Most cited biochemistry, genetics and molecular biology papers
- Verified
Loss of chondroitin 6- O -sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement
Thiele, H., Sakano, M., Kitagawa, H., Sugahara, K., Rajab, A., Höhne, W., Ritter, H., Leschik, G., Nürnberg, P., & Mundlos, S. (2004) · Proceedings of the National Academy of Sciences
Proteoglycans and glycosaminoglycans researchConnective tissue disorders research
Cited by 190
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AI revolutions in biology: The joys and perils of AlphaFold
Perrakis, A., & Sixma, T. K. (2021) · The EMBO Reports
Protein Structure and DynamicsMachine Learning in Bioinformatics
Cited by 190
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Large‐scale molecular characterization of adeno‐associated virus vector integration in mouse liver
Nakai, H., Wu, X., Fuess, S., Storm, T. A., Munroe, D., Montini, E., Burgess, S. M., Grompe, M., & Kay, M. A. (2005) · Journal of Virology
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 190
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Aromatase: biologic relevance of tissue-specific expression
Simpson, E. R. (2004) · Seminars in Reproductive Medicine
Estrogen and related hormone effectsPhytoestrogen effects and research
Cited by 190
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Pregnancy rate and outcome in Swedish women with Turner syndrome
Bryman, I., Sylvén, L., Berntorp, K., Innala, E., Bergström, I., Hanson, C., Oxholm, M., & Landin-Wilhelmsen, K. (2011) · Fertility and Sterility
Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesSexual Differentiation and Disorders
Cited by 190
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Essential metabolism for a minimal cell
Breuer, M., Earnest, E. E., Merryman, C., Wise, K. S., Sun, L., Lynott, M. R., Hutchison, C. A., Smith, H. O., Lapek, J. D., Gonzalez, D. J., et al. (2019) · eLife
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 190
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A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Fang, L., Zhu, Q., Neuenschwander, M., Specker, E., Wulf-Goldenberg, A., Weis, W. I., von Kries, J. P., & Birchmeier, W. (2016) · Cancer Research
Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis
Cited by 190
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Age-related sperm DNA methylation changes are transmitted to offspring and associated with abnormal behavior and dysregulated gene expression
Milekic, M. H., Xin, Y., O’Donnell, A., Kumar, K. K., Bradley-Moore, M., Malaspina, D., Moore, H., Brunner, D., Ge, Y., Edwards, J., et al. (2015) · Molecular Psychiatry
Epigenetics and DNA MethylationSperm and Testicular Function
Cited by 190
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Cross-talk between JNK/SAPK and ERK/MAPK Pathways
Shen, Y. H., Godlewski, J., Zhu, J., Sathyanarayana, P., Leaner, V., Birrer, M. J., Rana, A., & Tzivion, G. (2003) · Journal of Biological Chemistry
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 190
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Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders
Yang, J., Li, Y., Aguilar, A., Liu, Z., Yang, C.-Y., & Wang, S. (2019) · Journal of Medicinal Chemistry
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 190
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Inferring population size history from large samples of genome-wide molecular data - an approximate Bayesian computation approach
Boitard, S., Rodríguez, W., Jay, F., Mona, S., & Austerlitz, F. (2016) · PLoS Genetics
Genetic diversity and population structureForensic and Genetic Research
Cited by 190
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Hippo pathway coactivators Yap and Taz are required to coordinate mammalian liver regeneration
Lu, L., Finegold, M. J., & Johnson, R. L. (2018) · Experimental & Molecular Medicine
Hippo pathway signaling and YAP/TAZLiver physiology and pathology
Cited by 190
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SHP2 inhibition triggers anti-tumor immunity and synergizes with PD-1 blockade
Zhao, M., Guo, W., Wu, Y., Yang, C., Zhong, L., Deng, G., Zhu, Y., Liu, W., Gu, Y., Lu, Y., et al. (2019) · Acta Pharmaceutica Sinica B
Protein Tyrosine PhosphatasesCancer Immunotherapy and Biomarkers
Cited by 190
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Exploiting the bootstrap method for quantifying parameter confidence intervals in dynamical systems
Joshi, M., Seidel-Morgenstern, A., & Kremling, A. (2006) · Metabolic Engineering
Gene Regulatory Network AnalysisControl Systems and Identification
Cited by 190
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TNF signaling and macrophages govern fin regeneration in zebrafish larvae
Nguyen-Chi, M., Laplace-Builhé, B., Travnickova, J., Luz-Crawford, P., Tejedor, G., Lutfalla, G., Kissa, K., Jorgensen, C., & Djouad, F. (2017) · Cell Death & Disease
Zebrafish Biomedical Research ApplicationsPlanarian Biology and Electrostimulation
Cited by 190
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Epigenetic effects of metformin: from molecular mechanisms to clinical implications
Bridgeman, S. C., Ellison, G. C., Melton, P. E., Newsholme, P., & Mamotte, C. D. S. (2018) · Diabetes, Obesity and Metabolism
Metabolism, Diabetes, and CancerEpigenetics and DNA Methylation
Cited by 190
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Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndrome –Mecp2 gene dosage effects and BDNF expression
Kondo, M., Gray, L. J., Pelka, G. J., Christodoulou, J., Tam, P. P. L., & Hannan, A. J. (2008) · European Journal of Neuroscience
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 190
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Two-Dimensional Fluorescence Spectroscopy: A New Tool for On-Line Bioprocess Monitoring
Marose, S., Lindemann, C., & Scheper, T. (1998) · Biotechnology Progress
Spectroscopy Techniques in Biomedical and Chemical ResearchWater Quality Monitoring and Analysis
Cited by 190
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In vivo uptake of chylomicron [3H]retinyl ester by rat liver: evidence for retinol transfer from parenchymal to nonparenchymal cells.
Blomhoff, R., Helgerud, P., Rasmussen, M., Berg, T., & Norum, K. R. (1982) · Proceedings of the National Academy of Sciences
Retinoids in leukemia and cellular processesCholesterol and Lipid Metabolism
Cited by 190
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Structural and biological aspects of carotenoid cleavage
Kloer, D. P., & Schulz, G. E. (2006) · Cellular and Molecular Life Sciences
Retinoids in leukemia and cellular processesMetal-Catalyzed Oxygenation Mechanisms
Cited by 190
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A two-step model for senescence triggered by a single critically short telomere
Abdallah, P., Luciano, P., Runge, K. W., Lisby, M., Géli, V., Gilson, E., & Teixeira, M. T. (2009) · Nature Cell Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 190
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X-linked adrenoleukodystrophy: Genes, mutations, and phenotypes
Smith, K. D., Kemp, S., Braiterman, L. T., Lu, J.-F., Wei, H.-M., Geraghty, M., Stetten, G., Bergin, J. S., Pevsner, J., & Watkins, P. A. (1999) · Neurochemical Research
Metabolism and Genetic DisordersLysosomal Storage Disorders Research
Cited by 190
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Mitochondrial genes are altered in blood early in Alzheimer's disease
Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., et al. (2017) · Neurobiology of Aging
Mitochondrial Function and PathologyAlzheimer's disease research and treatments
Cited by 190
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Ras/Mitogen-Activated Protein Kinase Signaling Activates Ets-1 and Ets-2 by CBP/p300 Recruitment
Foulds, C. E., Nelson, M. L., Blaszczak, A. G., & Graves, B. J. (2004) · Molecular and Cellular Biology
Protein Kinase Regulation and GTPase SignalingGenomics and Chromatin Dynamics
Cited by 190
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