Most cited biochemistry, genetics and molecular biology papers
- Verified
Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition
Luan, D. D., Korman, M. H., Jakubczak, J. L., & Eickbush, T. H. (1993) · Cell
Chromosomal and Genetic VariationsGenomics and Chromatin Dynamics
Cited by 1,173
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Supporting aspartate biosynthesis is an essential function of respiration in proliferating cells
Sullivan, L. B., Gui, D. Y., Hosios, A. M., Bush, L. N., Freinkman, E., & Vander Heiden, M. G. (2015) · Cell
Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology
Cited by 1,173
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PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene.
Schoonjans, K., Peinado‐Onsurbe, J., Lefebvre, A. M., Heyman, R. A., Briggs, M., Deeb, S., Staels, B., & Auwerx, J. (1996) · The EMBO Journal
Peroxisome Proliferator-Activated ReceptorsLipid metabolism and disorders
Cited by 1,173
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The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus
Eizirik, D. L., Cardozo, A. K., & Cnop, M. (2008) · Endocrine Reviews
Endoplasmic Reticulum Stress and DiseasePancreatic function and diabetes
Cited by 1,173
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Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies
Winkler, A. M., Kochunov, P., Blangero, J., Almasy, L., Zilles, K., Fox, P. T., Duggirala, R., & Glahn, D. C. (2010) · NeuroImage
Genetic Associations and EpidemiologyAdvanced Neuroimaging Techniques and Applications
Cited by 1,172
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The key role of anaplerosis and cataplerosis for citric acid cycle function
Owen, O. E., Kalhan, S. C., & Hanson, R. W. (2002) · Journal of Biological Chemistry
Biochemical Acid Research StudiesMitochondrial Function and Pathology
Cited by 1,172
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Targeting KRAS mutant cancers with a covalent G12C-specific inhibitor
Janes, M. R., Zhang, J., Li, L.-S., Hansen, R., Peters, U., Guo, X., Chen, Y., Babbar, A., Firdaus, S. J., Darjania, L., et al. (2018) · Cell
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 1,172
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Chapter 11: Genome-wide association studies
Bush, W. S., & Moore, J. H. (2012) · PLoS Computational Biology
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,171
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A general two-metal-ion mechanism for catalytic RNA
Steitz, T. A., & Steitz, J. A. (1993) · Proceedings of the National Academy of Sciences
RNA and protein synthesis mechanismsPhysical Organic Chemistry and Reaction Kinetics
Cited by 1,171
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Organizational principles of 3D genome architecture
Rowley, M. J., & Corces, V. G. (2018) · Nature Reviews Genetics
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 1,171
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Bilateral Prophylactic Mastectomy Reduces Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group
Rebbeck, T. R., Friebel, T., Lynch, H. T., Neuhausen, S. L., van ’t Veer, L., Garber, J. E., Evans, G. R., Narod, S. A., Isaacs, C., Matloff, E., et al. (2004) · Journal of Clinical Oncology
BRCA gene mutations in cancerWomen's cancer prevention and management
Cited by 1,171
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Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications
Sato, T., & Clevers, H. (2013) · Science
Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis
Cited by 1,170
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The FoxO code
Calnan, D. R., & Brunet, A. (2008) · Oncogene
FOXO transcription factor regulationMetabolism, Diabetes, and Cancer
Cited by 1,170
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Living on a break: cellular senescence as a DNA-damage response
d'Adda di Fagagna, F. (2008) · Nature Reviews Cancer
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,170
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GABA-modulating bacteria of the human gut microbiota
Strandwitz, P., Kim, K. H., Terekhova, D., Liu, J. K., Sharma, A., Levering, J., McDonald, D., Dietrich, D., Ramadhar, T. R., Lekbua, A., et al. (2018) · Nature Microbiology
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 1,170
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Oxygen radicals and signaling
Finkel, T. (1998) · Current Opinion in Cell Biology
Redox biology and oxidative stressNitric Oxide and Endothelin Effects
Cited by 1,170
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Computational and analytical challenges in single-cell transcriptomics
Stegle, O., Teichmann, S. A., & Marioni, J. C. (2015) · Nature Reviews Genetics
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,170
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Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression
Gaur, T., Lengner, C. J., Hovhannisyan, H., Bhat, R. A., Bodine, P. V. N., Komm, B. S., Javed, A., van Wijnen, A. J., Stein, J. L., Stein, G. S., et al. (2005) · Journal of Biological Chemistry
Wnt/β-catenin signaling in development and cancerBone Metabolism and Diseases
Cited by 1,170
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PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
Chinetti, G., Lestavel, S., Bocher, V., Remaley, A. T., Neve, B., Torra, I. P., Teissier, E., Minnich, A., Jaye, M., Duverger, N., et al. (2001) · Nature Medicine
Cholesterol and Lipid MetabolismPeroxisome Proliferator-Activated Receptors
Cited by 1,170
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Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation
Winkler, F., Kozin, S. V., Tong, R. T., Chae, S.-S., Booth, M. F., Garkavtsev, I., Xu, L., Hicklin, D. J., Fukumura, D., di Tomaso, E., et al. (2004) · Cancer Cell
Angiogenesis and VEGF in CancerBarrier Structure and Function Studies
Cited by 1,170
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Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG
Parekh, R. B., Dwek, R. A., Sutton, B. J., Fernandes, D. L., Leung, A., Stanworth, D., Rademacher, T. W., Mizuochi, T., Taniguchi, T., Matsuta, K., et al. (1985) · Nature
Glycosylation and Glycoproteins ResearchRheumatoid Arthritis Research and Therapies
Cited by 1,170
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Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
Wang, H., Liao, H., Ochani, M., Justiniani, M., Lin, X., Yang, L., Al-Abed, Y., Wang, H., Metz, C., Miller, E. J., et al. (2004) · Nature Medicine
Advanced Glycation End Products researchSepsis Diagnosis and Treatment
Cited by 1,170
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MITF: master regulator of melanocyte development and melanoma oncogene
Levy, C., Khaled, M., & Fisher, D. E. (2006) · Trends in Molecular Medicine
Melanoma and MAPK Pathwaysmelanin and skin pigmentation
Cited by 1,169
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Molecular recognition of fatty acids by peroxisome proliferator-activated receptors
Xu, H. E., Lambert, M. H., Montana, V. G., Parks, D. J., Blanchard, S. G., Brown, P. J., Sternbach, D. D., Lehmann, J. M., Wisely, G. B., Willson, T. M., et al. (1999) · Molecular Cell
Peroxisome Proliferator-Activated ReceptorsProtein Structure and Dynamics
Cited by 1,169
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