Most cited biochemistry, genetics and molecular biology papers
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Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation
Sato, A., Kono, T., Nakada, K., Ishikawa, K., Inoue, S.-I., Yonekawa, H., & Hayashi, J.-I. (2005) · Proceedings of the National Academy of Sciences
Mitochondrial Function and PathologyAnimal Genetics and Reproduction
Cited by 171
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Loss of microbicidal activity and increased formation of biofilm due to decreased lactoferrin activity in patients with cystic fibrosis
Rogan, M. P., Taggart, C. C., Greene, C. M., Murphy, P. G., O’Neill, S. J., & McElvaney, N. G. (2004) · The Journal of Infectious Diseases
Bacterial biofilms and quorum sensingCystic Fibrosis Research Advances
Cited by 171
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Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice
Kucerova, L., Matuskova, M., Pastorakova, A., Tyciakova, S., Jakubikova, J., Bohovic, R., Altanerova, V., & Altaner, C. (2008) · The Journal of Gene Medicine
Bacterial Cancer TherapyMesenchymal stem cell research
Cited by 171
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Evaluating and enhancing target specificity of gene-editing nucleases and deaminases
Kim, D., Luk, K., Wolfe, S. A., & Kim, J.-S. (2019) · Annual Review of Biochemistry
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 171
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The Ubiquitin–Proteasome System in Regulation of the Skeletal Muscle Homeostasis and Atrophy: From Basic Science to Disorders
Kitajima, Y., Yoshioka, K., & Suzuki, N. (2020) · The Journal of Physiological Sciences
Muscle Physiology and DisordersUbiquitin and proteasome pathways
Cited by 171
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Structure of the immature retroviral capsid at 8 Å resolution by cryo-electron microscopy
Bharat, T. A. M., Davey, N. E., Ulbrich, P., Riches, J. D., de Marco, A., Rumlova, M., Sachse, C., Ruml, T., & Briggs, J. A. G. (2012) · Nature
Advanced Electron Microscopy Techniques and ApplicationsHIV Research and Treatment
Cited by 171
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miR-155: An Important Role in Inflammation Response
Hu, J., Huang, S., Liu, X., Zhang, Y., Wei, S., & Hu, X. (2022) · Journal of Immunology Research
MicroRNA in disease regulationImmune Response and Inflammation
Cited by 171
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Mesenchymal Stem Cells in Cancer: Tumor-Associated Fibroblasts and Cell-Based Delivery Vehicles
Hall, B., Dembinski, J., Sasser, A., Studeny, M., Andreeff, M., & Marini, F. (2007) · International Journal of Hematology
Mesenchymal stem cell researchCancer Cells and Metastasis
Cited by 171
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Studies on the Respiratory Chain-linked Reduced Nicotinamide Adenine Dinucleotide Dehydrogenase
Palmer, G., Horgan, D. J., Tisdale, H., Singer, T. P., & Beinert, H. (1968) · Journal of Biological Chemistry
Mitochondrial Function and PathologyEnzyme Structure and Function
Cited by 171
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Trimethylamine N‐oxide: breathe new life
Subramaniam, S., & Fletcher, C. (2018) · British Journal of Pharmacology
Gut microbiota and healthPolyamine Metabolism and Applications
Cited by 171
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Keap Calm, and Carry on Covalently
Wilson, A. J., Kerns, J. K., Callahan, J. F., & Moody, C. J. (2013) · Journal of Medicinal Chemistry
Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress
Cited by 171
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Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species
Patten, D. A., Lafleur, V. N., Robitaille, G. A., Chan, D. A., Giaccia, A. J., & Richard, D. E. (2010) · Molecular Biology of the Cell
Cancer, Hypoxia, and MetabolismNitric Oxide and Endothelin Effects
Cited by 171
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Directed evolution of adeno-associated virus for efficient gene delivery to microglia
Lin, R., Zhou, Y., Yan, T., Wang, R., Li, H., Wu, Z., Zhang, X., Zhou, X., Zhao, F., Zhang, L., et al. (2022) · Nature Methods
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 171
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Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition
Rapisarda, A., Hollingshead, M., Uranchimeg, B., Bonomi, C. A., Borgel, S. D., Carter, J. P., Gehrs, B., Raffeld, M., Kinders, R. J., Parchment, R., et al. (2009) · Molecular Cancer Therapeutics
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 171
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Targeting telomerase for cancer therapeutics
Shay, J. W., & Keith, W. N. (2008) · British Journal of Cancer
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 171
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The glucose-6 phosphatase gene is expressed in human and rat small intestine: Regulation of expression in fasted and diabetic rats
Rajas, F., Bruni, N., Montano, S., Zitoun, C., & Mithieux, G. (1999) · Gastroenterology
Glycogen Storage Diseases and MyoclonusMetabolism, Diabetes, and Cancer
Cited by 171
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The interplay between apoptosis and cellular senescence: Bcl-2 family proteins as targets for cancer therapy
Basu, A. (2022) · Pharmacology & Therapeutics
Cell death mechanisms and regulationTelomeres, Telomerase, and Senescence
Cited by 171
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Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model
Xu, X., Sun, Y., Cen, X., Shan, B., Zhao, Q., Xie, T., Wang, Z., Hou, T., Xue, Y., Zhang, M., et al. (2021) · Protein & Cell
Autophagy in Disease and TherapyAlzheimer's disease research and treatments
Cited by 171
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Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse
Swindell, W. R. (2009) · BMC Genomics
Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine
Cited by 171
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Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment
Fan, T., Sun, G., Sun, X., Zhao, L., Zhong, R., & Peng, Y. (2019) · Cancers
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 171
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Protein sequence design with a learned potential
Anand, N., Eguchi, R., Mathews, I. I., Perez, C. P., Derry, A., Altman, R. B., & Huang, P.-S. (2022) · Nature Communications
Protein Structure and DynamicsMachine Learning in Bioinformatics
Cited by 171
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Movement of accessible plasma membrane cholesterol by the GRAMD1 lipid transfer protein complex
Naito, T., Ercan, B., Krshnan, L., Triebl, A., Koh, D. H. Z., Wei, F.-Y., Tomizawa, K., Torta, F. T., Wenk, M. R., & Saheki, Y. (2019) · eLife
Cholesterol and Lipid MetabolismLipid Membrane Structure and Behavior
Cited by 171
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Studies on mammalian mutants defective in rejoining double-strand breaks in DNA
Jeggo, P. A. (1990) · Mutation Research/Reviews in Genetic Toxicology
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 171
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Intramyocellular lipid and impaired myofiber contraction in normal weight and obese older adults
Choi, S. J., Files, D. C., Zhang, T., Wang, Z.-M., Messi, M. L., Gregory, H., Stone, J., Lyles, M. F., Dhar, S., Marsh, A. P., et al. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 171
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