., Bielenberg, J., et al. (2023) · Communications Biology · doi:10.1038/s42003-023-05521-7 · Cited by 10 · see citing works

Comprehensive integrative analysis of circadian rhythms in human saliva

Nelson, N., Malhan, D., Hesse, J., Aboumanify, O., Yalçın, M., Lüers, G. H., & Relógio, A. (2025) · npj Biological Timing and Sleep · doi:10.1038/s44323-025-00035-3 · Cited by 10 · see citing works

Biological rhythms are correlated with Na+, K+-ATPase and oxidative stress biomarkers: A translational study on bipolar disorder

Valvassori, S. S., Peper‐Nascimento, J., Aguiar‐Geraldo, J. M., Hilsendeger, A., Daminelli, T., Juruena, M. F., El‐Mallakh, R. S., & Quevedo, J. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.08.042 · Cited by 10 · see citing works

Sleep deprivation reduces the baroreflex sensitivity through elevated angiotensin (Ang) II subtype 1 receptor expression in the nucleus tractus solitarii

Liu, L., Wang, Y.-W., Sun, J., Wang, Y., Tan, X. L., & Wang, W.-Z. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1401530 · Cited by 9 · see citing works

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Pandi-Perumal, S. R., Paul, S., Saravanan, K. M., Pandian, G. N., & Chidambaram, S. B. (2024) · Current Molecular Medicine · doi:10.2174/0115665240305615240630113434 · Cited by 9 · see citing works

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Haaning, A., Sandri, B. J., Wyneken, H. L., Goldsmith, W. T., Nixon, J. P., Nurkiewicz, T. R., Wendt, C. H., Barach, P. R., Trembley, J. H., & Butterick, T. A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157238 · Cited by 9 · see citing works

An Autonomous Sleep-Stage Detection Technique in Disruptive Technology Environment

Radhakrishnan, B., Ezra, K., Jebadurai, I. J., Selvakumar, A. I., & Karthikeyan, P. (2024) · Sensors · doi:10.3390/s24041197 · Cited by 9 · see citing works

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Das, S., Khan, R., Banerjee, S., Ray, S., & Ray, S. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04178-5 · Cited by 9 · see citing works

Relationship Between Sleep Disturbances and In Vitro Fertilization Outcomes in Infertile Women: A Systematic Review and Meta‐Analysis

Habibi, F., Nikbakht, R., Jahanfar, S., Ahmadi, M., Eslami, M., Azizi, M., & Shahhosseini, Z. (2025) · Brain and Behavior · doi:10.1002/brb3.70293 · Cited by 8 · see citing works

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Samson, D. R., & McKinnon, L. (2025) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2024.2319 · Cited by 8 · see citing works

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Deng, Z., Zhao, L., Li, X., Wang, C., Zhou, Y., Li, M., Li, Y., & Fu, X. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115457 · Cited by 8 · see citing works

Photobiology: introduction, overview and challenges

Leister, D. (2023) · Frontiers in Photobiology · doi:10.3389/fphbi.2023.1253330 · Cited by 8 · see citing works

Sex/Gender Differences in Sleep Physiology and Sleep Disorders

Lee, H. W. (2024) · Springer eBooks · doi:10.1007/978-981-97-0130-8_27 · Cited by 8 · see citing works

An artificial intelligence powered study of enlarged facial pore prevalence on one million Chinese from different age groups and its correlation with environmental factors

Zhou, H., Xie, H., Wu, L., Song, J., Ma, Z., Zeng, D., Wang, X., Shi, S., Qu, Y., Luo, Y., et al. (2024) · Skin Research and Technology · doi:10.1111/srt.70025 · Cited by 7 · see citing works

Managing Blue Light Exposure: Impacts on Sleep Quality and Circadian Health

Grzelak, A. (2024) · Quality in Sport · doi:10.12775/qs.2024.25.56741 · Cited by 7 · see citing works

Intra- and inter-individual variation of the human lipidome

Anh, N. H., Beyene, H. B., Mocciaro, G., Hahnefeld, L., Lamichhane, S., Fabritius, M., Avela, H. F., Wang, Y., Dickens, A. M., Gurke, R., et al. (2025) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2025.118368 · Cited by 7 · see citing works

Circadian disruption induces cognitive impairment through tryptophan-5-HT metabolic pathway dysregulation

Liao, J., Wang, Y., Li, J., Li, P., Liu, Y., Wu, J., Zhao, M., Huang, H., Liu, P., Chen, Y., et al. (2025) · SLEEP · doi:10.1093/sleep/zsaf258 · Cited by 7 · see citing works

