Most cited biochemistry, genetics and molecular biology papers
- Verified
The landscape of somatic mutation in normal colorectal epithelial cells
Lee-Six, H., Olafsson, S., Ellis, P., Osborne, R. J., Sanders, M. A., Moore, L., Georgakopoulos, N., Torrente, F., Noorani, A., Goddard, M., et al. (2019) · Nature
Cancer Genomics and DiagnosticsGenetic factors in colorectal cancer
Cited by 747
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Identification and Functional Expression of the Mitochondrial Pyruvate Carrier
Herzig, S., Raemy, E., Montessuit, S., Veuthey, J.-L., Zamboni, N., Westermann, B., Kunji, E. R. S., & Martinou, J.-C. (2012) · Science
Mitochondrial Function and PathologyATP Synthase and ATPases Research
Cited by 747
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Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus
Bennett, S. T., Lucassen, A. M., Gough, S. C. L., Powell, E. E., Undlien, D. E., Pritchard, L. E., Merriman, M. E., Kawaguchi, Y., Dronsfield, M. J., Pociot, F., et al. (1995) · Nature Genetics
Diabetes and associated disordersGenetic Associations and Epidemiology
Cited by 746
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Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway
Diehl, J. A., Zindy, F., & Sherr, C. J. (1997) · Genes & Development
Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways
Cited by 746
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Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos
Liu, X., Wang, C., Liu, W., Li, J., Li, C., Kou, X., Chen, J., Zhao, Y., Gao, H., Wang, H., et al. (2016) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 746
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Control of the repetitive discharge of rat CA 1 pyramidal neurones in vitro.
Madison, D. V., & Nicoll, R. A. (1984) · The Journal of Physiology
Ion channel regulation and functionNeuroscience and Neuropharmacology Research
Cited by 746
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Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles
The Breast Cancer Susceptibility Collaboration (UK), Seal, S., Thompson, D., Renwick, A., Elliott, A., Kelly, P., Barfoot, R., Chagtai, T., Jayatilake, H., Ahmed, M., et al. (2006) · Nature Genetics
BRCA gene mutations in cancerDNA Repair Mechanisms
Cited by 746
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RANK Is the Essential Signaling Receptor for Osteoclast Differentiation Factor in Osteoclastogenesis
Nakagawa, N., Kinosaki, M., Yamaguchi, K., Shima, N., Yasuda, H., Yano, K., Morinaga, T., & Higashio, K. (1998) · Biochemical and Biophysical Research Communications
Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies
Cited by 746
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Control of Kinetic Properties of AMPA Receptor Channels by Nuclear RNA Editing
Lomeli, H., Mosbacher, J., Melcher, T., Höger, T., Geiger, J. R. P., Kuner, T., Monyer, H., Higuchi, M., Bach, A., & Seeburg, P. H. (1994) · Science
RNA regulation and diseaseNeuroscience and Neuropharmacology Research
Cited by 746
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Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF
Helms, J. B., & Rothman, J. E. (1992) · Nature
Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling
Cited by 746
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High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources
Haraszti, R. A., Didiot, M., Sapp, E., Leszyk, J., Shaffer, S. A., Rockwell, H. E., Gao, F., Narain, N. R., DiFiglia, M., Kiebish, M. A., et al. (2016) · Journal of Extracellular Vesicles
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 746
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A superfamily of conserved domains in DNA damage‐ responsive cell cycle checkpoint proteins
Bork, P., Hofmann, K., Bucher, P., Neuwald, A. F., Altschul, S. F., & Koonin, E. V. (1997) · The FASEB Journal
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 746
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Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines
Yanagida, O., Kanai, Y., Chairoungdua, A., Kim, D. K., Segawa, H., Nii, T., Cha, S. H., Matsuo, H., Fukushima, J.-I., Fukasawa, Y., et al. (2001) · Biochimica et Biophysica Acta (BBA) - Biomembranes
Amino Acid Enzymes and MetabolismCancer, Hypoxia, and Metabolism
Cited by 746
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Structural biology of the Bcl-2 family of proteins
Petros, A. M., Olejniczak, E. T., & Fesik, S. W. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Cell death mechanisms and regulationEnzyme Structure and Function
Cited by 745
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Trafficking and function of the tetraspanin CD63
Pols, M. S., & Klumperman, J. (2009) · Experimental Cell Research
Cellular transport and secretionCell Adhesion Molecules Research
Cited by 745
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Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
Study, T. L. C., Yang, J., Bakshi, A., Zhu, Z., Hemani, G., Vinkhuyzen, A. A. E., Lee, S. H., Robinson, M. R., Perry, J. R. B., Nolte, I. M., et al. (2015) · Nature Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 745
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Inflammatory memory sensitizes skin epithelial stem cells to tissue damage
Naik, S., Larsen, S. B., Gomez, N. C., Alaverdyan, K., Sendoel, A., Yuan, S., Polak, L., Kulukian, A., Chai, S., & Fuchs, E. (2017) · Nature
Inflammasome and immune disordersHair Growth and Disorders
Cited by 745
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The glyoxylate cycle is required for fungal virulence
Lorenz, M. C., & Fink, G. R. (2001) · Nature
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 745
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Using Gene Expression Noise to Understand Gene Regulation
Munsky, B., Neuert, G., & van Oudenaarden, A. (2012) · Science
Gene Regulatory Network Analysisstochastic dynamics and bifurcation
Cited by 745
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The BioPAX community standard for pathway data sharing
Demir, E., Cary, M. P., Paley, S., Fukuda, K., Lemer, C., Vastrik, I., Wu, G., D'Eustachio, P., Schaefer, C., Luciano, J., et al. (2010) · Nature Biotechnology
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 745
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The chemical repertoire of natural ribozymes
Doudna, J. A., & Cech, T. R. (2002) · Nature
RNA and protein synthesis mechanismsOrigins and Evolution of Life
Cited by 745
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Sialic Acids in the Brain: Gangliosides and Polysialic Acid in Nervous System Development, Stability, Disease, and Regeneration
Schnaar, R. L., Gerardy-Schahn, R., & Hildebrandt, H. (2014) · Physiological Reviews
Glycosylation and Glycoproteins ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 745
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Small Talk
Bassler, B. L. (2002) · Cell
Bacterial biofilms and quorum sensingBacterial Genetics and Biotechnology
Cited by 745
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Telomeres in cancer: tumour suppression and genome instability
Maciejowski, J., & de Lange, T. (2017) · Nature Reviews Molecular Cell Biology
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 745
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