Most cited biochemistry, genetics and molecular biology papers
- Verified
Ultrasensitivity in the mitogen-activated protein kinase cascade.
Huang, C. Y., & Ferrell, J. E. (1996) · Proceedings of the National Academy of Sciences
Gene Regulatory Network AnalysisProtein Kinase Regulation and GTPase Signaling
Cited by 1,186
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Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression
Nelson, D. E., Ihekwaba, A. E. C., Elliott, M., Johnson, J. R., Gibney, C. A., Foreman, B. E., Nelson, G., See, V., Horton, C. A., Spiller, D. G., et al. (2004) · Science
NF-κB Signaling PathwaysGene Regulatory Network Analysis
Cited by 1,186
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Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
Yadav, M., Jhunjhunwala, S., Phung, Q. T., Lupardus, P., Tanguay, J., Bumbaca, S., Franci, C., Cheung, T. K., Fritsche, J., Weinschenk, T., et al. (2014) · Nature
vaccines and immunoinformatics approachesCancer Immunotherapy and Biomarkers
Cited by 1,186
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Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of Rapamycin
Hudson, C. C., Liu, M., Chiang, G. G., Otterness, D. M., Loomis, D. C., Kaper, F., Giaccia, A. J., & Abraham, R. T. (2002) · Molecular and Cellular Biology
Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer
Cited by 1,186
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Senescence is a developmental mechanism that contributes to embryonic growth and patterning
Storer, M., Mas, A., Robert-Moreno, A., Pecoraro, M., Ortells, M. C., Di Giacomo, V., Yosef, R., Pilpel, N., Krizhanovsky, V., Sharpe, J., et al. (2013) · Cell
Telomeres, Telomerase, and SenescenceDevelopmental Biology and Gene Regulation
Cited by 1,186
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Exosomes: key players in cancer and potential therapeutic strategy
Dai, J., Su, Y., Zhong, S., Cong, L., Liu, B., Yang, J., Tao, Y., He, Z., Chen, C., & Jiang, Y. (2020) · Signal Transduction and Targeted Therapy
Extracellular vesicles in diseaseMicroRNA in disease regulation
Cited by 1,186
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On the allelic spectrum of human disease
Reich, D. E., & Lander, E. S. (2001) · Trends in Genetics
Genetic Associations and EpidemiologyGenomics and Rare Diseases
Cited by 1,185
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BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly
Kuwana, T., Bouchier-Hayes, L., Chipuk, J. E., Bonzon, C., Sullivan, B. A., Green, D. R., & Newmeyer, D. D. (2005) · Molecular Cell
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 1,185
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The MAPK signalling pathways and colorectal cancer
Fang, J. Y., & Richardson, B. C. (2005) · The Lancet Oncology
Melanoma and MAPK PathwaysColorectal Cancer Treatments and Studies
Cited by 1,185
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Essential role for Nix in autophagic maturation of erythroid cells
Sandoval, H., Thiagarajan, P., Dasgupta, S. K., Schumacher, A., Prchal, J. T., Chen, M., & Wang, J. (2008) · Nature
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 1,185
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Delivering CRISPR: a review of the challenges and approaches
Lino, C. A., Harper, J. C., Carney, J. P., & Timlin, J. A. (2018) · Drug Delivery
CRISPR and Genetic EngineeringRNA Interference and Gene Delivery
Cited by 1,185
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ERK signalling: A master regulator of cell behaviour, life and fate
Lavoie, H., Gagnon, J., & Therrien, M. (2020) · Nature Reviews Molecular Cell Biology
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 1,185
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Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases
Nandi, A., Yan, L.-J., Jana, C. K., & Das, N. (2019) · Oxidative Medicine and Cellular Longevity
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 1,185
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Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
Dai, X.-M., Ryan, G. R., Hapel, A. J., Dominguez, M. G., Russell, R. G., Kapp, S., Sylvestre, V., & Stanley, E. R. (2002) · Blood
Bone Metabolism and DiseasesPhagocytosis and Immune Regulation
Cited by 1,184
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Glycan foraging in vivo by an intestine-adapted bacterial symbiont
Sonnenburg, J. L., Xu, J., Leip, D. D., Chen, C.-H., Westover, B. P., Weatherford, J., Buhler, J. D., & Gordon, J. I. (2005) · Science
Gut microbiota and healthMicrobial Metabolites in Food Biotechnology
Cited by 1,184
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Genome evolution and adaptation in a long-term experiment with Escherichia coli
Barrick, J. E., Yu, D. S., Yoon, S. H., Jeong, H., Oh, T. K., Schneider, D., Lenski, R. E., & Kim, J. F. (2009) · Nature
Evolution and Genetic DynamicsLanguage and cultural evolution
Cited by 1,184
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X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
Putnam, C. D., Hammel, M., Hura, G. L., & Tainer, J. A. (2007) · Quarterly Reviews of Biophysics
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 1,184
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Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
MetaHIT Consortium, Nielsen, H. B., Almeida, M., Juncker, A. S., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D. R., Gautier, L., Pedersen, A. G., et al. (2014) · Nature Biotechnology
Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology
Cited by 1,184
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Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT
Suez, J., Zmora, N., Zilberman-Schapira, G., Mor, U., Dori-Bachash, M., Bashiardes, S., Zur, M., Regev-Lehavi, D., Ben-Zeev Brik, R., Federici, S., et al. (2018) · Cell
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 1,184
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Gene therapy returns to centre stage
Naldini, L. (2015) · Nature
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 1,184
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Ubiquitin signalling in the NF-κB pathway
Chen, Z. J. (2005) · Nature Cell Biology
NF-κB Signaling PathwaysUbiquitin and proteasome pathways
Cited by 1,184
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Quantitative single-cell RNA-seq with unique molecular identifiers
Islam, S., Zeisel, A., Joost, S., La Manno, G., Zajac, P., Kasper, M., Lönnerberg, P., & Linnarsson, S. (2014) · Nature Methods
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,183
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Regulated transport of the glucose transporter GLUT4
Bryant, N. J., Govers, R., & James, D. E. (2002) · Nature Reviews Molecular Cell Biology
Metabolism, Diabetes, and CancerCellular transport and secretion
Cited by 1,183
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Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
Sharon, G., Cruz, N. J., Kang, D.-W., Gandal, M. J., Wang, B., Kim, Y.-M., Zink, E. M., Casey, C. P., Taylor, B. C., Lane, C. J., et al. (2019) · Cell
Gut microbiota and healthAutism Spectrum Disorder Research
Cited by 1,182
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