C‐X‐C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8 + T cells within the tumor microenvironment

Tsuruta, A., Fujimoto, M., Hiraoka, Y., Taniguchi, A., Shiiba, Y., Inoki, T., Yamauchi, T., Yoshida, Y., Matsunaga, N., Ohdo, S., et al. (2025) · International Journal of Cancer · doi:10.1002/ijc.70252 · Cited by 7 · see citing works

Disruption in the regulation of casein kinase 2 in circadian rhythm leads to pathological states: cancer, diabetes and neurodegenerative disorders

Malik, M. Z., DASHTI, M. H., Fatima, Y., Channanath, A. M., John, S. E., Singh, R. K. B., Al‐Mulla, F., & Thanaraj, T. A. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1217992 · Cited by 7 · see citing works

Shared genetic architecture and causal relationship between sleep behaviors and lifespan

Wu, Y., Zhang, C., Liu, X., Wang, L., Li, M., Li, Y., & Xiao, X. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02826-x · Cited by 7 · see citing works

The relationship between the morningness-eveningness questionnaire and incident cancer: A historical clinical cohort study

Kendzerska, T., Murray, B. J., Colelli, D. R., Cruz, G. R. D., Gershon, A. S., Povitz, M., Talarico, R., & Boulos, M. I. (2024) · Sleep Medicine · doi:10.1016/j.sleep.2024.03.020 · Cited by 7 · see citing works

Human genetic variation determines 24-hour rhythmic gene expression and disease risk

Chen, Y., Liu, P., Sabo, A., & Guan, D. (2025) · Nature Communications · doi:10.1038/s41467-025-59524-5 · Cited by 7 · see citing works

A conserved role for ALG10/ALG10B and the N -glycosylation pathway in the sleep-epilepsy axisPreprint

Gill, S., Mandigo, T. R., Elmalı, A. D., Leger, B. S., Yang, B., Tran, S., Laosuntisuk, K., Lane, J. M., Bannister, D., Aonbangkhen, C., et al. (2024) · medRxiv · doi:10.1101/2024.12.11.24318624 · Cited by 7 · see citing works

Scientific parallels of sleep physiology in the Qur’anic narrative of the Companions of the Cave “the Cave Sleepers”

Dhahbi, W., BaHammam, A. S., Omri, A. E., Dergaa, I., Souissi, A., Dhahbi, A. B., & Saad, H. B. (2025) · Sleep And Breathing · doi:10.1007/s11325-025-03377-1 · Cited by 6 · see citing works

Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules beat-Ia/CADM2

Mace, K. D., Zimmerman, A. J., Chesi, A., Doldur-Balli, F., Kim, H., Valle, E. A. D., Rosa, J. B., Pack, A. I., Grant, S. F. A., & Kayser, M. S. (2026) · Nature Communications · doi:10.1038/s41467-026-68343-1 · Cited by 6 · see citing works

Sleep disturbances are associated with pain intensity and pain‐related functional interference in patients experiencing orofacial pain

Ravindranath, P. T., Smith, J. G., Niloofar, R. N., Ebelthite, C., & Renton, T. F. (2023) · Journal of Oral Rehabilitation · doi:10.1111/joor.13521 · Cited by 6 · see citing works

G Protein-Coupled Receptors and the Rise of Type 2 Diabetes in Children

Dallatana, A., Cremonesi, L., Trombetta, M., Fracasso, G., Nocini, R., Giacomello, L., & Innamorati, G. (2023) · Biomedicines · doi:10.3390/biomedicines11061576 · Cited by 6 · see citing works

Identification of six genes associated with COVID-19-related circadian rhythm dysfunction by integrated bioinformatic analysis

Xu, Y., Zhang, M., Wang, G., & Yang, J. (2023) · Functional & Integrative Genomics · doi:10.1007/s10142-023-01198-7 · Cited by 6 · see citing works

Hematopoietic Stem Cells as an Integrative Hub Linking Lifestyle to Cardiovascular Health

Chen, X., Liu, C., Wang, J., & Du, C. (2024) · Cells · doi:10.3390/cells13080712 · Cited by 6 · see citing works

Maternal high fat diet induces circadian clock-independent endocrine alterations impacting the metabolism of the offspring

Ding, L., Weger, B. D., Liu, J. Y., Zhou, L., Lim, Y., Wang, D., Xie, Z., Liu, J., Ren, J., Zheng, J., et al. (2024) · iScience · doi:10.1016/j.isci.2024.110343 · Cited by 6 · see citing works

