Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Signaling to the Nucleus by an L-type Calcium Channel-Calmodulin Complex Through the MAP Kinase Pathway

Dolmetsch, R. E., Pajvani, U., Fife, K., Spotts, J. M., & Greenberg, M. E. (2001) · Science

Ion channel regulation and functionProtein Kinase Regulation and GTPase Signaling

Cited by 900

iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections

Janky, R., Verfaillie, A., Imrichová, H., Van de Sande, B., Standaert, L., Christiaens, V., Hulselmans, G., Herten, K., Naval Sanchez, M., Potier, D., et al. (2014) · PLoS Computational Biology

Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics

Cited by 900

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

Scully, R., Chen, J., Ochs, R. L., Keegan, K., Hoekstra, M., Feunteun, J., & Livingston, D. M. (1997) · Cell

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 900

Actin stress fibers – assembly, dynamics and biological roles

Tojkander, S., Gateva, G., & Lappalainen, P. (2012) · Journal of Cell Science

Cellular Mechanics and InteractionsSkin and Cellular Biology Research

Cited by 900

Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

Sugasawa, K., Ng, J. M. Y., Masutani, C., Iwai, S., van der Spek, P. J., Eker, A. P. M., Hanaoka, F., Bootsma, D., & Hoeijmakers, J. H. J. (1998) · Molecular Cell

DNA Repair MechanismsNuclear Structure and Function

Cited by 899

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

Nuñez, G., London, L., Hockenbery, D., Alexander, M., McKearn, J. P., & Korsmeyer, S. J. (1990) · The Journal of Immunology

Cell death mechanisms and regulationLymphoma Diagnosis and Treatment

Cited by 899

Proteostasis and aging

Kaushik, S., & Cuervo, A. M. (2015) · Nature Medicine

Genetics, Aging, and Longevity in Model OrganismsHeat shock proteins research

Cited by 899

Human saliva, plasma and breast milk exosomes contain RNA: Uptake by macrophages

Lässer, C., Seyed Alikhani, V., Ekström, K., Eldh, M., Torregrosa Paredes, P., Bossios, A., Sjöstrand, M., Gabrielsson, S., Lötvall, J., & Valadi, H. (2011) · Journal of Translational Medicine

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 899

Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

Ishihara, N., Fujita, Y., Oka, T., & Mihara, K. (2006) · The EMBO Journal

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 899

Senescence-associated β-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells

Kurz, D. J., Decary, S., Hong, Y., & Erusalimsky, J. D. (2000) · Journal of Cell Science

Telomeres, Telomerase, and SenescenceLysosomal Storage Disorders Research

Cited by 899

RNA-SeQC: RNA-seq metrics for quality control and process optimization

DeLuca, D. S., Levin, J. Z., Sivachenko, A., Fennell, T., Nazaire, M.-D., Williams, C., Reich, M., Winckler, W., & Getz, G. (2012) · Bioinformatics

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

Cited by 899

Retinol-binding protein: the transport protein for vitamin A in human plasma

Kanai, M., Raz, A., & Goodman, D. S. (1968) · Journal of Clinical Investigation

Retinoids in leukemia and cellular processesProtein Interaction Studies and Fluorescence Analysis

Cited by 899

Heritable genome editing in C. elegans via a CRISPR-Cas9 system

Friedland, A. E., Tzur, Y. B., Esvelt, K. M., Colaiácovo, M. P., Church, G. M., & Calarco, J. A. (2013) · Nature Methods

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 899

Forcing cells to change lineages

Graf, T., & Enver, T. (2009) · Nature

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 899

The most infectious prion protein particles

Silveira, J. R., Raymond, G. J., Hughson, A. G., Race, R. E., Sim, V. L., Hayes, S. F., & Caughey, B. (2005) · Nature

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 899

Early Lineage Segregation between Epiblast and Primitive Endoderm in Mouse Blastocysts through the Grb2-MAPK Pathway

Chazaud, C., Yamanaka, Y., Pawson, T., & Rossant, J. (2006) · Developmental Cell

Developmental Biology and Gene RegulationPluripotent Stem Cells Research

Cited by 898

The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression

De Bosscher, K., Vanden Berghe, W., & Haegeman, G. (2003) · Endocrine Reviews

NF-κB Signaling PathwaysEstrogen and related hormone effects

Cited by 898

Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA

Karikó, K., Muramatsu, H., Ludwig, J., & Weissman, D. (2011) · Nucleic Acids Research

RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms

Cited by 898

Chlamydomonas Kinesin-II–dependent Intraflagellar Transport (IFT): IFT Particles Contain Proteins Required for Ciliary Assembly in Caenorhabditis elegans Sensory Neurons

Cole, D. G., Diener, D. R., Himelblau, A. L., Beech, P. L., Fuster, J. C., & Rosenbaum, J. L. (1998) · The Journal of Cell Biology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 898

Molecular Actions of PPARα in Lipid Metabolism and Inflammation

Bougarne, N., Weyers, B., Desmet, S. J., Deckers, J., Ray, D. W., Staels, B., & De Bosscher, K. (2018) · Endocrine Reviews

Peroxisome Proliferator-Activated ReceptorsParaoxonase enzyme and polymorphisms

Cited by 898

Frequency of TERT promoter mutations in human cancers

Vinagre, J., Almeida, A., Pópulo, H., Batista, R., Lyra, J., Pinto, V., Coelho, R., Celestino, R., Prazeres, H., Lima, L., et al. (2013) · Nature Communications

Telomeres, Telomerase, and SenescenceCancer-related molecular mechanisms research

Cited by 898

Degradation of misfolded proteins in neurodegenerative diseases: Therapeutic targets and strategies

Ciechanover, A., & Kwon, Y. T. (2015) · Experimental & Molecular Medicine

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 898

Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase

Carey, A. L., Steinberg, G. R., Macaulay, S. L., Thomas, W. G., Holmes, A. G., Ramm, G., Prelovsek, O., Hohnen-Behrens, C., Watt, M. J., James, D. E., et al. (2006) · Diabetes

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 898

Human Telomerase and Its Regulation

Cong, Y.-S., Wright, W. E., & Shay, J. W. (2002) · Microbiology and Molecular Biology Reviews

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 898