Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

Leone, R. D., Zhao, L., Englert, J. M., Sun, I.-M., Oh, M.-H., Sun, I.-H., Arwood, M. L., Bettencourt, I. A., Patel, C. H., Wen, J., et al. (2019) · Science

Cancer, Hypoxia, and MetabolismCancer Immunotherapy and Biomarkers

Cited by 1,169

Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis

Olichon, A., Baricault, L., Gas, N., Guillou, E., Valette, A., Belenguer, P., & Lenaers, G. (2003) · Journal of Biological Chemistry

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 1,168

Cardioprotection and lifespan extension by the natural polyamine spermidine

Eisenberg, T., Abdellatif, M., Schroeder, S., Primessnig, U., Stekovic, S., Pendl, T., Harger, A., Schipke, J., Zimmermann, A., Schmidt, A., et al. (2016) · Nature Medicine

Polyamine Metabolism and ApplicationsGenetics, Aging, and Longevity in Model Organisms

Cited by 1,168

Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis

Marzo, I., Brenner, C., Zamzami, N., Jürgensmeier, J. M., Susin, S. A., Vieira, H. L. A., Prévost, M.-C., Xie, Z., Matsuyama, S., Reed, J. C., et al. (1998) · Science

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 1,168

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

Chen, J. S., Dagdas, Y. S., Kleinstiver, B. P., Welch, M. M., Sousa, A. A., Harrington, L. B., Sternberg, S. H., Joung, J. K., Yildiz, A., & Doudna, J. A. (2017) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,168

A telomerase component is defective in the human disease dyskeratosis congenita

Mitchell, J. R., Wood, E., & Collins, K. (1999) · Nature

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 1,168

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

Chao, H.-T., Chen, H., Samaco, R. C., Xue, M., Chahrour, M., Yoo, J., Neul, J. L., Gong, S., Lu, H.-C., Heintz, N., et al. (2010) · Nature

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 1,168

Function and biogenesis of iron-sulphur proteins

Lill, R. (2009) · Nature

Metalloenzymes and iron-sulfur proteinsEnzyme Structure and Function

Cited by 1,167

Structural basis of water-specific transport through the AQP1 water channel

Sui, H., Han, B.-G., Lee, J. K., Walian, P., & Jap, B. K. (2001) · Nature

Ion Transport and Channel RegulationNanopore and Nanochannel Transport Studies

Cited by 1,166

Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals

Djouad, F., Plence, P., Bony, C., Tropel, P., Apparailly, F., Sany, J., Noël, D., & Jorgensen, C. (2003) · Blood

Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation

Cited by 1,166

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

Ma, Y., Pannicke, U., Schwarz, K., & Lieber, M. R. (2002) · Cell

DNA Repair MechanismsCRISPR and Genetic Engineering

Cited by 1,166

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

Chavrier, P., Parton, R. G., Hauri, H. P., Simons, K., & Zerial, M. (1990) · Cell

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 1,166

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

Zamzami, N., Marchetti, P., Castedo, M., Zanin, C., Vayssière, J. L., Petit, P. X., & Kroemer, G. (1995) · The Journal of experimental medicine

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 1,166

In vivo enhancer analysis of human conserved non-coding sequences

Pennacchio, L. A., Ahituv, N., Moses, A. M., Prabhakar, S., Nobrega, M. A., Shoukry, M., Minovitsky, S., Dubchak, I., Holt, A., Lewis, K. D., et al. (2006) · Nature

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 1,165

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

Tollervey, J. R., Curk, T., Rogelj, B., Briese, M., Cereda, M., Kayikci, M., König, J., Hortobágyi, T., Nishimura, A. L., Župunski, V., et al. (2011) · Nature Neuroscience

RNA Research and SplicingAmyotrophic Lateral Sclerosis Research

Cited by 1,165

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

Tang, Y., Wu, X., Lei, W., Pang, L., Wan, C., Shi, Z., Zhao, L., Nagy, T. R., Peng, X., Hu, J., et al. (2009) · Nature Medicine

Bone Metabolism and DiseasesTGF-β signaling in diseases

Cited by 1,165

Chronic kidney disease alters intestinal microbial flora

Vaziri, N. D., Wong, J., Pahl, M., Piceno, Y. M., Yuan, J., DeSantis, T. Z., Ni, Z., Nguyen, T.-H., & Andersen, G. L. (2013) · Kidney International

Gut microbiota and healthDialysis and Renal Disease Management

Cited by 1,164

A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly

Lettice, L. A. (2003) · Human Molecular Genetics

Congenital limb and hand anomaliesGenomics and Chromatin Dynamics

Cited by 1,164

Receptor Specificity of the Fibroblast Growth Factor Family

Zhang, X., Ibrahimi, O. A., Olsen, S. K., Umemori, H., Mohammadi, M., & Ornitz, D. M. (2006) · Journal of Biological Chemistry

Fibroblast Growth Factor ResearchConnective Tissue Growth Factor Research

Cited by 1,164

Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors

Konermann, S., Lotfy, P., Brideau, N. J., Oki, J., Shokhirev, M. N., & Hsu, P. D. (2018) · Cell

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,164

The Protein Folding Problem

Dill, K. A., Ozkan, S. B., Shell, M. S., & Weikl, T. R. (2008) · Annual Review of Biophysics

Protein Structure and DynamicsRNA and protein synthesis mechanisms

Cited by 1,163

Protein Data Bank: the single global archive for 3D macromolecular structure data

wwPDB consortium, Burley, S. K., Berman, H. M., Bhikadiya, C., Bi, C., Chen, L., Costanzo, L. D., Christie, C., Duarte, J. M., Dutta, S., et al. (2019) · Nucleic Acids Research

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 1,163

Targeting RAS–ERK signalling in cancer: promises and challenges

Samatar, A. A., & Poulikakos, P. I. (2014) · Nature Reviews Drug Discovery

Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 1,163

Paired-End Mapping Reveals Extensive Structural Variation in the Human Genome

Korbel, J. O., Urban, A. E., Affourtit, J. P., Godwin, B., Grubert, F., Simons, J. F., Kim, P. M., Palejev, D., Carriero, N. J., Du, L., et al. (2007) · Science

Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms

Cited by 1,163