Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

The landscape of kinase fusions in cancer

Stransky, N., Cerami, E., Schalm, S., Kim, J. L., & Lengauer, C. (2014) · Nature Communications

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 968

The many roles of FAS receptor signaling in the immune system

Strasser, A., Jost, P. J., & Nagata, S. (2009) · Immunity

Cell death mechanisms and regulationT-cell and B-cell Immunology

Cited by 968

The Ink4/Arf locus is a barrier for iPS cell reprogramming

Li, H., Collado, M., Villasante, A., Strati, K., Ortega, S., Cañamero, M., Blasco, M. A., & Serrano, M. (2009) · Nature

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 968

Distribution of miRNA expression across human tissues

Ludwig, N., Leidinger, P., Becker, K., Backes, C., Fehlmann, T., Pallasch, C., Rheinheimer, S., Meder, B., Stähler, C., Meese, E., et al. (2016) · Nucleic Acids Research

MicroRNA in disease regulationGene expression and cancer classification

Cited by 968

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

Stenmark, H., Parton, R. G., Steele‐Mortimer, O., Lütcke, A., Gruenberg, J., & Zerial, M. (1994) · The EMBO Journal

Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling

Cited by 968

Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β

Dupont, N., Jiang, S., Pilli, M., Ornatowski, W., Bhattacharya, D., & Deretic, V. (2011) · The EMBO Journal

Autophagy in Disease and TherapyInflammasome and immune disorders

Cited by 967

Global Analysis of mRNA Localization Reveals a Prominent Role in Organizing Cellular Architecture and Function

Lécuyer, E., Yoshida, H., Parthasarathy, N., Alm, C., Babak, T., Cerovina, T., Hughes, T. R., Tomancak, P., & Krause, H. M. (2007) · Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 967

AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity

Chandarlapaty, S., Sawai, A., Scaltriti, M., Rodrik-Outmezguine, V., Grbovic-Huezo, O., Serra, V., Majumder, P. K., Baselga, J., & Rosen, N. (2011) · Cancer Cell

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 967

BRCA1 and BRCA2: 1994 and beyond

Narod, S. A., & Foulkes, W. D. (2004) · Nature Reviews Cancer

BRCA gene mutations in cancerGenetic factors in colorectal cancer

Cited by 967

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism

Cabreiro, F., Au, C., Leung, K.-Y., Vergara-Irigaray, N., Cochemé, H. M., Noori, T., Weinkove, D., Schuster, E., Greene, N. D. E., & Gems, D. (2013) · Cell

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 967

Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease

Panwar, V., Singh, A., Bhatt, M., Tonk, R. K., Azizov, S., Raza, A. S., Sengupta, S., Kumar, D., & Garg, M. (2023) · Signal Transduction and Targeted Therapy

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 967

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

Yuan, J., Amin, P., & Ofengeim, D. (2019) · Nature Reviews Neuroscience

Cell death mechanisms and regulationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 967

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1α

Ravi, R., Mookerjee, B., Bhujwalla, Z. M., Sutter, C. H., Artemov, D., Zeng, Q., Dillehay, L. E., Madan, A., Semenza, G. L., & Bedi, A. (2000) · Genes & Development

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 967

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2

Higuchi, M., Maas, S., Single, F. N., Hartner, J., Rozov, A., Burnashev, N., Feldmeyer, D., Sprengel, R., & Seeburg, P. H. (2000) · Nature

RNA regulation and diseaseRNA Research and Splicing

Cited by 967

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue

Liu, Y., Yang, M., Deng, Y., Su, G., Enninful, A., Guo, C. C., Tebaldi, T., Zhang, D., Kim, D., Bai, Z., et al. (2020) · Cell

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 966

Imaging dynamic and selective low-complexity domain interactions that control gene transcription

Chong, S., Dugast-Darzacq, C., Liu, Z., Dong, P., Dailey, G. M., Cattoglio, C., Heckert, A., Banala, S., Lavis, L., Darzacq, X., et al. (2018) · Science

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 966

Functional characterization of somatic mutations in cancer using network-based inference of protein activity

Alvarez, M. J., Shen, Y., Giorgi, F. M., Lachmann, A., Ding, B. B., Ye, B. H., & Califano, A. (2016) · Nature Genetics

Bioinformatics and Genomic NetworksCancer Genomics and Diagnostics

Cited by 966

Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

Jacks, T., Power, M. D., Masiarz, F. R., Luciw, P. A., Barr, P. J., & Varmus, H. E. (1988) · Nature

RNA and protein synthesis mechanismsHIV Research and Treatment

Cited by 966

Wall Teichoic Acids of Gram-Positive Bacteria

Brown, S., Santa Maria, J. P., & Walker, S. (2013) · Annual Review of Microbiology

Bacterial Genetics and BiotechnologyAntimicrobial Resistance in Staphylococcus

Cited by 966

Genotype Imputation with Thousands of Genomes

Howie, B., Marchini, J., & Stephens, M. (2011) · G3 Genes|Genomes|Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 966

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?

Schurch, N. J., Schofield, P., Gierliński, M., Cole, C., Sherstnev, A., Singh, V., Wrobel, N., Gharbi, K., Simpson, G. G., Owen-Hughes, T., et al. (2016) · RNA

Gene expression and cancer classificationGenomics and Phylogenetic Studies

Cited by 966

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

Zhang, J., Fujimoto, J., Zhang, J., Wedge, D. C., Song, X., Zhang, J., Seth, S., Chow, C.-W., Cao, Y., Gumbs, C., et al. (2014) · Science

Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations

Cited by 965

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

Najmabadi, H., Hu, H., Garshasbi, M., Zemojtel, T., Abedini, S. S., Chen, W., Hosseini, M., Behjati, F., Haas, S., Jamali, P., et al. (2011) · Nature

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

Cited by 965

Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle

Barrès, R., Yan, J., Egan, B., Treebak, J. T., Rasmussen, M., Fritz, T., Caidahl, K., Krook, A., O'Gorman, D. J., & Zierath, J. R. (2012) · Cell Metabolism

Epigenetics and DNA MethylationMuscle Physiology and Disorders

Cited by 965