Most cited biochemistry, genetics and molecular biology papers
- Verified
Characterizing and measuring bias in sequence data
Ross, M. G., Russ, C., Costello, M., Hollinger, A., Lennon, N. J., Hegarty, R., Nusbaum, C., & Jaffe, D. B. (2013) · Genome Biology
Genomics and Phylogenetic StudiesFractal and DNA sequence analysis
Cited by 909
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The differential adhesion hypothesis: a direct evaluation
Foty, R. A., & Steinberg, M. S. (2005) · Developmental Biology
Cellular Mechanics and InteractionsCell Adhesion Molecules Research
Cited by 908
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Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
Hewitt, G., Jurk, D., Marques, F. D. M., Correia-Melo, C., Hardy, T., Gackowska, A., Anderson, R., Taschuk, M., Mann, J., & Passos, J. F. (2012) · Nature Communications
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 908
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Medium- and short-chain dehydrogenase/reductase gene and protein families: The SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes
Kavanagh, K. L., Jörnvall, H., Persson, B., & Oppermann, U. (2008) · Cellular and Molecular Life Sciences
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 908
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Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
Zhang, X., Yeung, D. C. Y., Karpisek, M., Stejskal, D., Zhou, Z.-G., Liu, F., Wong, R. L. C., Chow, W.-S., Tso, A. W. K., Lam, K. S. L., et al. (2008) · Diabetes
Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases
Cited by 908
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The relationship between force and focal complex development
Galbraith, C. G., Yamada, K. M., & Sheetz, M. P. (2002) · The Journal of Cell Biology
Cellular Mechanics and InteractionsCell Adhesion Molecules Research
Cited by 908
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Histone methylation in transcriptional control
Kouzarides, T. (2002) · Current Opinion in Genetics & Development
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 908
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Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits
Lupski, J. R. (1998) · Trends in Genetics
Genome Rearrangement AlgorithmsGenomic variations and chromosomal abnormalities
Cited by 908
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A comparison of background correction methods for two-colour microarrays
Ritchie, M. E., Silver, J., Oshlack, A., Holmes, M., Diyagama, D., Holloway, A., & Smyth, G. K. (2007) · Bioinformatics
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 907
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mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
García-Martínez, J. M., & Alessi, D. R. (2008) · Biochemical Journal
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling
Cited by 907
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The central role of DNA damage in the ageing process
Schumacher, B., Pothof, J., Vijg, J., & Hoeijmakers, J. H. J. (2021) · Nature
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 907
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Mutant sensory cilia in the nematode Caenorhabditis elegans
Perkins, L. A., Hedgecock, E. M., Thomson, J. N., & Culotti, J. G. (1986) · Developmental Biology
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 907
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Ligand-activated site-specific recombination in mice.
Feil, R., Brocard, J., Mascrez, B., LeMeur, M., Metzger, D., & Chambon, P. (1996) · Proceedings of the National Academy of Sciences
CRISPR and Genetic EngineeringAnimal Genetics and Reproduction
Cited by 907
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Genomic variation landscape of the human gut microbiome
Schloissnig, S., Arumugam, M., Sunagawa, S., Mitreva, M., Tap, J., Zhu, A., Waller, A., Mende, D. R., Kultima, J. R., Martin, J., et al. (2013) · Nature
Gut microbiota and healthGenomics and Phylogenetic Studies
Cited by 907
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The Nalp3 inflammasome is essential for the development of silicosis
Cassel, S. L., Eisenbarth, S. C., Iyer, S. S., Sadler, J. J., Colegio, O. R., Tephly, L. A., Carter, A. B., Rothman, P. B., Flavell, R. A., & Sutterwala, F. S. (2008) · Proceedings of the National Academy of Sciences
Inflammasome and immune disordersOccupational and environmental lung diseases
Cited by 907
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Oncogene jun encodes a sequence-specific trans- activator similar to AP-1
Angel, P., Allegretto, E. A., Okino, S. T., Hattori, K., Boyle, W. J., Hunter, T., & Karin, M. (1988) · Nature
Genomics and Chromatin DynamicsProtein Kinase Regulation and GTPase Signaling
Cited by 907
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Circuitry of nuclear factor κB signaling
Hoffmann, A., & Baltimore, D. (2006) · Immunological Reviews
NF-κB Signaling PathwaysImmune Response and Inflammation
Cited by 907
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Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development
Bendall, S. C., Davis, K. L., Amir, E.-A. D., Tadmor, M. D., Simonds, E. F., Chen, T. J., Shenfeld, D. K., Nolan, G. P., & Pe’er, D. (2014) · Cell
Single-cell and spatial transcriptomicsT-cell and B-cell Immunology
Cited by 906
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Cholesterol metabolism in the brain
Dietschy, J. M., & Turley, S. D. (2001) · Current Opinion in Lipidology
Cholesterol and Lipid MetabolismLipid Membrane Structure and Behavior
Cited by 906
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PHLPP: A phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
Gao, T., Furnari, F., & Newton, A. C. (2005) · Molecular Cell
PI3K/AKT/mTOR signaling in cancerProtein Tyrosine Phosphatases
Cited by 906
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The HLA System
Klein, J., & Sato, A. (2000) · New England Journal of Medicine
Genetic Associations and EpidemiologyRenal Transplantation Outcomes and Treatments
Cited by 906
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Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche
Ootani, A., Li, X., Sangiorgi, E., Ho, Q. T., Ueno, H., Toda, S., Sugihara, H., Fujimoto, K., Weissman, I. L., Capecchi, M. R., et al. (2009) · Nature Medicine
Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis
Cited by 906
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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
Heo, J.-M., Ordureau, A., Paulo, J. A., Rinehart, J., & Harper, J. W. (2015) · Molecular Cell
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 906
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Monitoring Bacterial Community of Human Gut Microbiota Reveals an Increase in Lactobacillus in Obese Patients and Methanogens in Anorexic Patients
Armougom, F., Henry, M., Vialettes, B., Raccah, D., & Raoult, D. (2009) · PLoS ONE
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 905
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