Most cited biochemistry, genetics and molecular biology papers
- Verified
Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage
Yoshida, K., & Miki, Y. (2004) · Cancer Science
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 753
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IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
Rokavec, M., Öner, M. G., Li, H., Jackstadt, R., Jiang, L., Lodygin, D., Kaller, M., Horst, D., Ziegler, P. K., Schwitalla, S., et al. (2014) · Journal of Clinical Investigation
MicroRNA in disease regulationCytokine Signaling Pathways and Interactions
Cited by 753
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Metabolic Control of Longevity
López-Otín, C., Galluzzi, L., Freije, J. M. P., Madeo, F., & Kroemer, G. (2016) · Cell
Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine
Cited by 753
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mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake
Yilmaz, Ö. H., Katajisto, P., Lamming, D. W., Gültekin, Y., Bauer-Rowe, K. E., Sengupta, S., Birsoy, K., Dursun, A., Yilmaz, V. O., Selig, M., et al. (2012) · Nature
PI3K/AKT/mTOR signaling in cancerGenetics, Aging, and Longevity in Model Organisms
Cited by 753
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β-catenin: a key mediator of Wnt signaling
Willert, K., & Nusse, R. (1998) · Current Opinion in Genetics & Development
Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease
Cited by 753
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Atg8 Controls Phagophore Expansion during Autophagosome Formation
Xie, Z., Nair, U., & Klionsky, D. J. (2008) · Molecular Biology of the Cell
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 753
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Natural β-sheet proteins use negative design to avoid edge-to-edge aggregation
Richardson, J. S., & Richardson, D. C. (2002) · Proceedings of the National Academy of Sciences
Protein Structure and DynamicsChemical Synthesis and Analysis
Cited by 753
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The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease
Yang, T., Richards, E. M., Pepine, C. J., & Raizada, M. K. (2018) · Nature Reviews Nephrology
Gut microbiota and healthChronic Kidney Disease and Diabetes
Cited by 753
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Androgen Receptor (AR) Coregulators: A Diversity of Functions Converging on and Regulating the AR Transcriptional Complex
Heemers, H. V., & Tindall, D. J. (2007) · Endocrine Reviews
Prostate Cancer Treatment and ResearchEstrogen and related hormone effects
Cited by 753
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Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
Flyamer, I. M., Gassler, J., Imakaev, M., Brandão, H. B., Ulianov, S. V., Abdennur, N., Razin, S. V., Mirny, L. A., & Tachibana-Konwalski, K. (2017) · Nature
Genomics and Chromatin DynamicsChromosomal and Genetic Variations
Cited by 753
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Comprehensive comparative analysis of strand-specific RNA sequencing methods
Levin, J. Z., Yassour, M., Adiconis, X., Nusbaum, C., Thompson, D. A., Friedman, N., Gnirke, A., & Regev, A. (2010) · Nature Methods
Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics
Cited by 753
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NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo
Jia, G., Han, Y., An, Y., Ding, Y., He, C., Wang, X., & Tang, Q. (2018) · Biomaterials
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 753
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Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis
Wu, H., Kirita, Y., Donnelly, E. L., & Humphreys, B. D. (2019) · Journal of the American Society of Nephrology
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 752
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Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies
Delbridge, A. R. D., Grabow, S., Strasser, A., & Vaux, D. L. (2016) · Nature Reviews Cancer
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 752
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Functional organization of the transcriptome in human brain
Oldham, M. C., Konopka, G., Iwamoto, K., Langfelder, P., Kato, T., Horvath, S., & Geschwind, D. H. (2008) · Nature Neuroscience
Gene expression and cancer classificationSingle-cell and spatial transcriptomics
Cited by 752
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Targeted disruption of the chop gene delays endoplasmic reticulum stress-mediated diabetes
Oyadomari, S., Koizumi, A., Takeda, K., Gotoh, T., Akira, S., Araki, E., & Mori, M. (2002) · Journal of Clinical Investigation
Endoplasmic Reticulum Stress and DiseasePancreatic function and diabetes
Cited by 752
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Nrf2, the Master Regulator of Anti-Oxidative Responses
Vomund, S., Schäfer, A., Parnham, M., Brüne, B., & Von Knethen, A. (2017) · International Journal of Molecular Sciences
Genomics, phytochemicals, and oxidative stressNF-κB Signaling Pathways
Cited by 752
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Identification of the Switch in Early-to-Late Endosome Transition
Poteryaev, D., Datta, S., Ackema, K., Zerial, M., & Spang, A. (2010) · Cell
Cellular transport and secretionAutophagy in Disease and Therapy
Cited by 752
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Utrophin–dystrophin-deficient mice as a model for Duchenne muscular dystrophy
Deconinck, A. E., Rafael, J. A., Skinner, J. A., Brown, S. C., Potter, A. C., Metzinger, L., Watt, D. J., Dickson, J. G., Tinsley, J. M., & Davies, K. E. (1997) · Cell
Muscle Physiology and DisordersNeurogenetic and Muscular Disorders Research
Cited by 752
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Influence of the Gut Microbiome, Diet, and Environment on Risk of Colorectal Cancer
Song, M., Chan, A. T., & Sun, J. (2020) · Gastroenterology
Gut microbiota and healthNutritional Studies and Diet
Cited by 752
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Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
Hon, W.-C., Wilson, M. I., Harlos, K., Claridge, T. D. W., Schofield, C. J., Pugh, C. W., Maxwell, P. H., Ratcliffe, P. J., Stuart, D. I., & Jones, E. Y. (2002) · Nature
Cancer, Hypoxia, and MetabolismUbiquitin and proteasome pathways
Cited by 751
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Oxidative stress and apoptosis: Impact on cancer therapy
Ozben, T. (2007) · Journal of Pharmaceutical Sciences
Cell death mechanisms and regulationRedox biology and oxidative stress
Cited by 751
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Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress
Rodgers, A. B., Morgan, C. P., Leu, N. A., & Bale, T. L. (2015) · Proceedings of the National Academy of Sciences
Epigenetics and DNA MethylationBirth, Development, and Health
Cited by 751
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Calcium and neurodegeneration
Mattson, M. P. (2007) · Aging Cell
Mitochondrial Function and PathologyIon channel regulation and function
Cited by 751
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