Most cited biochemistry, genetics and molecular biology papers
- Verified
Genetic studies of body mass index yield new insights for obesity biology
Study, T. L. C., Locke, A. E., The ADIPOGen Consortium, The AGEN-BMI Working Group, The CARDIOGRAMplusC4D Consortium, The CKDGen Consortium, The, G. L. G. C., The, I. C. B. P., The MAGIC Investigators, The MuTHER Consortium, et al. (2015) · Nature
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 4,534
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A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity
Frayling, T. M., Timpson, N. J., Weedon, M. N., Zeggini, E., Freathy, R. M., Lindgren, C. M., Perry, J. R. B., Elliott, K. S., Lango, H., Rayner, N. W., et al. (2007) · Science
Genetic Associations and EpidemiologyGenetics and Physical Performance
Cited by 4,531
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DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors
McGinnis, C. S., Murrow, L. M., & Gartner, Z. J. (2019) · Cell Systems
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 4,521
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Kraken: ultrafast metagenomic sequence classification using exact alignments
Wood, D. E., & Salzberg, S. L. (2014) · Genome Biology
Genomics and Phylogenetic StudiesEnvironmental DNA in Biodiversity Studies
Cited by 4,521
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The Epigenomics of Cancer
Jones, P. A., & Baylin, S. B. (2007) · Cell
Epigenetics and DNA MethylationChromatin Remodeling and Cancer
Cited by 4,515
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Human mesenchymal stem cells modulate allogeneic immune cell responses
Aggarwal, S., & Pittenger, M. F. (2005) · Blood
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 4,511
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Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
Everard, A., Belzer, C., Geurts, L., Ouwerkerk, J. P., Druart, C., Bindels, L. B., Guiot, Y., Derrien, M., Muccioli, G. G., Delzenne, N. M., et al. (2013) · Proceedings of the National Academy of Sciences
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 4,511
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Next-generation DNA sequencing
Shendure, J., & Ji, H. (2008) · Nature Biotechnology
Genomics and Phylogenetic StudiesGenetics, Bioinformatics, and Biomedical Research
Cited by 4,509
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CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
Chen, J. S., Ma, E., Harrington, L. B., Da Costa, M., Tian, X., Palefsky, J. M., & Doudna, J. A. (2018) · Science
CRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniques
Cited by 4,507
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Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells
Boyer, L. A., Lee, T. I., Cole, M. F., Johnstone, S. E., Levine, S. S., Zucker, J. P., Guenther, M. G., Kumar, R. M., Murray, H. L., Jenner, R. G., et al. (2005) · Cell
Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation
Cited by 4,505
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GREAT improves functional interpretation of cis-regulatory regions
McLean, C. Y., Bristor, D., Hiller, M., Clarke, S. L., Schaar, B. T., Lowe, C. B., Wenger, A. M., & Bejerano, G. (2010) · Nature Biotechnology
Genomics and Chromatin DynamicsBioinformatics and Genomic Networks
Cited by 4,502
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PEAR: a fast and accurate Illumina Paired-End reAd mergeR
Zhang, J., Kobert, K., Flouri, T., & Stamatakis, A. (2014) · Bioinformatics
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 4,497
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Methods in Mammalian Autophagy Research
Mizushima, N., Yoshimori, T., & Levine, B. (2010) · Cell
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 4,497
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metaSPAdes: a new versatile metagenomic assembler
Nurk, S., Meleshko, D., Korobeynikov, A., & Pevzner, P. A. (2017) · Genome Research
Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology
Cited by 4,496
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Cellular and molecular mechanisms of fibrosis
Wynn, T. (2008) · The Journal of Pathology
TGF-β signaling in diseasesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Cited by 4,495
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The single-cell transcriptional landscape of mammalian organogenesis
Cao, J., Spielmann, M., Qiu, X., Huang, X., Ibrahim, D. M., Hill, A. J., Zhang, F., Mundlos, S., Christiansen, L., Steemers, F. J., et al. (2019) · Nature
Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation
Cited by 4,490
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Endostatin: an endogenous inhibitor of angiogenesis and tumor growth
O'Reilly, M. S., Boehm, T., Shing, Y., Fukai, N., Vasios, G., Lane, W. S., Flynn, E., Birkhead, J. R., Olsen, B. R., & Folkman, J. (1997) · Cell
Angiogenesis and VEGF in CancerVascular Tumors and Angiosarcomas
Cited by 4,486
- Verified
Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression
Hafemeister, C., & Satija, R. (2019) · Genome Biology
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 4,479
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Twenty-Year Follow-up of a Randomized Study Comparing Breast-Conserving Surgery with Radical Mastectomy for Early Breast Cancer
Veronesi, U., Cascinelli, N., Mariani, L., Greco, M., Saccozzi, R., Luini, A., Aguilar, M., & Marubini, E. (2002) · New England Journal of Medicine
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 4,450
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Common SNPs explain a large proportion of the heritability for human height
Yang, J., Benyamin, B., McEvoy, B. P., Gordon, S., Henders, A. K., Nyholt, D. R., Madden, P. A., Heath, A. C., Martin, N. G., Montgomery, G. W., et al. (2010) · Nature Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 4,446
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Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Li, H., Zhu, H., Xu, C.-J., & Yuan, J. (1998) · Cell
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 4,445
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Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β
Kuiper, G. G. J. M., Carlsson, B., Grandien, K., Enmark, E., Häggblad, J., Nilsson, S., & Gustafsson, J.-A. (1997) · Endocrinology
Estrogen and related hormone effectsEffects and risks of endocrine disrupting chemicals
Cited by 4,442
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Cellular senescence: when bad things happen to good cells
Campisi, J., & d'Adda di Fagagna, F. (2007) · Nature Reviews Molecular Cell Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 4,441
- Verified
A second generation human haplotype map of over 3.1 million SNPs
The International HapMap Consortium (2007) · Nature
Genetic Associations and EpidemiologyForensic and Genetic Research
Cited by 4,438
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