Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Tumor Induction of VEGF Promoter Activity in Stromal Cells

Fukumura, D., Xavier, R., Sugiura, T., Chen, Y., Park, E.-C., Lu, N., Selig, M., Nielsen, G., Taksir, T., Jain, R. K., et al. (1998) · Cell

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 996

Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors

Moeller, B. J., Cao, Y., Li, C. Y., & Dewhirst, M. W. (2004) · Cancer Cell

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 996

Requirement for NF-κB in osteoclast and B-cell development

Franzoso, G., Carlson, L., Xing, L., Poljak, L., Shores, E. W., Brown, K. D., Leonardi, A., Tran, T., Boyce, B. F., & Siebenlist, U. (1997) · Genes & Development

NF-κB Signaling PathwaysBone Metabolism and Diseases

Cited by 996

New Users of Metformin Are at Low Risk of Incident Cancer

Libby, G., Donnelly, L. A., Donnan, P. T., Alessi, D. R., Morris, A. D., & Evans, J. M. M. (2009) · Diabetes Care

Metabolism, Diabetes, and CancerDiabetes Treatment and Management

Cited by 996

Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer

Fang, T., Lv, H., Lv, G., Li, T., Wang, C., Han, Q., Yu, L., Su, B., Guo, L., Huang, S., et al. (2018) · Nature Communications

Extracellular vesicles in diseaseMicroRNA in disease regulation

Cited by 995

Gene co-expression analysis for functional classification and gene–disease predictions

van Dam, S., Võsa, U., van der Graaf, A., Franke, L., & de Magalhães, J. P. (2017) · Briefings in Bioinformatics

Bioinformatics and Genomic NetworksGene expression and cancer classification

Cited by 995

Function and biological roles of the Dickkopf family of Wnt modulators

Niehrs, C. (2006) · Oncogene

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 995

Biochemistry of mammalian peroxisomes revisited

Wanders, R. J. A., & Waterham, H. R. (2006) · Annual Review of Biochemistry

Metabolism and Genetic DisordersPeroxisome Proliferator-Activated Receptors

Cited by 995

Molecular basis of the Keap1–Nrf2 system

Suzuki, T., & Yamamoto, M. (2015) · Free Radical Biology and Medicine

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 995

Scientific Opinion on risk based control of biogenic amine formation in fermented foods: Biogenic amines in fermented foods

(BIOHAZ), E. P. O. B. H. (2011) · EFSA Journal

Polyamine Metabolism and ApplicationsFermentation and Sensory Analysis

Cited by 995

Loss of the ClC-7 Chloride Channel Leads to Osteopetrosis in Mice and Man

Kornak, U., Kasper, D., Bösl, M. R., Kaiser, E., Schweizer, M., Schulz, A., Friedrich, W., Delling, G., & Jentsch, T. J. (2001) · Cell

Bone Metabolism and DiseasesIon channel regulation and function

Cited by 995

Pyruvate kinase M2 is a phosphotyrosine-binding protein

Christofk, H. R., Vander Heiden, M. G., Wu, N., Asara, J. M., & Cantley, L. C. (2008) · Nature

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 995

Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals

Asnicar, F., Berry, S. E., Valdes, A. M., Nguyen, L. H., Piccinno, G., Drew, D. A., Leeming, E., Gibson, R., Le Roy, C., Khatib, H. A., et al. (2021) · Nature Medicine

Gut microbiota and healthNutrition, Genetics, and Disease

Cited by 995

Improving the accuracy of two-sample summary-data Mendelian randomization: moving beyond the NOME assumption

Bowden, J., Del Greco M, F., Minelli, C., Zhao, Q., Lawlor, D. A., Sheehan, N. A., Thompson, J., & Davey Smith, G. (2019) · International Journal of Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 995

ClinVar: improvements to accessing data

Landrum, M. J., Chitipiralla, S., Brown, G. R., Chen, C., Gu, B., Hart, J., Hoffman, D., Jang, W., Kaur, K., Liu, C., et al. (2020) · Nucleic Acids Research

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 994

Rho‐kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

Amano, M., Nakayama, M., & Kaibuchi, K. (2010) · Cytoskeleton

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 994

Minireview: The AMP-Activated Protein Kinase Cascade: The Key Sensor of Cellular Energy Status

Hardie, D. G. (2003) · Endocrinology

Metabolism, Diabetes, and CancerBiochemical and Molecular Research

Cited by 994

A Novel Protein That Interacts with the Death Domain of Fas/APO1 Contains a Sequence Motif Related to the Death Domain

Boldin, M. P., Varfolomeev, E. E., Pancer, Z., Mett, I. L., Camonis, J. H., & Wallach, D. (1995) · Journal of Biological Chemistry

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 993

Next-generation DNA sequencing techniques

Ansorge, W. J. (2009) · New Biotechnology

Genomics and Phylogenetic StudiesGenomics and Rare Diseases

Cited by 993

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

Harris, I. S., Treloar, A. E., Inoue, S., Sasaki, M., Gorrini, C., Lee, K. C., Yung, K. Y., Brenner, D., Knobbe-Thomsen, C. B., Cox, M. A., et al. (2015) · Cancer Cell

Redox biology and oxidative stressGlutathione Transferases and Polymorphisms

Cited by 993

The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation

Donohoe, D. R., Collins, L. B., Wali, A., Bigler, R., Sun, W., & Bultman, S. J. (2012) · Molecular Cell

Histone Deacetylase Inhibitors ResearchCancer, Hypoxia, and Metabolism

Cited by 993

The core gut microbiome, energy balance and obesity

Turnbaugh, P. J., & Gordon, J. I. (2009) · The Journal of Physiology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 993

Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

Chan, N. C., Salazar, A. M., Pham, A. H., Sweredoski, M. J., Kolawa, N. J., Graham, R. L. J., Hess, S., & Chan, D. C. (2011) · Human Molecular Genetics

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 993

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

Rogov, V., Dötsch, V., Johansen, T., & Kirkin, V. (2014) · Molecular Cell

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 992