Most cited biochemistry, genetics and molecular biology papers
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GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
Aglietti, R. A., Estevez, A., Gupta, A., Ramirez, M. G., Liu, P. S., Kayagaki, N., Ciferri, C., Dixit, V. M., & Dueber, E. C. (2016) · Proceedings of the National Academy of Sciences
Inflammasome and immune disordersCell death mechanisms and regulation
Cited by 898
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IL-1 pathways in inflammation and human diseases
Gabay, C., Lamacchia, C., & Palmer, G. (2010) · Nature Reviews Rheumatology
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 897
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microRNAs in action: biogenesis, function and regulation
Shang, R., Lee, S., Senavirathne, G., & Lai, E. C. (2023) · Nature Reviews Genetics
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 897
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The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis
Cardone, R. A., Casavola, V., & Reshkin, S. J. (2005) · Nature Reviews Cancer
Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis
Cited by 897
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TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
Pastor, W. A., Aravind, L., & Rao, A. (2013) · Nature Reviews Molecular Cell Biology
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 897
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Exosomes are released by cultured cortical neurones
Fauré, J., Lachenal, G., Court, M., Hirrlinger, J., Chatellard-Causse, C., Blot, B., Grange, J., Schoehn, G., Goldberg, Y., Boyer, V., et al. (2006) · Molecular and Cellular Neuroscience
Extracellular vesicles in diseaseCellular transport and secretion
Cited by 896
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Subtilases: the superfamily of subtilisin-like serine proteases.
Siezen, R. J., & Leunissen, J. A. M. (1997) · Protein Science
Enzyme Production and CharacterizationEnzyme Structure and Function
Cited by 896
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Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
Thomas, K. R., & Capecchi, M. R. (1990) · Nature
Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms
Cited by 896
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Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury
Lee, C. G., Da Silva, C. A., Dela Cruz, C. S., Ahangari, F., Ma, B., Kang, M.-J., He, C.-H., Takyar, S., & Elias, J. A. (2011) · Annual Review of Physiology
Studies on Chitinases and ChitosanasesProteoglycans and glycosaminoglycans research
Cited by 896
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Application of Ozone for Enhancing the Microbiological Safety and Quality of Foods: A Review
Kim, J.-G., Yousef, A. E., & Dave, S. (1999) · Journal of Food Protection
Microbial Inactivation MethodsMedical and Biological Ozone Research
Cited by 896
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Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.
Schmidt, A. M., Hori, O., Chen, J. X., Li, J. F., Crandall, J., Zhang, J., Cao, R., Yan, S. D., Brett, J., & Stern, D. (1995) · Journal of Clinical Investigation
Advanced Glycation End Products researchCell Adhesion Molecules Research
Cited by 896
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Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
Miller, R. A., Harrison, D. E., Astle, C. M., Baur, J. A., Boyd, A. R., de Cabo, R., Fernandez, E., Flurkey, K., Javors, M. A., Nelson, J. F., et al. (2011) · The Journals of Gerontology: Series A
Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine
Cited by 896
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Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
Tan, J., Yang, X., Zhuang, L., Jiang, X., Chen, W., Lee, P. L., Karuturi, R. K. M., Tan, P. B. O., Liu, E. T., & Yu, Q. (2007) · Genes & Development
Epigenetics and DNA MethylationChromatin Remodeling and Cancer
Cited by 895
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Factors affecting the fermentative lactic acid production from renewable resources1
Hofvendahl, K., & Hahn–Hägerdal, B. (2000) · Enzyme and Microbial Technology
Microbial Metabolic Engineering and BioproductionBiofuel production and bioconversion
Cited by 895
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The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
Tugwood, J. D., Issemann, I., Anderson, R. G., Bundell, K. R., McPheat, W. L., & Green, S. (1992) · The EMBO Journal
Peroxisome Proliferator-Activated ReceptorsCholesterol and Lipid Metabolism
Cited by 895
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14-3-3σ is required to prevent mitotic catastrophe after DNA damage
Chan, T. A., Hermeking, H., Lengauer, C., Kinzler, K. W., & Vogelstein, B. (1999) · Nature
14-3-3 protein interactionsDNA Repair Mechanisms
Cited by 895
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A framework for understanding the functions of biomolecular condensates across scales
Lyon, A. S., Peeples, W. B., & Rosen, M. K. (2021) · Nature Reviews Molecular Cell Biology
RNA Research and SplicingNuclear Structure and Function
Cited by 895
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Control of microtubule organization and dynamics: Two ends in the limelight
Akhmanova, A., & Steinmetz, M. O. (2015) · Nature Reviews Molecular Cell Biology
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 895
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Hippo pathway effector Yap promotes cardiac regeneration
Xin, M., Kim, Y., Sutherland, L. B., Murakami, M., Qi, X., McAnally, J., Porrello, E. R., Mahmoud, A. I., Tan, W., Shelton, J. M., et al. (2013) · Proceedings of the National Academy of Sciences
Congenital heart defects researchHippo pathway signaling and YAP/TAZ
Cited by 895
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Proton pump inhibitors alter the composition of the gut microbiota
Jackson, M. A., Goodrich, J. K., Maxan, M.-E., Freedberg, D. E., Abrams, J. A., Poole, A. C., Sutter, J. L., Welter, D., Ley, R. E., Bell, J. T., et al. (2016) · Gut
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 895
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Stems Cells and the Pathways to Aging and Cancer
Rossi, D. J., Jamieson, C. H. M., & Weissman, I. L. (2008) · Cell
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 895
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Serotonin Receptors
Nichols, D. E., & Nichols, C. D. (2008) · Chemical Reviews
Receptor Mechanisms and SignalingNeurotransmitter Receptor Influence on Behavior
Cited by 895
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Amino acid signalling upstream of mTOR
Jewell, J. L., Russell, R. C., & Guan, K.-L. (2013) · Nature Reviews Molecular Cell Biology
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 894
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Regional variation limits applications of healthy gut microbiome reference ranges and disease models
He, Y., Wu, W., Zheng, H.-M., Li, P., McDonald, D., Sheng, H.-F., Chen, M.-X., Chen, Z.-H., Ji, G.-Y., Zheng, Z.-D.-X., et al. (2018) · Nature Medicine
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 894
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