Most cited biochemistry, genetics and molecular biology papers
- Verified
The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
Greider, C. W., & Blackburn, E. H. (1987) · Cell
Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry
Cited by 1,150
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Stress & the gut-brain axis: Regulation by the microbiome
Foster, J. A., Rinaman, L., & Cryan, J. F. (2017) · Neurobiology of Stress
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,150
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In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
Suzuki, K., Tsunekawa, Y., Hernandez-Benitez, R., Wu, J., Zhu, J., Kim, E. J., Hatanaka, F., Yamamoto, M., Araoka, T., Li, Z., et al. (2016) · Nature
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,150
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Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
Ward, I. M., & Chen, J. (2001) · Journal of Biological Chemistry
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 1,150
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Interaction of antibiotics with functional sites in 16S ribosomal RNA
Moazed, D., & Noller, H. F. (1987) · Nature
RNA and protein synthesis mechanismsRNA modifications and cancer
Cited by 1,150
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High-definition spatial transcriptomics for in situ tissue profiling
Vickovic, S., Eraslan, G., Salmén, F., Klughammer, J., Stenbeck, L., Schapiro, D., Äijö, T., Bonneau, R., Bergenstråhle, L., Navarro, J. F., et al. (2019) · Nature Methods
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 1,150
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Role of advanced glycation end products in cellular signaling
Ott, C., Jacobs, K., Haucke, E., Navarrete Santos, A., Grune, T., & Simm, A. (2014) · Redox Biology
Advanced Glycation End Products researchPotato Plant Research
Cited by 1,150
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Cellular senescence: the good, the bad and the unknown
Huang, W., Hickson, L. J., Eirin, A., Kirkland, J. L., & Lerman, L. O. (2022) · Nature Reviews Nephrology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,150
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Biallelic Inactivation of BRCA2 in Fanconi Anemia
Howlett, N. G., Taniguchi, T., Olson, S., Cox, B., Waisfisz, Q., de Die-Smulders, C., Persky, N., Grompe, M., Joenje, H., Pals, G., et al. (2002) · Science
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 1,149
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A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
Cheloufi, S., Dos Santos, C. O., Chong, M. M. W., & Hannon, G. J. (2010) · Nature
MicroRNA in disease regulationRNA Interference and Gene Delivery
Cited by 1,149
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NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy
Pruitt, K. D., Tatusova, T., Brown, G. R., & Maglott, D. R. (2012) · Nucleic Acids Research
Genomics and Phylogenetic StudiesBiomedical Text Mining and Ontologies
Cited by 1,149
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Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity
You, X., Vlatkovic, I., Babic, A., Will, T., Epstein, I., Tushev, G., Akbalik, G., Wang, M., Glock, C., Quedenau, C., et al. (2015) · Nature Neuroscience
Circular RNAs in diseasesRNA Research and Splicing
Cited by 1,149
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Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
Powers, E. T., Morimoto, R. I., Dillin, A., Kelly, J. W., & Balch, W. E. (2009) · Annual Review of Biochemistry
Heat shock proteins researchEndoplasmic Reticulum Stress and Disease
Cited by 1,149
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The Nearly Neutral Theory of Molecular Evolution
Ohta, T. (1992) · Annual Review of Ecology and Systematics
Evolution and Genetic DynamicsGenetic diversity and population structure
Cited by 1,149
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Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
Zhu, Y., Tchkonia, T., Fuhrmann‐Stroissnigg, H., Dai, H. M., Ling, Y. Y., Stout, M. B., Pirtskhalava, T., Giorgadze, N., Johnson, K. O., Giles, C. B., et al. (2016) · Aging Cell
Telomeres, Telomerase, and SenescenceCell death mechanisms and regulation
Cited by 1,148
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Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
Stumvoll, M., Nurjhan, N., Perriello, G., Dailey, G., & Gerich, J. E. (1995) · New England Journal of Medicine
Metabolism, Diabetes, and CancerDiabetes Treatment and Management
Cited by 1,148
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Classification and evolution of P-loop GTPases and related ATPases
Leipe, D. D., Wolf, Y. I., Koonin, E. V., & Aravind, L. (2002) · Journal of Molecular Biology
RNA and protein synthesis mechanismsGenomics and Phylogenetic Studies
Cited by 1,148
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A human liver cell atlas reveals heterogeneity and epithelial progenitors
Aizarani, N., Saviano, A., Sagar, Mailly, L., Durand, S., Herman, J. S., Pessaux, P., Baumert, T. F., & Grün, D. (2019) · Nature
Single-cell and spatial transcriptomicsLiver physiology and pathology
Cited by 1,147
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Charting histone modifications and the functional organization of mammalian genomes
Zhou, V. W., Goren, A., & Bernstein, B. E. (2011) · Nature Reviews Genetics
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 1,147
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A rapid and robust method for single cell chromatin accessibility profiling
Chen, X., Miragaia, R. J., Natarajan, K. N., & Teichmann, S. A. (2018) · Nature Communications
Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics
Cited by 1,147
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Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
Balemans, W. (2001) · Human Molecular Genetics
Bone Metabolism and DiseasesDermatological and Skeletal Disorders
Cited by 1,147
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Chlamydomonas IFT 88 and Its Mouse Homologue, Polycystic Kidney Disease Gene Tg 737, Are Required for Assembly of Cilia and Flagella
Pazour, G. J., Dickert, B. L., Vucica, Y., Seeley, E. S., Rosenbaum, J. L., Witman, G. B., & Cole, D. G. (2000) · The Journal of Cell Biology
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 1,147
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Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
Martin, E. W., Holehouse, A. S., Peran, I., Farag, M., Incicco, J. J., Bremer, A., Grace, C. R., Soranno, A., Pappu, R. V., & Mittag, T. (2020) · Science
RNA Research and SplicingProtein Structure and Dynamics
Cited by 1,147
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Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark
Ruthenburg, A. J., Allis, C. D., & Wysocka, J. (2007) · Molecular Cell
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 1,147
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