Most cited biochemistry, genetics and molecular biology papers
- Verified
The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., & Thompson, C. B. (2008) · Cell Metabolism
Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism
Cited by 4,088
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Functional mapping and annotation of genetic associations with FUMA
Watanabe, K., Taskesen, E., van Bochoven, A., & Posthuma, D. (2017) · Nature Communications
Bioinformatics and Genomic NetworksGenetic Associations and Epidemiology
Cited by 4,083
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Lipid nanoparticles for mRNA delivery
Hou, X., Zaks, T., Langer, R., & Dong, Y. (2021) · Nature Reviews Materials
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 4,076
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Molecular characterization of mitochondrial apoptosis-inducing factor
Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Snow, B. E., Brothers, G. M., Mangion, J., Jacotot, E., Costantini, P., Loeffler, M., et al. (1999) · Nature
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 4,060
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mixOmics: An R package for ‘omics feature selection and multiple data integration
Rohart, F., Gautier, B., Singh, A., & Lê Cao, K.-A. (2017) · PLOS Computational Biology
Bioinformatics and Genomic NetworksMetabolomics and Mass Spectrometry Studies
Cited by 4,056
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MicroRNA Gene Expression Deregulation in Human Breast Cancer
Iorio, M. V., Ferracin, M., Liu, C.-G., Veronese, A., Spizzo, R., Sabbioni, S., Magri, E., Pedriali, M., Fabbri, M., Campiglio, M., et al. (2005) · Cancer Research
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 4,053
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Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
Shi, Y., Lan, F., Matson, C., Mulligan, P., Whetstine, J. R., Cole, P. A., Casero, R. A., & Shi, Y. (2004) · Cell
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 4,051
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Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
Yang, W., Soares, J., Greninger, P., Edelman, E. J., Lightfoot, H., Forbes, S., Bindal, N., Beare, D., Smith, J. A., Thompson, I. R., et al. (2012) · Nucleic Acids Research
Cancer Genomics and DiagnosticsComputational Drug Discovery Methods
Cited by 4,051
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Genetic effects on gene expression across human tissues
GTEx Consortium (2017) · Nature
Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics
Cited by 4,036
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Rapid and sensitive protein similarity searches
Lipman, D. J., & Pearson, W. R. (1985) · Science
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 4,033
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The Bcl2 family: regulators of the cellular life-or-death switch
Cory, S., & Adams, J. M. (2002) · Nature Reviews Cancer
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 4,032
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Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
Mahley, R. W. (1988) · Science
Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health
Cited by 4,028
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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Narendra, D., Tanaka, A., Suen, D.-F., & Youle, R. J. (2008) · The Journal of Cell Biology
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 4,026
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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
Duewell, P., Kono, H., Rayner, K. J., Sirois, C. M., Vladimer, G., Bauernfeind, F. G., Abela, G. S., Franchi, L., Nuñez, G., Schnurr, M., et al. (2010) · Nature
Inflammasome and immune disordersAtherosclerosis and Cardiovascular Diseases
Cited by 4,026
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qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
Hellemans, J., Mortier, G., De Paepe, A., Speleman, F., & Vandesompele, J. (2007) · Genome Biology
Molecular Biology Techniques and ApplicationsGene expression and cancer classification
Cited by 4,023
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The landscape of somatic copy-number alteration across human cancers
Beroukhim, R., Mermel, C. H., Porter, D., Wei, G., Raychaudhuri, S., Donovan, J., Barretina, J., Boehm, J. S., Dobson, J., Urashima, M., et al. (2010) · Nature
Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities
Cited by 4,017
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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
Hindorff, L. A., Sethupathy, P., Junkins, H. A., Ramos, E. M., Mehta, J. P., Collins, F. S., & Manolio, T. A. (2009) · Proceedings of the National Academy of Sciences
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 4,013
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Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member
McPherron, A. C., Lawler, A. M., & Lee, S.-J. (1997) · Nature
Muscle Physiology and DisordersTGF-β signaling in diseases
Cited by 4,013
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Amino acid metabolism in Mammalian cell cultures
Eagle, H. (1959) · Science
Amino Acid Enzymes and MetabolismRNA and protein synthesis mechanisms
Cited by 4,011
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NF-κB regulation in the immune system
Li, Q., & Verma, I. M. (2002) · Nature Reviews Immunology
NF-κB Signaling PathwaysImmune Response and Inflammation
Cited by 4,007
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The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
Buniello, A., MacArthur, J. A. L., Cerezo, M., Harris, L. W., Hayhurst, J., Malangone, C., McMahon, A., Morales, J., Mountjoy, E., Sollis, E., et al. (2019) · Nucleic Acids Research
Genetic Associations and EpidemiologyBioinformatics and Genomic Networks
Cited by 4,000
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An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements
Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., et al. (1997) · Biochemical and Biophysical Research Communications
Genomics, phytochemicals, and oxidative stressGlutathione Transferases and Polymorphisms
Cited by 3,999
- Verified
Guidelines for the use and interpretation of assays for monitoring autophagy
Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 3,996
- Verified
The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications
Sharp, P. M., & Li, W.-H. (1987) · Nucleic Acids Research
RNA and protein synthesis mechanismsGenomics and Phylogenetic Studies
Cited by 3,992
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