Most cited biochemistry, genetics and molecular biology papers
- Verified
RNA Sequencing and Analysis
Kukurba, K. R., & Montgomery, S. B. (2015) · Cold Spring Harbor Protocols
Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics
Cited by 924
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Telomeres and telomerase: three decades of progress
Shay, J. W., & Wright, W. E. (2019) · Nature Reviews Genetics
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 924
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A Role for AMP-Activated Protein Kinase in Contraction- and Hypoxia-Regulated Glucose Transport in Skeletal Muscle
Mu, J., Brozinick, J. T., Valladares, O., Bucan, M., & Birnbaum, M. J. (2001) · Molecular Cell
Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism
Cited by 924
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Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead
Bondeson, D. P., Smith, B. E., Burslem, G. M., Buhimschi, A. D., Hines, J., Jaime-Figueroa, S., Wang, J., Hamman, B. D., Ishchenko, A., & Crews, C. M. (2018) · Cell Chemical Biology
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 923
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Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans
Tullet, J. M. A., Hertweck, M., An, J. H., Baker, J., Hwang, J. Y., Liu, S., Oliveira, R. P., Baumeister, R., & Blackwell, T. K. (2008) · Cell
Genetics, Aging, and Longevity in Model OrganismsFOXO transcription factor regulation
Cited by 923
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PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers
Liu, R., Chen, Y., Liu, G., Li, C., Song, Y., Cao, Z., Li, W., Hu, J., Lu, C., & Liu, Y. (2020) · Cell Death & Disease
PI3K/AKT/mTOR signaling in cancerDrug Transport and Resistance Mechanisms
Cited by 923
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Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature
Rice, G. I., Kasher, P. R., Forte, G. M. A., Mannion, N. M., Greenwood, S. M., Szynkiewicz, M., Dickerson, J. E., Bhaskar, S. S., Zampini, M., Briggs, T. A., et al. (2012) · Nature Genetics
RNA regulation and diseaseinterferon and immune responses
Cited by 923
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Regulation of nucleosome dynamics by histone modifications
Zentner, G. E., & Henikoff, S. (2013) · Nature Structural & Molecular Biology
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 923
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Nika : software for two-dimensional data reduction
Ilavsky, J. (2012) · Journal of Applied Crystallography
Enzyme Structure and FunctionNuclear Physics and Applications
Cited by 923
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ATP-dependent chromatin remodeling: genetics, genomics and mechanisms
Hargreaves, D. C., & Crabtree, G. R. (2011) · Cell Research
Chromatin Remodeling and CancerGenomics and Chromatin Dynamics
Cited by 923
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Inferring the molecular and phenotypic impact of amino acid variants with MutPred2
Pejaver, V., Urresti, J., Lugo-Martinez, J., Pagel, K. A., Lin, G. N., Nam, H.-J., Mort, M., Cooper, D. N., Sebat, J., Iakoucheva, L. M., et al. (2020) · Nature Communications
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 923
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Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip
Kim, H. J., Li, H., Collins, J. J., & Ingber, D. E. (2016) · Proceedings of the National Academy of Sciences
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 922
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The Mediator complex: a central integrator of transcription
Allen, B. L., & Taatjes, D. J. (2015) · Nature Reviews Molecular Cell Biology
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 922
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CpG islands as gene markers in the human genome
Larsen, F., Gundersen, G., Lopez, R., & Prydz, H. (1992) · Genomics
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 922
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Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis
Kramann, R., Schneider, R. K., DiRocco, D. P., Machado, F., Fleig, S., Bondzie, P. A., Henderson, J. M., Ebert, B. L., & Humphreys, B. D. (2015) · Cell Stem Cell
Mesenchymal stem cell researchLiver physiology and pathology
Cited by 922
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Tissue-specific expression and regulation of sexually dimorphic genes in mice
Yang, X., Schadt, E. E., Wang, S., Wang, H., Arnold, A. P., Ingram-Drake, L., Drake, T. A., & Lusis, A. J. (2006) · Genome Research
Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesGenetic Mapping and Diversity in Plants and Animals
Cited by 922
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Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
Cantó, C., Jiang, L. Q., Deshmukh, A. S., Mataki, C., Coste, A., Lagouge, M., Zierath, J. R., & Auwerx, J. (2010) · Cell Metabolism
Metabolism, Diabetes, and CancerSirtuins and Resveratrol in Medicine
Cited by 921
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A copy number variation map of the human genome
Zarrei, M., MacDonald, J. R., Merico, D., & Scherer, S. W. (2015) · Nature Reviews Genetics
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 921
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Regulation of Mitochondrial Iron Accumulation by Yfh1p, a Putative Homolog of Frataxin
Babcock, M., de Silva, D., Oaks, R., Davis-Kaplan, S., Jiralerspong, S., Montermini, L., Pandolfo, M., & Kaplan, J. (1997) · Science
Mitochondrial Function and PathologyNeurological diseases and metabolism
Cited by 921
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3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets
Birmingham, A., Anderson, E. M., Reynolds, A., Ilsley-Tyree, D., Leake, D., Fedorov, Y., Baskerville, S., Maksimova, E., Robinson, K., Karpilow, J., et al. (2006) · Nature Methods
RNA Interference and Gene DeliveryCRISPR and Genetic Engineering
Cited by 920
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Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex
Pollen, A. A., Nowakowski, T. J., Shuga, J., Wang, X., Leyrat, A. A., Lui, J. H., Li, N., Szpankowski, L., Fowler, B., Chen, P., et al. (2014) · Nature Biotechnology
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 920
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A likelihood approach for comparing synonymous and nonsynonymous nucleotide substitution rates, with application to the chloroplast genome.
Muse, S. V., & Gaut, B. S. (1994) · Molecular Biology and Evolution
Genomics and Phylogenetic StudiesRNA and protein synthesis mechanisms
Cited by 920
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Influence of Metabolism on Epigenetics and Disease
Kaelin, W. G., & McKnight, S. L. (2013) · Cell
Epigenetics and DNA MethylationCancer, Hypoxia, and Metabolism
Cited by 920
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The Structure and Function of DNA G-Quadruplexes
Spiegel, J., Adhikari, S., & Balasubramanian, S. (2020) · Trends in Chemistry
DNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniques
Cited by 920
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