Most cited biochemistry, genetics and molecular biology papers
- Verified
Recent advances in the development of protein–protein interactions modulators: mechanisms and clinical trials
Lu, H., Zhou, Q., He, J., Jiang, Z., Peng, C., Tong, R., & Shi, J. (2020) · Signal Transduction and Targeted Therapy
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 891
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Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity
Walmsley, S. R., Print, C., Farahi, N., Peyssonnaux, C., Johnson, R. S., Cramer, T., Sobolewski, A., Condliffe, A. M., Cowburn, A. S., Johnson, N., et al. (2005) · The Journal of Experimental Medicine
Cancer, Hypoxia, and MetabolismNeutrophil, Myeloperoxidase and Oxidative Mechanisms
Cited by 891
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The neuropharmacology of butyrate: the bread and butter of the microbiota-gut-brain axis
Stilling, R. M., van de Wouw, M., Clarke, G., Stanton, C., Dinan, T. G., & Cryan, J. F. (2016) · Neurochemistry International
Gut microbiota and healthNeuroscience and Neuropharmacology Research
Cited by 891
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Choreography of the DNA Damage Response
Lisby, M., Barlow, J. H., Burgess, R. C., & Rothstein, R. (2004) · Cell
DNA Repair MechanismsFungal and yeast genetics research
Cited by 891
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Lysosomal positioning coordinates cellular nutrient responses
Korolchuk, V. I., Saiki, S., Lichtenberg, M., Siddiqi, F. H., Roberts, E. A., Imarisio, S., Jahreiss, L., Sarkar, S., Futter, M., Menzies, F. M., et al. (2011) · Nature Cell Biology
Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer
Cited by 891
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Multi-platform discovery of haplotype-resolved structural variation in human genomes
Chaisson, M. J. P., Sanders, A. D., Zhao, X., Malhotra, A., Porubsky, D., Rausch, T., Gardner, E. J., Rodriguez, O. L., Guo, L., Collins, R. L., et al. (2019) · Nature Communications
Genomic variations and chromosomal abnormalitiesGenomics and Phylogenetic Studies
Cited by 891
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‘Infotaxis’ as a strategy for searching without gradients
Vergassola, M., Villermaux, E., & Shraiman, B. I. (2007) · Nature
Diffusion and Search DynamicsInsect Pheromone Research and Control
Cited by 890
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Genome partitioning of genetic variation for complex traits using common SNPs
Yang, J., Manolio, T. A., Pasquale, L. R., Boerwinkle, E., Caporaso, N., Cunningham, J. M., de Andrade, M., Feenstra, B., Feingold, E., Hayes, M. G., et al. (2011) · Nature Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 890
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TGF-β signaling in health and disease
Massagué, J., & Sheppard, D. (2023) · Cell
TGF-β signaling in diseasesLiver physiology and pathology
Cited by 890
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Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease
Palmer, M. S., Dryden, A. J., Hughes, J. T., & Collinge, J. (1991) · Nature
Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments
Cited by 890
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DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells
Yagi, M., Miyamoto, T., Sawatani, Y., Iwamoto, K., Hosogane, N., Fujita, N., Morita, K., Ninomiya, K., Suzuki, T., Miyamoto, K., et al. (2005) · The Journal of Experimental Medicine
Bone Metabolism and DiseasesPhagocytosis and Immune Regulation
Cited by 890
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Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age
Corral-Debrinski, M., Horton, T., Lott, M. T., Shoffner, J. M., Flint Beal, M., & Wallace, D. C. (1992) · Nature Genetics
Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms
Cited by 890
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Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture
Laurent, L. C., Ulitsky, I., Slavin, I., Tran, H., Schork, A., Morey, R., Lynch, C., Harness, J. V., Lee, S., Barrero, M. J., et al. (2011) · Cell stem cell
Pluripotent Stem Cells ResearchGenomic variations and chromosomal abnormalities
Cited by 890
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Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin
Plotkin, L. I., Weinstein, R. S., Parfitt, A. M., Roberson, P. K., Manolagas, S. C., & Bellido, T. (1999) · Journal of Clinical Investigation
Bone Metabolism and DiseasesBone health and treatments
Cited by 890
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Fluorescence lifetime imaging – techniques and applications
BECKER, W. (2012) · Journal of Microscopy
Advanced Fluorescence Microscopy TechniquesPhotochemistry and Electron Transfer Studies
Cited by 890
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HEF1-Dependent Aurora A Activation Induces Disassembly of the Primary Cilium
Pugacheva, E. N., Jablonski, S. A., Hartman, T. R., Henske, E. P., & Golemis, E. A. (2007) · Cell
Genetic and Kidney Cyst DiseasesMicrotubule and mitosis dynamics
Cited by 890
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Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner
Kalender, A., Selvaraj, A., Kim, S. Y., Gulati, P., Brûlé, S., Viollet, B., Kemp, B. E., Bardeesy, N., Dennis, P., Schlager, J. J., et al. (2010) · Cell Metabolism
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 889
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The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
MAQC Consortium (2010) · Nature Biotechnology
Gene expression and cancer classificationBreast Cancer Treatment Studies
Cited by 889
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The tumorigenicity of human embryonic and induced pluripotent stem cells
Ben-David, U., & Benvenisty, N. (2011) · Nature Reviews Cancer
Pluripotent Stem Cells ResearchCancer Cells and Metastasis
Cited by 889
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MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development
O'Connell, R. M., Kahn, D., Gibson, W. S. J., Round, J. L., Scholz, R. L., Chaudhuri, A. A., Kahn, M. E., Rao, D. S., & Baltimore, D. (2010) · Immunity
MicroRNA in disease regulationT-cell and B-cell Immunology
Cited by 889
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Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex
Li, V. S. W., Ng, S. S., Boersema, P. J., Low, T. Y., Karthaus, W. R., Gerlach, J. P., Mohammed, S., Heck, A. J. R., Maurice, M. M., Mahmoudi, T., et al. (2012) · Cell
Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease
Cited by 889
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The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
Mogilyansky, E., & Rigoutsos, I. (2013) · Cell Death & Differentiation
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 889
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The PhenX Toolkit: get the most from your measures
Hamilton, C. M., Strader, L. C., Pratt, J. G., Maiese, D., Hendershot, T., Kwok, R. K., Hammond, J. A., Huggins, W., Jackman, D., Pan, H., et al. (2011) · American Journal of Epidemiology
Genetic Associations and EpidemiologyHealth, Environment, Cognitive Aging
Cited by 889
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Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins
Wood, I. S., & Trayhurn, P. (2003) · British Journal of Nutrition
Metabolism, Diabetes, and CancerIon Transport and Channel Regulation
Cited by 889
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