Most cited biochemistry, genetics and molecular biology papers
- Verified
Digenome-seq: Genome-wide profiling of CRISPR-cas9 off-target effects in human cells
Kim, D., Bae, S., Park, J., Kim, E., Kim, S., Yu, H. R., Hwang, J., Kim, J.-I., & Kim, J.-S. (2015) · Nature Methods
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 992
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RETRACTED ARTICLE: APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
Nikolaev, A., McLaughlin, T., O’Leary, D. D. M., & Tessier-Lavigne, M. (2009) · Nature
Cell death mechanisms and regulationAlzheimer's disease research and treatments
Cited by 992
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Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer
Chung, W., Eum, H. H., Lee, H.-O., Lee, K.-M., Lee, H.-B., Kim, K.-T., Ryu, H. S., Kim, S., Lee, J. E., Park, Y. H., et al. (2017) · Nature Communications
Single-cell and spatial transcriptomicsCancer Genomics and Diagnostics
Cited by 992
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Nanomaterials based on DNA
Seeman, N. C. (2010) · Annual Review of Biochemistry
Advanced biosensing and bioanalysis techniquesDNA and Biological Computing
Cited by 992
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Serine and one-carbon metabolism in cancer
Yang, M., & Vousden, K. H. (2016) · Nature Reviews Cancer
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism
Cited by 992
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YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Weintraub, A. S., Li, C. H., Zamudio, A. V., Sigova, A. A., Hannett, N. M., Day, D. S., Abraham, B. J., Cohen, M. A., Nabet, B., Buckley, D. L., et al. (2017) · Cell
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 992
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Dsuite ‐ Fast D ‐statistics and related admixture evidence from VCF files
Malinsky, M., Matschiner, M., & Svardal, H. (2021) · Molecular Ecology Resources
Genetic diversity and population structureForensic and Genetic Research
Cited by 992
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Correction of a pathogenic gene mutation in human embryos
Ma, H., Marti-Gutierrez, N., Park, S.-W., Wu, J., Lee, Y., Suzuki, K., Koski, A., Ji, D., Hayama, T., Ahmed, R., et al. (2017) · Nature
CRISPR and Genetic EngineeringAnimal Genetics and Reproduction
Cited by 992
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Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
Zhang, X., Odom, D. T., Koo, S.-H., Conkright, M. D., Canettieri, G., Best, J., Chen, H., Jenner, R., Herbolsheimer, E., Jacobsen, E., et al. (2005) · Proceedings of the National Academy of Sciences
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 992
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Mediterranean Diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries
Ghosh, T. S., Rampelli, S., Jeffery, I. B., Santoro, A., Neto, M., Capri, M., Giampieri, E., Jennings, A., Candela, M., Turroni, S., et al. (2020) · Gut
Gut microbiota and healthNutritional Studies and Diet
Cited by 991
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Molecular mechanisms of translational control
Gebauer, F., & Hentze, M. W. (2004) · Nature Reviews Molecular Cell Biology
RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer
Cited by 991
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Incidence of diabetes in youth in the United States
SEARCH for Diabetes in Youth Study Group*, T. W. G. F. T. (2007) · JAMA
Diabetes and associated disordersDiabetes Management and Research
Cited by 991
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Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization
Iwase, T., Uehara, Y., Shinji, H., Tajima, A., Seo, H., Takada, K., Agata, T., & Mizunoe, Y. (2010) · Nature
Bacterial biofilms and quorum sensingAntimicrobial Resistance in Staphylococcus
Cited by 991
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Mitochondrial and metabolic dysfunction in ageing and age-related diseases
Amorim, J. A., Coppotelli, G., Rolo, A. P., Palmeira, C. M., Ross, J. M., & Sinclair, D. A. (2022) · Nature Reviews Endocrinology
Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms
Cited by 990
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Estrogen deficiency and bone loss: an inflammatory tale
Weitzmann, M. N. (2006) · Journal of Clinical Investigation
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 990
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Genotype Imputation
Li, Y., Willer, C., Sanna, S., & Abecasis, G. (2009) · Annual Review of Genomics and Human Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 990
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Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication
Sfeir, A., Kosiyatrakul, S. T., Hockemeyer, D., MacRae, S. L., Karlseder, J., Schildkraut, C. L., & de Lange, T. (2009) · Cell
Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms
Cited by 990
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The microbiome-gut-brain axis: from bowel to behavior
Cryan, J. F., & O’Mahony, S. M. (2011) · Neurogastroenterology & Motility
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 990
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Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
Sandoval, J., Heyn, H., Moran, S., Serra-Musach, J., Pujana, M. A., Bibikova, M., & Esteller, M. (2011) · Epigenetics
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 990
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Identification of slow molecular order parameters for Markov model construction
Pérez-Hernández, G., Paul, F., Giorgino, T., De Fabritiis, G., & Noé, F. (2013) · The Journal of Chemical Physics
Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions
Cited by 990
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Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
Mifsud, B., Tavares-Cadete, F., Young, A. N., Sugar, R., Schoenfelder, S., Ferreira, L., Wingett, S. W., Andrews, S., Grey, W., Ewels, P. A., et al. (2015) · Nature Genetics
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 990
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A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron
Shih, W. M., Quispe, J. D., & Joyce, G. F. (2004) · Nature
Advanced biosensing and bioanalysis techniquesDNA and Biological Computing
Cited by 989
- VerifiedRetracted
RETRACTED ARTICLE: Microbiome analyses of blood and tissues suggest cancer diagnostic approach
Poore, G. D., Kopylova, E., Zhu, Q., Carpenter, C., Fraraccio, S., Wandro, S., Kosciolek, T., Janssen, S., Metcalf, J., Song, S. J., et al. (2020) · Nature
Cancer Genomics and DiagnosticsGut microbiota and health
Cited by 989
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MicroRNA-mediated conversion of human fibroblasts to neurons
Yoo, A. S., Sun, A. X., Li, L., Shcheglovitov, A., Portmann, T., Li, Y., Lee-Messer, C., Dolmetsch, R. E., Tsien, R. W., & Crabtree, G. R. (2011) · Nature
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 989
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