Most cited biochemistry, genetics and molecular biology papers
- Verified
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
Chin, L., Artandi, S. E., Shen, Q., Tam, A., Lee, S.-L., Gottlieb, G. J., Greider, C. W., & DePinho, R. A. (1999) · Cell
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 979
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A Receptor for the Selective Uptake and Degradation of Proteins by Lysosomes
Cuervo, A. M., & Dice, J. F. (1996) · Science
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 979
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Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells
Wieckowski, M. R., Giorgi, C., Lebiedzinska, M., Duszynski, J., & Pinton, P. (2009) · Nature Protocols
Mitochondrial Function and PathologyIon Channels and Receptors
Cited by 979
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Accounting for technical noise in single-cell RNA-seq experiments
Brennecke, P., Anders, S., Kim, J. K., Kołodziejczyk, A. A., Zhang, X., Proserpio, V., Baying, B., Benes, V., Teichmann, S. A., Marioni, J. C., et al. (2013) · Nature Methods
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 979
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Essential role for nuclear PTEN in maintaining chromosomal integrity
Shen, W. H., Balajee, A. S., Wang, J., Wu, H., Eng, C., Pandolfi, P. P., & Yin, Y. (2007) · Cell
DNA Repair MechanismsMicrotubule and mitosis dynamics
Cited by 979
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Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface
Brose, N., Petrenko, A. G., Südhof, T. C., & Jahn, R. (1992) · Science
Cellular transport and secretionNeuroscience and Neuropharmacology Research
Cited by 979
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Protein kinase C and other diacylglycerol effectors in cancer
Griner, E. M., & Kazanietz, M. G. (2007) · Nature Reviews Cancer
Protein Kinase Regulation and GTPase SignalingSphingolipid Metabolism and Signaling
Cited by 978
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Liver X receptors as integrators of metabolic and inflammatory signaling
Zelcer, N. (2006) · Journal of Clinical Investigation
Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases
Cited by 978
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Generalized biomolecular modeling and design with RoseTTAFold All-Atom
Krishna, R., Wang, J., Ahern, W., Sturmfels, P., Venkatesh, P., Kalvet, I., Lee, G. R., Morey-Burrows, F. S., Anishchenko, I., Humphreys, I. R., et al. (2024) · Science
Protein Structure and DynamicsMachine Learning in Bioinformatics
Cited by 978
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Epithelial contact guidance on well-defined micro- and nanostructured substrates
Teixeira, A. I., Abrams, G. A., Bertics, P. J., Murphy, C. J., & Nealey, P. F. (2003) · Journal of Cell Science
Cellular Mechanics and Interactions3D Printing in Biomedical Research
Cited by 978
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p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells
Ihry, R. J., Worringer, K. A., Salick, M. R., Frias, E., Ho, D., Theriault, K., Kommineni, S., Chen, J., Sondey, M., Ye, C., et al. (2018) · Nature Medicine
CRISPR and Genetic EngineeringPluripotent Stem Cells Research
Cited by 978
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Tissue Distribution and Quantitative Analysis of Estrogen Receptor-α (ERα) and Estrogen Receptor-β (ERβ) Messenger Ribonucleic Acid in the Wild-Type and ERα-Knockout Mouse
Couse, J. F., Lindzey, J., Grandien, K., Gustafsson, J.-A., & Korach, K. S. (1997) · Endocrinology
Estrogen and related hormone effectsEffects and risks of endocrine disrupting chemicals
Cited by 978
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Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes.
Rapoport, T. A. (2007) · Nature
Cellular transport and secretionBacterial Genetics and Biotechnology
Cited by 977
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Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs
Gong, S., Doughty, M., Harbaugh, C. R., Cummins, A., Hatten, M. E., Heintz, N., & Gerfen, C. R. (2007) · The Journal of Neuroscience
Animal Genetics and ReproductionVirus-based gene therapy research
Cited by 977
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Stress and stability: applying the Anna Karenina principle to animal microbiomes
Zaneveld, J. R., McMinds, R., & Vega Thurber, R. (2017) · Nature Microbiology
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 977
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Safety and efficacy of vemurafenib in BRAFV600E and BRAFV600K mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study
McArthur, G. A., Chapman, P. B., Robert, C., Larkin, J., Haanen, J. B., Dummer, R., Ribas, A., Hogg, D., Hamid, O., Ascierto, P. A., et al. (2014) · The Lancet Oncology
Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management
Cited by 977
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Pyrosequencing study of fecal microflora of autistic and control children
Finegold, S. M., Dowd, S. E., Gontcharova, V., Liu, C., Henley, K. E., Wolcott, R. D., Youn, E., Summanen, P. H., Granpeesheh, D., Dixon, D., et al. (2010) · Anaerobe
Gut microbiota and healthAutism Spectrum Disorder Research
Cited by 977
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The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation.
Justice, R. W., Zilian, O., Woods, D. F., Noll, M., & Bryant, P. J. (1995) · Genes & Development
Hippo pathway signaling and YAP/TAZDevelopmental Biology and Gene Regulation
Cited by 977
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Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments
Yuan, Z., Li, Y., Zhang, S., Wang, X., Dou, H., Yu, X., Zhang, Z., Yang, S., & Xiao, M. (2023) · Molecular Cancer
Cellular Mechanics and InteractionsProtease and Inhibitor Mechanisms
Cited by 977
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Reduced incidence of Prevotella and other fermenters in intestinal microflora of autistic children
Kang, D.-W., Park, J. G., Ilhan, Z. E., Wallstrom, G., LaBaer, J., Adams, J. B., & Krajmalnik-Brown, R. (2013) · PLoS ONE
Gut microbiota and healthAutism Spectrum Disorder Research
Cited by 976
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Cell-type-specific isolation of ribosome-associated mRNA from complex tissues
Sanz, E., Yang, L., Su, T., Morris, D. R., McKnight, G. S., & Amieux, P. S. (2009) · Proceedings of the National Academy of Sciences
RNA and protein synthesis mechanismsRNA Research and Splicing
Cited by 976
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Organization of the mitotic chromosome
Naumova, N., Imakaev, M., Fudenberg, G., Zhan, Y., Lajoie, B. R., Mirny, L. A., & Dekker, J. (2013) · Science
Genomics and Chromatin DynamicsChromosomal and Genetic Variations
Cited by 976
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Human skin pigmentation: Melanocytes modulate skin color in response to stress
Costin, G.-E., & Hearing, V. J. (2007) · The FASEB Journal
melanin and skin pigmentationMelanoma and MAPK Pathways
Cited by 976
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Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
Shay, K. P., Moreau, R. F., Smith, E. J., Smith, A. R., & Hagen, T. M. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects
Biochemical Acid Research StudiesAldose Reductase and Taurine
Cited by 976
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