Most cited biochemistry, genetics and molecular biology papers
- Verified
Deep phenotyping of 89 xeroderma pigmentosum patients reveals unexpected heterogeneity dependent on the precise molecular defect
Fassihi, H., Sethi, M., Fawcett, H., Wing, J., Chandler, N., Mohammed, S., Craythorne, E., Morley, A. M. S., Lim, R., Turner, S., et al. (2016) · Proceedings of the National Academy of Sciences
DNA Repair MechanismsGenetic and rare skin diseases.
Cited by 199
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In Silico Modeling of PROTAC-Mediated Ternary Complexes: Validation and Application
Drummond, M. L., & Williams, C. I. (2019) · Journal of Chemical Information and Modeling
Protein Degradation and InhibitorsComputational Drug Discovery Methods
Cited by 199
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MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells
Kuang, F., Liu, J., Xie, Y., Tang, D., & Kang, R. (2021) · Cell Chemical Biology
Ferroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stress
Cited by 199
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moco: Fast Motion Correction for Calcium Imaging
Dubbs, A., Guevara, J., & Yuste, R. (2016) · Frontiers in Neuroinformatics
Cell Image Analysis TechniquesAdvanced Fluorescence Microscopy Techniques
Cited by 199
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The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously
Herman, M. A., Vassilieva, L. L., Horvitz, H. R., Shaw, J. E., & Herman, R. K. (1995) · Cell
Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer
Cited by 199
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MOTS-c Is an Exercise-Induced Mitochondrial-Encoded Regulator of Age-Dependent Physical Decline and Muscle Homeostasis
Reynolds, J. C., Lai, R. W., Woodhead, J. S. T., Joly, J. H., Mitchell, C. J., Cameron-Smith, D., Lu, R., Cohen, P., Graham, N. A., Benayoun, B. A., et al. (2021) · Nature Communications
Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms
Cited by 199
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PPARα and dyslipidemia
DUVAL, C., MULLER, M., & KERSTEN, S. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Peroxisome Proliferator-Activated ReceptorsCholesterol and Lipid Metabolism
Cited by 199
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Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21
Abels, E. R., Maas, S. L. N., Nieland, L., Wei, Z., Cheah, P. S., Tai, E., Kolsteeg, C.-J., Dusoswa, S. A., Ting, D. T., Hickman, S., et al. (2019) · Cell Reports
Extracellular vesicles in diseaseMicroRNA in disease regulation
Cited by 199
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Respiration-dependent H2O2 removal in brain mitochondria via the thioredoxin/peroxiredoxin system
Drechsel, D. A., & Patel, M. (2010) · Journal of Biological Chemistry
Redox biology and oxidative stressMitochondrial Function and Pathology
Cited by 199
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Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets
Dayeh, T. A., Olsson, A. H., Volkov, P., Almgren, P., Rönn, T., & Ling, C. (2013) · Diabetologia
Epigenetics and DNA MethylationGenetic Associations and Epidemiology
Cited by 199
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Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila
Slack, C., Foley, A., & Partridge, L. (2012) · PLoS ONE
Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer
Cited by 199
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Excitonic effects from geometric order and disorder explain broadband optical absorption in eumelanin
Chen, C.-T., Chuang, C., Cao, J., Ball, V., Ruch, D., & Buehler, M. J. (2014) · Nature Communications
melanin and skin pigmentationSpectroscopy and Quantum Chemical Studies
Cited by 199
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Induction of cellular senescence by insulin-like growth factor binding protein-5 through a p53-dependent mechanism
Kim, K. S., Seu, Y. B., Baek, S.-H., Kim, M. J., Kim, K. J., Kim, J. H., & Kim, J.-R. (2007) · Molecular Biology of the Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 199
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Single-cell atlas of healthy human blood unveils age-related loss of NKG2C+GZMB−CD8+ memory T cells and accumulation of type 2 memory T cells
Terekhova, M., Swain, A., Bohacova, P., Aladyeva, E., Arthur, L., Laha, A., Mogilenko, D. A., Burdess, S., Sukhov, V., Kleverov, D., et al. (2023) · Immunity
Single-cell and spatial transcriptomicsT-cell and B-cell Immunology
Cited by 199
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Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence.
Murano, S., Thweatt, R., Shmookler Reis, R. J., Jones, R. A., Moerman, E. J., & Goldstein, S. (1991) · Molecular and Cellular Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 199
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Induction of Apoptosis by Double-Stranded-RNA-Dependent Protein Kinase (PKR) Involves the α Subunit of Eukaryotic Translation Initiation Factor 2 and NF-κB
Gil, J., Alcamí, J., & Esteban, M. (1999) · Molecular and Cellular Biology
Endoplasmic Reticulum Stress and DiseaseNF-κB Signaling Pathways
Cited by 199
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Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study
Prins, B. P., Abbasi, A., Wong, A., Vaez, A., Nolte, I., Franceschini, N., Stuart, P. E., Guterriez Achury, J., Mistry, V., Bradfield, J. P., et al. (2016) · PLOS Medicine
Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases
Cited by 199
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Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli
Cronk, J. C., Derecki, N. C., Ji, E., Xu, Y., Lampano, A. E., Smirnov, I., Baker, W., Norris, G. T., Marin, I., Coddington, N., et al. (2015) · Immunity
Genetics and Neurodevelopmental DisordersNeuroinflammation and Neurodegeneration Mechanisms
Cited by 199
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Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells
Hu, G., Cui, K., Fang, D., Hirose, S., Wang, X., Wangsa, D., Jin, W., Ried, T., Liu, P., Zhu, J., et al. (2018) · Immunity
Genomics and Chromatin DynamicsT-cell and B-cell Immunology
Cited by 199
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Novel Allosteric Modulators of G Protein-coupled Receptors
Gentry, P. R., Sexton, P. M., & Christopoulos, A. (2015) · Journal of Biological Chemistry
Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research
Cited by 199
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Pseudomonas aeruginosa and their small diffusible extracellular molecules inhibit Aspergillus fumigatus biofilm formation: Pseudomonas inhibits Aspergillus biofilms
Mowat, E., Rajendran, R., Williams, C., McCulloch, E., Jones, B., Lang, S., & Ramage, G. (2010) · FEMS Microbiology Letters
Bacterial biofilms and quorum sensingAntifungal resistance and susceptibility
Cited by 199
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The Multifactorial Model of Disease Transmission: I. Description of the Model and its use in Psychiatry
Reich, T., Cloninger, C. R., & Guze, S. B. (1975) · British Journal of Psychiatry
Genetic Associations and EpidemiologyMental Health Research Topics
Cited by 199
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Diacylglycerol-evoked activation of PKC and PKD isoforms in regulation of glucose and lipid metabolism: a review
Kolczynska, K., Loza-Valdes, A., Hawro, I., & Sumara, G. (2020) · Lipids in Health and Disease
Protein Kinase Regulation and GTPase SignalingMetabolism, Diabetes, and Cancer
Cited by 199
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Effects of elevated pCO2 and osmolality on growth of CHO cells and production of antibody-fusion protein B1: A case study
Zhu, M. M., Goyal, A., Rank, D. L., Gupta, S. K., Boom, T. V., & Lee, S. S. (2008) · Biotechnology Progress
Viral Infectious Diseases and Gene Expression in InsectsFluid Dynamics and Mixing
Cited by 199
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