Most cited biochemistry, genetics and molecular biology papers
- Verified
Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells
Bintu, B., Mateo, L. J., Su, J.-H., Sinnott-Armstrong, N. A., Parker, M., Kinrot, S., Yamaya, K., Boettiger, A. N., & Zhuang, X. (2018) · Science
Genomics and Chromatin DynamicsAdvanced Fluorescence Microscopy Techniques
Cited by 976
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Apo2L/TRAIL-Dependent Recruitment of Endogenous FADD and Caspase-8 to Death Receptors 4 and 5
Kischkel, F. C., Lawrence, D. A., Chuntharapai, A., Schow, P., Kim, K. J., & Ashkenazi, A. (2000) · Immunity
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 975
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Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability
Wise, D. R., Ward, P. S., Shay, J. E. S., Cross, J. R., Gruber, J. J., Sachdeva, U. M., Platt, J. M., DeMatteo, R. G., Simon, M. C., & Thompson, C. B. (2011) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism
Cited by 975
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Intracellular and extracellular roles of S100 proteins
Donato, R. (2003) · Microscopy Research and Technique
S100 Proteins and AnnexinsAdvanced Glycation End Products research
Cited by 974
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PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription
Sandri, M., Lin, J., Handschin, C., Yang, W., Arany, Z. P., Lecker, S. H., Goldberg, A. L., & Spiegelman, B. M. (2006) · Proceedings of the National Academy of Sciences
Muscle Physiology and DisordersAdipose Tissue and Metabolism
Cited by 974
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The role of the gut microbiota in energy metabolism and metabolic disease
Cani, P., & Delzenne, N. (2009) · Current Pharmaceutical Design
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 974
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A Family of Sulfonylurea Receptors Determines the Pharmacological Properties of ATP-Sensitive K+ Channels
Inagaki, N., Gonoi, T., Iv, J. P. C., Wang, C.-Z., Aguilar-Bryan, L., Bryan, J., & Seino, S. (1996) · Neuron
Ion channel regulation and functionPancreatic function and diabetes
Cited by 974
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Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
Wolfrum, C., Shi, S., Jayaprakash, K. N., Jayaraman, M., Wang, G., Pandey, R. K., Rajeev, K. G., Nakayama, T., Charrise, K., Ndungo, E. M., et al. (2007) · Nature Biotechnology
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 974
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RAS isoforms and mutations in cancer at a glance
Hobbs, G. A., Der, C. J., & Rossman, K. L. (2016) · Journal of Cell Science
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 973
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Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives
Spruijt, C. G., Gnerlich, F., Smits, A. H., Pfaffeneder, T., Jansen, P. W. T. C., Bauer, C., Münzel, M., Wagner, M., Müller, M., Khan, F., et al. (2013) · Cell
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 973
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Highly Multiplexed Subcellular RNA Sequencing in Situ
Lee, J. H., Daugharthy, E. R., Scheiman, J., Kalhor, R., Yang, J. L., Ferrante, T. C., Terry, R., Jeanty, S. S. F., Li, C., Amamoto, R., et al. (2014) · Science
Single-cell and spatial transcriptomicsRNA Research and Splicing
Cited by 973
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Breast Cancer after Prophylactic Bilateral Mastectomy in Women with a BRCA1 or BRCA2 Mutation
Meijers-Heijboer, H., van Geel, B., van Putten, W. L. J., Henzen-Logmans, S. C., Seynaeve, C., Menke-Pluymers, M. B. E., Bartels, C. C. M., Verhoog, L. C., van den Ouweland, A. M. W., Niermeijer, M. F., et al. (2001) · New England Journal of Medicine
BRCA gene mutations in cancerWomen's cancer prevention and management
Cited by 973
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CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
Shukla, S., Kavak, E., Gregory, M., Imashimizu, M., Shutinoski, B., Kashlev, M., Oberdoerffer, P., Sandberg, R., & Oberdoerffer, S. (2011) · Nature
RNA Research and SplicingGenomics and Chromatin Dynamics
Cited by 973
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The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells
Seisenberger, S., Andrews, S., Krueger, F., Arand, J., Walter, J., Santos, F., Popp, C., Thienpont, B., Dean, W., & Reik, W. (2012) · Molecular Cell
Epigenetics and DNA MethylationPluripotent Stem Cells Research
Cited by 973
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Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
Tomas, E., Tsao, T.-S., Saha, A. K., Murrey, H. E., Zhang, C. C., Itani, S. I., Lodish, H. F., & Ruderman, N. B. (2002) · Proceedings of the National Academy of Sciences
Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism
Cited by 973
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Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues
Merkin, J., Russell, C., Chen, P., & Burge, C. B. (2012) · Science
RNA Research and SplicingGenomics and Phylogenetic Studies
Cited by 972
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The power of genetic diversity in genome-wide association studies of lipids
Graham, S. E., Clarke, S. L., Wu, K.-H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., et al. (2021) · Nature
Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health
Cited by 972
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α-Catenin as a tension transducer that induces adherens junction development
Yonemura, S., Wada, Y., Watanabe, T., Nagafuchi, A., & Shibata, M. (2010) · Nature Cell Biology
Cellular Mechanics and InteractionsCell Adhesion Molecules Research
Cited by 972
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Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity
Leclercq, S., Matamoros, S., Cani, P. D., Neyrinck, A. M., Jamar, F., Stärkel, P., Windey, K., Tremaroli, V., Bäckhed, F., Verbeke, K., et al. (2014) · Proceedings of the National Academy of Sciences
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 972
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Unmasking Transcriptional Heterogeneity in Senescent Cells
Hernandez-Segura, A., de Jong, T. V., Melov, S., Guryev, V., Campisi, J., & Demaria, M. (2017) · Current Biology
Telomeres, Telomerase, and SenescenceAdvanced biosensing and bioanalysis techniques
Cited by 972
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Mitochondrial Fusion and Fission in Mammals
Chan, D. C. (2006) · Annual Review of Cell and Developmental Biology
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 972
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The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex
Ellenberger, T. E., Brandl, C. J., Struhl, K., & Harrison, S. C. (1992) · Cell
Protein Structure and DynamicsGenomics and Chromatin Dynamics
Cited by 972
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Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
Shi, Y., Kirwan, P., & Livesey, F. J. (2012) · Nature Protocols
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 972
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An aged immune system drives senescence and ageing of solid organs
Yousefzadeh, M. J., Flores, R. R., Zhu, Y., Schmiechen, Z. C., Brooks, R. W., Trussoni, C. E., Cui, Y., Angelini, L., Lee, K.-A., McGowan, S. J., et al. (2021) · Nature
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 972
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