Mendelian randomization in SLEEP: avoiding pitfalls with MR-SLEEP guidelines

Evans, D. S., Pack, A. I., Gozal, D., & Stone, K. L. (2025) · SLEEP · doi:10.1093/sleep/zsaf054 · Cited by 6 · see citing works

Work is associated with a more robust rest-activity rhythm and high-intensity physical activity among older adults

Lee, P.-S., Liu, Y.-L., Chen, Y., & Cheng, W. (2025) · Aging Clinical and Experimental Research · doi:10.1007/s40520-025-03083-8 · Cited by 6 · see citing works

Gut microbiota, circadian rhythms and their interactions: implications for the pathogenesis and treatment of depression

Du, D., Yuan, Y., Guan, X., Xie, Q., Sun, X., & Dong, Z. (2025) · Annals of Medicine · doi:10.1080/07853890.2025.2561222 · Cited by 6 · see citing works

The dual role of autophagy in cartilage degradation: from mechanisms to targeted therapeutics

Mei, J., Zhang, S., Cui, X., Yang, R., Ke, J., Cui, L., Tan, L., Zhu, S., & Ma, Y. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1737547 · Cited by 5 · see citing works

Bidirectional effects of physical activity and sleep on health: evidence and future directions

Clemente‐Suárez, V. J., Redondo-Flórez, L., Beltrán-Velasco, A. I., Ramos‐Campo, D. J., Ruisoto, P., Sepulveda, R. A. Y., Martín-Rodríguez, A., & Tornero-Aguilera, J. F. (2026) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2026.1739588 · Cited by 5 · see citing works

Siesta behavior and genetics interact to influence obesity risk

Rodríguez‐Martín, M., Salmerón, D., Dashti, H. S., Cascales, A. I., Alonso, A. A., Scheer, F. A. J. L., Saxena, R., & Garaulet, M. (2024) · Obesity · doi:10.1002/oby.24173 · Cited by 5 · see citing works

Circadian Rhythms and Lung Cancer in the Context of Aging: A Review of Current Evidence

Xu, W., Li, L., Cao, Z., Ye, J., & Gu, X. (2025) · Aging and Disease · doi:10.14336/ad.2024.1188 · Cited by 5 · see citing works

Association between accelerometer-measured irregular sleep duration and longitudinal changes in body mass index in older adults

Kianersi, S., Potts, K. S., Wang, H., Sofer, T., Noordam, R., Rutter, M. K., Redline, S. S., & Huang, T. (2025) · International Journal of Obesity · doi:10.1038/s41366-025-01768-8 · Cited by 5 · see citing works

Chronotherapy and intervertebral disc degeneration: understanding the role of circadian rhythm in degenerative processes

Zhang, C., Zhang, R., Zhao, G., Wu, Z., Song, W., Ran, R., Zhou, K., & Zhang, H. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1586193 · Cited by 5 · see citing works

Late bedtime was associated with increased androgen and reduced lean mass in women with polycystic ovary syndrome: a cross-sectional study

Zhang, Y., Zhang, M., Cai, M., Shao, X., Dilimulati, D., Lu, J., Zhu, C., Chen, H., Li, C., Qu, S., et al. (2025) · Journal of Ovarian Research · doi:10.1186/s13048-025-01730-2 · Cited by 5 · see citing works

Association between sleep traits and sarcopenia‐related traits: A two‐sample bidirectional Mendelian randomization study

Ye, R., Pan, J., Hu, X., Xie, J., & Li, P. (2024) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.14877 · Cited by 5 · see citing works

Genetic basis of human circadian rhythm disorders

Jones, C. R., Huang, A. L., Ptáček, L. J., & Fu, Y. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.07.012 · Cited by 79 · see citing works

The genetics of circadian rhythms, sleep and health

Jagannath, A., Taylor, L., Wakaf, Z., Vasudevan, S. R., & Foster, F. (2017) · Human Molecular Genetics · doi:10.1093/hmg/ddx240 · Cited by 258 · see citing works

The genetics of mammalian circadian order and disorder: implications for physiology and disease

Takahashi, J. S., Hong, H.-K., Ko, C. H., & McDearmon, E. L. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2430 · Cited by 1,611 · see citing works

Circadian Rhythm Sleep Disorders: Genetics, Mechanisms, and Adverse Effects on Health

Liu, C., Tang, X., Gong, Z., Wang, Z., Hou, Q., & Lu, R. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.875342 · Cited by 39 · see citing works

Sleep Disturbances Linked to Genetic Disorders

Tedjasukmana, R. (2022) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2021.10.005 · Cited by 5 · see citing works